Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells

Journal of Immunology

Volumn 165, Issue 5, 2000, Pages 2773-2782

  Fonteh, A N ^a   Atsumi, G I ^a   LaPorte, T ^a   Chilton, F H ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ARACHIDONIC ACID; COMPLEMENTARY DNA; FATTY ACID; HERBIMYCIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHOLIPASE A2; CELL SURFACE RECEPTOR; ENZYME INHIBITOR; FLAVONOID; GROUP II SECRETORY PHOSPHOLIPASE A2; ISOENZYME; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE A; PHOSPHOLIPASE A2 IV; PHOSPHOLIPASE A2 RECEPTOR;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; MAST CELL; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; BIOSYNTHESIS; CBA MOUSE; CELL CULTURE; CYTOSOL; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; ARACHIDONIC ACID; BONE MARROW CELLS; CELLS, CULTURED; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; ISOENZYMES; LIGANDS; MAST CELLS; MICE; MICE, INBRED CBA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 0034257927     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.5.2773     Document Type: Article

References (65)

1. 2
2. 2 superfamily of signal transduction enzymes
3. 2 gene family in mammals
4. 2
5. 2
6. 2s
7. 2
8. Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2
9. 2 gene multiple enzymes with distinct properties from a single gene
10. 2
11. 2 is the principal bactericide for staphylococci and other Gram-positive bacteria in human tears
12. 2: Structural and functional changes
13. Antigen-induced generation of lyso-phospholipids in human airways
14. 2 levels in acute chest syndrome of sickle cell disease
15. 2 protein interaction
16. 2 and C-reactive protein in the removal of injured cells
17. 2 activities are increased in human adult respiratory distress syndrome
18. 2 activities are decreased during early but increased during late phases of sepsis in rat heart
19. 2 inhibitor in acute pancreatitis
20. 2 in sepsis: Studies in nonhuman primates after interleukin-1α administration and during lethal bacteremia
21. 2 in rheumatoid arthritis
22. 2 in synovial fluid and serum in acute arthritis
23. 2 and arachidonate increase in bronchoalveolar lavage fluid after inhaled antigen challenge in asthmatics
24. 2 confirms the systemic inflammatory nature of adjuvant arthritis
25. 2 in human male reproductive organs and genital tumors
26. 2 in human breast cancer tissues is closely associated with their malignant potency
27. 2 stimulates the growth of human pancreatic cancer cell line
28. 2 messenger RNA and protein in colorectal adenomas from familial adenomatous polyposis patients
29. 2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
30. 2A) expression status in colorectal carcinoma derived cell lines and in normal colonic mucosa
31. 2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cells
32. 2 by P388D1 cells
33. 2 generation in mouse bone marrow-derived mast cells
34. 2
35. 2 that mediates prostaglandin production in mast cells
36. 2 induced prominent release of arachidonic acid from human myeloid leukemia cells
37. 2-induced inflammation
38. 2 from Vipera russelli snake venom by guanidination of lysine residues
39. 2 is separable from its enzymatic activity
40. 2
41. 2 receptor
42. 2
43. 2 are natural ligands of the mouse 180-kDa M-type receptor
44. 2 involved in N-type receptor binding and neurotoxicity
45. 2 to its specific receptor
46. 2 in the human astrocytoma cell line 1321N1
47. 2 in a human pancreatic cancer cell line
48. 2 via its high affinity receptor stimulates extracellular matrix invasion by normal and cancer cells
49. 2+ mobilization in the human astrocytoma cell line 1321N1 by a mechanism independent of its catalytic activity
50. A rapid method of total lipid extraction and purification
51. Mobilization of different arachidonate pools and their roles in the generation of leukotrienes and free arachidonic acid during immunologic activation of mast cells
52. 2 by p42 microtubule-associated protein 2 kinase and protein kinase C
53. Antigen activation of mitogen-activated protein kinase in mast cells through protein kinase C-dependent and independent pathways
54. Control of the ERK MAP kinase cascade by Ras and Raf
55. JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone
56. 2 enzymes have different intracellular locations in mouse bone marrow-derived mast cells
57. 2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase
58. 2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen
59. 2 in rat renal mesangial cells
60. 2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells
61. 2 in vascular smooth-muscle cells
62. 2 and the release of arachidonic acid in human neutrophils
63. 2
64. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-α and release of arachidonic acid in mast cells: Indications of communication between p38 and p42 MAP kinases
65. 2 by oncogenic Ras in human non-small cell lung cancer