Antihepatofibrotic Effects of Aqueous Extract of Prunella vulgaris on Carbon Tetrachloride-Induced Hepatic Fibrosis in Rats

Planta Medica

Volumn 82, Issue 1-2, 2015, Pages 97-105

  Hu, Yi Xiang ^a   Yu, Chen Huan ^a   Wu, Fang ^b   Yu, Wen Ying ^a   Zhong, Yu Sen ^a   Ying, Hua Zhong ^a   Yu, Bing ^b  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

antihepatofibrotic effects; flavonoids; hepatic stellate cells; Labiatae; microRNA; Prunella vulgaris; triterpenoids

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; COLLAGENASE 3; GELATINASE A; HYALURONIC ACID; INTERLEUKIN 4; INTERLEUKIN 8; LIVER PROTECTIVE AGENT; MESSENGER RNA; MICRORNA 199A 5P; MICRORNA 34A; PLATELET DERIVED GROWTH FACTOR; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; PRUNELLA VULGARIS EXTRACT; SCLEROPROTEIN; SMAD2 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; PLANT EXTRACT; PROTECTIVE AGENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CELL ACTIVATION; COLLAGEN DEGRADATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; LOW DRUG DOSE; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; PRUNELLA; PRUNELLA VULGARIS; RANDOMIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; LIVER CIRRHOSIS;

ANIMALS; CARBON TETRACHLORIDE; LIVER CIRRHOSIS; MALE; PLANT EXTRACTS; PROTECTIVE AGENTS; PRUNELLA; RATS;

EID: 84954104076     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0035-1558112     Document Type: Article

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