Effect and mechanism of methyl helicterate isolated from Helicteres angustifolia (Sterculiaceae) on hepatic fibrosis induced by carbon tetrachloride in rats

Journal of Ethnopharmacology

Volumn 143, Issue 3, 2012, Pages 889-895

  Huang, Quanfang ^a   Li, Yongwen ^c   Zhang, Shijun ^b   Huang, Renbin ^b   Zheng, Li ^b   Wei, Ling ^b   He, Min ^b   Liao, Ming ^b   Li, Li ^c   Zhuo, Lang ^b,d   Lin, Xing ^b  

^a GUANGXI UNIVERSITY OF CHINESE MEDICINE   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

^c GUILIN MEDICAL UNIVERSITY   (China)

^d INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

Carbon tetrachloride; Hepatic fibrosis; Methyl helicterate; Oxidative stress; Transforming growth factor 1 (TGF 1)

Indexed keywords

3BETA ACETOXY 27 BENZOYLOXYUP 20(29) EN 28 OIC ACID METHYLESTER; ALANINE AMINOTRANSFERASE; ALBUMIN; ANTIFIBROTIC AGENT; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; COLCHICINE; COLLAGEN TYPE 3; GLUTATHIONE PEROXIDASE; HYALURONIC ACID; HYDROXYPROLINE; LAMININ; MALONALDEHYDE; MESSENGER RNA; PROCOLLAGEN; SMAD3 PROTEIN; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TRITERPENOID; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; HELICTERES ANGUSTIFOLIA; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER FUNCTION; LOW DRUG DOSE; MALE; MALVACEAE; MEDICINAL PLANT; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE; COLLAGEN TYPE III; GLUTATHIONE PEROXIDASE; HYALURONIC ACID; HYDROXYPROLINE; LAMININ; LIPID PEROXIDATION; LIVER CIRRHOSIS; MALE; PHYTOTHERAPY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SMAD3 PROTEIN; STERCULIACEAE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TRITERPENES;

ARACHIS HYPOGAEA; HELICTERES ANGUSTIFOLIA; MALVACEAE; RATTUS;

EID: 84866742039     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.08.018     Document Type: Article

References (33)

1. G.S. Achliya, S.G. Wadodkar, and A.K. Dorle Evaluation of hepatoprotective effect of Amalkadi Ghrita against carbon tetrachloride induced hepatic damage in rats Journal of Ethnopharmacology 90 2004 229 232
2. R. Bataller, and D.A. Brenner Hepatic stellate cells as a target for the treatment of liver fibrosis Seminars in Liver Disease 21 2001 437 451
3. R. Bataller, and D.A. Brenner Liver fibrosis Journal of Clinical Investigation 115 2005 209 218
4. P.A. Bonis, S.L. Friedman, and M.M. Kaplan Is liver fibrosis reversible? New England Journal of Medicine 344 2001 452 454
5. M. Cabre, J. Camps, J.L. Paternain, N. Ferre, and J. Joven Time-course of changes in hepatic lipid peroxidation and glutathione metabolism in rats with carbon tetrachloride-induced cirrhosis Clinical and Experimental Pharmacology and Physiology 27 2000 694 699
6. G. Drewa, E. Krzyzynska-Malinowska, A. Wozniak, F. Protas-Drozd, C. Mila-Kierzenkowska, M. Rozwodowska, B. Kowaliszyn, and R. Czajkowski Activity of superoxide dismutase and catalase and the level of lipid peroxidation products reactive with TBA in patients with psoriasis Medical Science Monitor 8 2002 BR338 BR343
7. W.D. Du, Y. Zhang, W.R. Zhai, and X.M. Zhou Dynamic changes of type I, III and IV collagen synthesis and distribution of collagen-producing cells in carbon tetrachloride - induced rat liver fibrosis World Journal of Gastroenterology 5 1999 397 403
8. A.M. Gressner, R. Weiskirchen, K. Breitkopf, and S. Dooley Roles of TGF beta in hepatic fibrosis Frontiers in Bioscience 7 2002 d793 d807
9. A.M. Gressner, and R. Weiskirchen Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets Journal of Cellular and Molecular Medicine 10 2006 76 99
10. 4-induced cirrhosis: protective role of adenosine administration Hepatology 26 1997 1100 1110
11. C.S. Hill Identification of a Smad phosphatase ACS Chemical Biology 1 2006 346 348
12. S. Itoh, and P. ten Dijke Negative regulation of TGF-beta receptor/Smad signal transduction Current Opinion in Cell Biology 19 2007 176 184
13. I.S. Jamall, V.N. Finelli, and S.S. Que Hee A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues Analytical Biochemistry 112 1981 70 75
14. X. Lin, Z.Q. Feng, E.Y. Lu, S.Q. Liang, J.S. Huang, X.P. Li, and Q.H. Luo Influence of the water extract from Helicteres angustifolia on protein expression of α-SMA, TIMP-1 in rats with hepatic fibrosis Shandong Medical Journal 7 2010 46 47
15. X. Lin, S.J. Zhang, M. Liao, and R.B. Huang Effects of the extract of Helicteres angustifolia on Col I mRNA and Col I protein expressions in hepatic tissue of rats with hepatic fibrosis China Pharmacy 43 2010 4041 4043
16. X. Lin, S.J. Zhang, M. Liao, and R.B. Huang Influence of the water extract from Helicteres angustifolia on serum makers in rats with hepatic fibrosis Lishzhen Medicine and Materia Medica Research 21 2010 3085 3086
17. X. Lin, S.J. Zhang, M. Liao, and R.B. Huang Influence of water extract from Helicteres angustifolia on lipid peroxidation induced by carbon tetrachlorile in mice Chinese Journal of Experimental Traditional Medical Formulae 16 2010 147 149
18. H. Makita, T. Tanaka, and H. Fujitska Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone and quercetin Cancer Research 56 1996 4904 4909
19. C.J. Parsons, M. Takashima, and R.A. Rippe Molecular mechanisms of hepatic fibrogenesis Journal of Gastroenterology and Hepatology 22 2007 S79 S84
20. G. Poli Pathogenesis of liver fibrosis: role of oxidative stress Molecular Aspects of Medicine 21 2000 49 98
21. L. Reddy, B. Odhav, and K.D. Bhoola Natural products for cancer prevention: a global perspective Pharmacology and Therapeutics 99 2003 1 13
22. C.E. Runyan, A.C. Poncelet, and H.W. Schnaper TGF-beta receptor binding proteins: complex interactions Cellular Signaling 18 2006 2077 2088
23. R. Safadi, and S.L. Friedman Hepatic fibrosis-role of hepatic stellate cell activation Medscape General Medicine 4 2002 27
24. R.F. Schwabe, and W. Stremmel The natural course of hepatitis B and hepatitis C virus infection Schweizerische Rundschau für Medizin PRAXIS 87 1998 1403 1407
25. F.W. Shek, and R.C. Benyon How can transforming growth factor beta be targeted usefully to combat liver fibrosis? European Journal of Gastroenterology and Hepatology 16 2004 123 126
26. I. Shimizu, Y.R. Ma, Y. Mizobuchi, F. Liu, T. Miura, Y. Nakai, M. Yasuda, M. Shiba, T. Horie, S. Amagaya, N. Kawada, H. Hori, and S. Ito Effects of Sho-saiko-to, a Japanese herbal medicine, on hepatic fibrosis in rats Hepatology 29 1999 149 160
27. G. Tarantino, P. Conca, A. Riccio, M. Tarantino, M.N. Di Minno, D. Chianese, F. Pasanisi, F. Contaldo, F. Scopacasa, and D. Capone Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign? Journal of Translational Medicine 6 2008 72
28. F. Verrecchia, and A. Mauviel Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation Journal of Investigative Dermatology 118 2002 211 215
29. S. Wasser, and C.E. Tan Experimental models of hepatic fibrosis in the rat Annals of the Academy of Medicine 28 1999 109 111
30. Y.R. Wei, G.C. Wang, X.Q. Zhang, Y. Wang, and W.C. Ye Studies on chemical constituents in roots of Helicteres angustifolia China Journal of Chinese Materia Medica 36 2011 1193 1197
31. S.J. Wicks, T. Grocott, K. Haros, M. Maillard, P. ten Dijke, and A. Chantry Reversible ubiquitination regulates the Smad/TGF-beta signalling pathway Biochemical Society Transactions 34 2006 761 763
32. L. Xu Regulation of Smad activities Biochimica et Biophysica Acta 1759 2006 503 513
33. Y.H. Zou, Y. Yang, J. Li, Q. Wu, W.P. Li, J.T. Lu, and Michael S. Roberts Potential therapeutic effects of a traditional Chinese formulation, BJ-JN, on liver fibrosis induced by carbon tetrachloride in rats Journal of Ethnopharmacology 120 2008 452 457