Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors

Journal of Neurochemistry

Volumn 135, Issue 5, 2015, Pages 867-879

  Dalvi, Siddhartha ^a   Nguyen, Hieu H ^a   On, Ngoc ^a   Mitchell, Ryan W ^a   Aukema, Harold M ^a   Miller, Donald W ^a   Hatch, Grant M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

arachidonic acid; blood brain barrier; endothelial cells; fatty acid

Indexed keywords

ARACHIDONIC ACID; CARBON 14; CAY 1058; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DEXTRAN; FLUORESCEIN; INDOMETACIN; L 798 106; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CD36 ANTIGEN; ISOTOPE; OLEIC ACID; ORGANIC ANION TRANSPORTER; PTGS1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; SLCO2A1 PROTEIN, HUMAN;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME INHIBITION; FATTY ACID TRANSPORT; GENE SILENCING; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RADIOACTIVITY; TRANSPORT MEDIUM; UPREGULATION; ANATOMY AND HISTOLOGY; BRAIN; CAPILLARY PERMEABILITY; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROVASCULATURE; PHYSIOLOGY;

ANTIGENS, CD36; ARACHIDONIC ACID; BRAIN; CAPILLARY PERMEABILITY; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DEXTRANS; DINOPROSTONE; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; ISOTOPES; MICROVESSELS; OLEIC ACID; ORGANIC ANION TRANSPORTERS; PROSTAGLANDIN ANTAGONISTS; RECEPTORS, PROSTAGLANDIN E, EP3 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; RNA, SMALL INTERFERING;

EID: 84955170591     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13117     Document Type: Article

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