Transdifferentiation of MALME-3m and MCF-7 cells toward adipocyte-like cells is dependent on clathrin-mediated endocytosis

SpringerPlus

Volumn 1, Issue 1, 2012, Pages 1-12

  Carcel Trullols, Jaime ^a   Aguilar Gallardo, Cristóbal ^a   Garcia Alcalde, Fernando ^a   Pardo Cea, Miguel Angel ^a   Dopazo, Joaquin ^a   Conesa, Ana ^a   Simón, Carlos ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

Adipogenic gene markers; Cell transdifferentiation; Clathrin; Clathrin mediated Endocytosis; Loss of pigmentation; Perilipin 2; PPARG; Unsaturated fatty acids

Indexed keywords

EID: 84873517744     PISSN: None     EISSN: 21931801     Source Type: Journal    
DOI: 10.1186/2193-1801-1-44     Document Type: Article

References (51)

1. Andersson ER (2012) The role of endocytosis in activating and regulating signal transduction. Cell Mol Life Sci 69(11):1755-1771
2. Ben Gedalya T, Loeb V, Israeli E, Altschuler Y, Selkoe DJ, Sharon R (2009) Alphasynuclein and polyunsaturated fatty acids promote CLTC-mediated endocytosis and synaptic vesicle recycling. Traffic 10(2):218-234
3. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of The Royal Statistical Society Series B 57:289-300
4. Brasaemle DL, Barber T, Wolins NE, Serrero G, Blanchette-Mackie EJ, Londos C (1997) Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 38(11):2249-2263
5. Chernomordik LV, Leikina E, Frolov V, Bronk P, Zimmerberg J (1997) An early stage of membrane fusion mediated by the low pH conformation of influenza hemagglutinin depends upon membrane lipids. J Cell Biol 136(1):81-93
6. Chernomordik LV, Leikina E, Kozlov MM, Frolov VA, Zimmerberg J (1999) Structural intermediates in influenza haemagglutinin-mediated fusion. Mol Membr Biol 16(1):33-42
7. Conner SD, Schmid SL (2003) Regulated portals of entry into the cell. Nature 422(6927):37-44
8. Darios F, Davletov B (2006) Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3. Nature 440(7085):813-817
9. Davis BD, Dubos RJ (1947) The Binding of Fatty Acids by Serum Albumin, a Protective Growth Factor in Bacteriological Media. J Exp Med 86(3):215-228
10. De Maziere AM, Muehlethaler K, van Donselaar E, Salvi S, Davoust J, Cerottini JC et al (2002) The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins. Traffic 3(9):678-693
11. El-Jack AK, Kandror KV, Pilch PF (1999) The Formation of an Insulin-responsive Vesicular Cargo Compartment Is an Early Event in 3T3-L1 Adipocyte Differentiation. Mol Biol Cell 10(5):1581-1594
12. Finn RD, Mistry J, Tate J, Coggill P, Heger A, Pollington JE et al (2010) The Pfam protein families database. Nucleic Acids Res 38:211-222
13. Garcia-Gonzalo FR, Izpisua Belmonte JC (2008) Albumin associated lipids regulate human embryonic stem cell selfrenewal. PLoS One 3(1):e1384
14. Gillingham AK, Koumanov F, Pryor PR, Reaves BJ, Holman GD (1999) Association of AP1 adaptor complexes with GLUT4 vesicles. J Cell Sci 112(24):4793-4800
15. Graf T, Enver T (2009) Forcing cells to change lineages. Nature 462(7273):587-594
16. Greenspan P, Mayer EP, Fowler SD (1985) Nile red: a selective fluorescent stain for intracellular lipid droplets. J Cell Biol 100(3):965-973
17. Hanover JA, Willingham MC, Pastan I (1984) Kinetics of transit of transferrin and epidermal growth factor through clathrin-coated membranes. Cell 39(2):283-293
18. Heid HW, Moll R, Schwetlick I, Rackwitz HR, Keenan TW (1998) Perilipin 2 is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res 294(2):309-321
19. Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira WD, Hearing VJ (2005) MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes. J Biol Chem 280(14):14006-14016
20. Huang S, Lifshitz LM, Jones C, Bellve KD, Standley C, Fonseca S et al (2007) Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes. Mol Cell Biol 27(9):3456-3469
21. Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG et al (2010) Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142(3):375-386
22. Inoue Y, Tanaka N, Tanaka Y, Inoue S, Morita K, Zhuang M et al (2007) CLTCdependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted. J Virol 81 (16):8722-8729
23. Kakizuka A, Miller WH Jr, Umesono K et al (1991) Chromosomal translocationt(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 66(4):663-74
24. Kallee E (1996) Bennhold's analbuminemia: a follow-up study of the first two cases (1953-1992). J Lab Clin Med 127(5):470-480
25. Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli WJ (1999) Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103(11):1489-1498
26. Khan AA, Husain A, Jabeen M, Mustafa J, Owais M (2012) Synthesis and Characterization of Novel n-9 Fatty Acid Conjugates Possessing Antineoplastic Properties. Lipids. doi:10.1007/s1174501237079
27. Kim HJ, Jung TW, Kang ES, Kim DJ, Ahn CW, Lee KW et al (2007) Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model. Metabolism 56(5):676-685
28. Kutt H, Tsaltas TT (1959) Staining properties of oil red O and a method of partial purification of the commercial product. Clin Chem 5(2):149-160
29. Lafond J, Simoneau L, Savard R, Gagnon MC (1994) Linoleic acid transport by human placental syncytiotrophoblast membranes. Eur J Biochem 226(2):707-713
30. Levin JZ, Yassour M, Adiconis X, Nusbaum C, Thompson DA et al (2010) Comprehensive comparative analysis of strand-specific RNA sequencing methods. Nat Methods 7(9):709-715
31. Long G, Pan X, Kormelink R, Vlak JM (2006) Functional entry of baculovirus into insect and mammalian cells is dependent on CLTC-mediated endocytosis. J Virol 80(17):8830-8833
32. Maxfield FR, McGraw TE (2004) Endocytic recycling. Nat Rev Mol Cell Biol 5 (2):121-132
33. Mead JR, Irvine SA, Ramji DP (2002) Lipoprotein lipase: structure, function, regulation, and role in disease. Mol Med (Berl) 80(12):753-769
34. Mersmann HJ, Goodman JR, Brown LJ (1975) Development of swine adipose tissue: morphology and chemical composition. J Lipid Res 16(4):269-279
35. Parkhomchuk D, Borodina T, Amstislavskiy V, Banaru M, Hallen L, Krobitsch S et al (2009) Transcriptome analysis by strand-specific sequencing of complementary DNA. Nucleic Acids Res 37(18):e123
36. Pearse BM, Smith CJ, Owen DJ (2000) CLTC coat construction in endocytosis. Curr Opin Struct Biol 10(2):220-228
37. Raposo G, Marks MS (2007) Melanosomes - dark organelles enlighten endosomal membrane transport. Nat Rev Mol Cell Biol 8(10):786-797
38. Rauch C, Brunet AC, Deleule J, Farge E (2002) C2C12 myoblast/osteoblast transdifferentiation steps enhanced by epigenetic inhibition of BMP2 endocytosis. Am J Physiol Cell Physiol 283(1):235-243
39. Ruiz-Vela A, Aguilar-Gallardo C, Simon C (2009) Building a framework for embryonic microenvironments and cancer stem cells. Stem Cell Reviews and Reports 5(4):319-27
40. Ruiz-Vela A, Aguilar-Gallardo C, Martínez-Arroyo AM, Soriano-Navarro M, Ruiz V et al (2011) Specific Unsaturated Fatty Acids Enforce the Transdifferentiation of Human Cancer Cells toward Adipocyte-like Cells. Stem Cell Reviews and Reports 7(4):898-909
41. Schopfer FJ, Lin Y, Baker PR, Cui T, Garcia-Barrio M, Zhang J et al (2005) Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand. Proc Natl Acad Sci U S A 102(7):2340-2345
42. Stephens JM, Lee J, Pilch PF (1997) Tumor necrosis factor α-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptormediated signal transduction. J Biol Chem 272(2):971-976
43. Sullivan AL, Grasso JA, Weintraub LR (1976) Micropinocytosis of transferrin by developing red cells: an electron-microscopic study utilizing ferritinconjugated transferrin and ferritin-conjugated antibodies to transferrin. Blood 47(1):133-143
44. Takeuchi JK, Bruneau BG (2009) Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature 459(7247):708-711
45. Tarazona S, Garcia-Alcalde F, Ferrer A, Dopazo J, Conesa A (2011) Differential expression in RNA-seq: a matter of depth. Genome Res 21(12):2213-2223
46. Thomas ME, Morrison AR, Schreiner GF (1995) Metabolic effects of fatty acidbearing albumin on a proximal tubule cell line. Am J Physiol 268(6):1177-1184
47. Todaro GJ, Green H (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 17:299-313
48. Trapnell C, Pachter L, Salzberg SL (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25(9):1105-11
49. Young MD, Wakefield MJ, Smyth GK, Oshlack A (2010) Gene ontology analysis for RNA-seq: accounting for selection bias. Genome Biol 11(2):R14
50. Yu J, Li Y, Li M, Qu Z, Ruan Q (2010) Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cells in vitro. Int J Exp Pathol 91(1):24-33
51. Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA (2008) In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455 (7213):627-632