Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating Glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Hepatology

Volumn 56, Issue 1, 2012, Pages 186-197

  Wang, Bo ^a   Hsu, Shu Hao ^a   Frankel, Wendy ^a   Ghoshal, Kalpana ^a,b   Jacob, Samson T ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b 646 Tzagournis Medical Research Facility   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE 6 PHOSPHATASE; INTERLEUKIN 6; MESSENGER RNA; MICRORNA; MICRORNA 23A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GRADING; CANCER SIZE; CANCER STAGING; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; ANALYSIS OF VARIANCE; ANIMALS; CARCINOMA, HEPATOCELLULAR; DIET; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCONEOGENESIS; GLUCOSE-6-PHOSPHATASE; HUMANS; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; MICRORNAS; MIDDLE AGED; PPAR GAMMA; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STATISTICS, NONPARAMETRIC; TRANSCRIPTION FACTORS;

EID: 84863526545     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25632     Document Type: Article

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