Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-κB-dependent MMP-9 expression

Food and Chemical Toxicology

Volumn 48, Issue 2, 2010, Pages 564-571

  Choi, Jae Ho ^a,b   Han, Eun Hee ^a,b   Hwang, Yong Pil ^a,b   Choi, Jun Min ^c   Choi, Chul Yung ^c   Chung, Young Chul ^c   Seo, Jong Kwon ^c   Jeong, Hye Gwang ^a  

^a Chungnam National University   (South Korea)

^b Chosun University   (South Korea)

^c Korea International University   (South Korea)

Author keywords

Anti metastatic; ERK1 2; MMP 9; NF B; Prunella vulgaris

Indexed keywords

GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL 13 ACETATE 12 MYRISTATE; PRUNELLA VULGARIS EXTRACT; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; C57BL 6 MOUSE; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG ISOLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MALE; MELANOMA; MELANOMA B16; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR GROWTH;

ADMINISTRATION, ORAL; ANIMALS; CELL MOVEMENT; CELL NUCLEUS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 9; MELANOMA; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NF-KAPPA B; PHOSPHORYLATION; PLANT EXTRACTS; PRUNELLA; TETRADECANOYLPHORBOL ACETATE; TRANSLOCATION, GENETIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; PRUNELLA VULGARIS;

EID: 74649086132     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.11.033     Document Type: Article

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