Lipid metabolites of the phospholipase A2 pathway and inflammatory cytokines are associated with brain volume in paediatric cerebral malaria

Malaria Journal

Volumn 14, Issue 1, 2015, Pages

  Pappa, Vasiliki ^a   Seydel, Karl ^b,c   Gupta, Sanchit ^a   Feintuch, Catherine M ^a   Potchen, Michael J ^d,e   Kampondeni, Samuel ^b   Goldman Yassen, Adam ^a   Veenstra, Mike ^a   Lopez, Lillie ^a   Kim, Ryung S ^a   Berman, Joan W ^a   Taylor, Terrie ^b,c   Daily, Johanna P ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MALAWI   (Malawi)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d UNIVERSITY OF ROCHESTER   (United States)

^e Lusaka Apex Medical University   (Zambia)

Author keywords

Brain swelling; Cerebral malaria; Cytokines; Inflammation; Phospholipase A2; Plasma small molecules; Plasmodium falciparum

Indexed keywords

ARACHIDONIC ACID; CYTOKINE; INTERLEUKIN 8; LIPID; LYSOPHOSPHOLIPID; PHOSPHOLIPASE A2; TIGHT JUNCTION PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN DISEASE; BRAIN MALARIA; BRAIN SIZE; BRAIN SWELLING; CHILD; CYTOKINE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE COURSE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INDUCTION; FEMALE; HUMAN; HUMAN CELL; INFANT; MAJOR CLINICAL STUDY; MALAWIAN; MALE; MEMBRANE PERMEABILITY; METABOLITE; METABOLOMICS; PATHOPHYSIOLOGY; PHOSPHOLIPASE A2 BLOOD LEVEL; PRESCHOOL CHILD; PROTEIN BLOOD LEVEL; SCHOOL CHILD; TUMOR NECROSIS FACTOR ALPHA BLOOD LEVEL; ANIMAL; BLOOD; BRAIN; CEREBRAL MALARIA; COHORT ANALYSIS; LIPID METABOLISM; MALAWI; METABOLISM; PATHOLOGY;

ANIMALS; BRAIN; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; CYTOKINES; HUMANS; INFANT; LIPID METABOLISM; LIPIDS; MALARIA, CEREBRAL; MALAWI; PHOSPHOLIPASES A2;

EID: 84954059968     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-015-1036-1     Document Type: Article

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