메뉴 건너뛰기




Volumn 2016, Issue , 2016, Pages

Endurance and resistance training affect high fat diet-induced increase of ceramides, inflammasome expression, and systemic inflammation in mice

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CERAMIDE; CHEMOKINE; CRYOPYRIN; FATTY ACID; INFLAMMASOME; INTERLEUKIN 18; MACROPHAGE INFLAMMATORY PROTEIN 1GAMMA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CARRIER PROTEIN; CERS4 PROTEIN, MOUSE; CYTOKINE; GLUCOSE BLOOD LEVEL; NLRP3 PROTEIN, MOUSE; SERINE PALMITOYLTRANSFERASE; SPHINGOSINE ACYLTRANSFERASE; SPTLC2 PROTEIN, MOUSE;

EID: 84953889295     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/4536470     Document Type: Article
Times cited : (48)

References (50)
  • 2
    • 84865297442 scopus 로고    scopus 로고
    • The inflammation highway: Metabolism accelerates inflammatory traffic in obesity
    • A. R. Johnson, J. Justin Milner, and L. Makowski, "The inflammation highway: metabolism accelerates inflammatory traffic in obesity," Immunological Reviews, vol. 249, no. 1, pp. 218-238, 2012.
    • (2012) Immunological Reviews , vol.249 , Issue.1 , pp. 218-238
    • Johnson, A.R.1    Justin Milner, J.2    Makowski, L.3
  • 3
    • 4644229516 scopus 로고    scopus 로고
    • Exercise-induced reduction in obesity and insulin resistance in women: A randomized controlled trial
    • R. Ross, I. Janssen, J. Dawson et al., "Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial," Obesity Research, vol. 12, no. 5, pp. 789-798, 2004.
    • (2004) Obesity Research , vol.12 , Issue.5 , pp. 789-798
    • Ross, R.1    Janssen, I.2    Dawson, J.3
  • 4
    • 84922945073 scopus 로고    scopus 로고
    • Involvement of de novo ceramide synthesis in pro-inflammatory adipokine secretion and adipocyte-macrophage interaction
    • Y. Hamada, H. Nagasaki, A. Fujiya et al., "Involvement of de novo ceramide synthesis in pro-inflammatory adipokine secretion and adipocyte-macrophage interaction," The Journal of Nutritional Biochemistry, vol. 25, no. 12, pp. 1309-1316, 2014.
    • (2014) The Journal of Nutritional Biochemistry , vol.25 , Issue.12 , pp. 1309-1316
    • Hamada, Y.1    Nagasaki, H.2    Fujiya, A.3
  • 5
    • 33847332202 scopus 로고    scopus 로고
    • Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
    • W. L. Holland, J. T. Brozinick, L.-P. Wang et al., "Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance," CellMetabolism, vol. 5, no. 3, pp. 167-179, 2007.
    • (2007) CellMetabolism , vol.5 , Issue.3 , pp. 167-179
    • Holland, W.L.1    Brozinick, J.T.2    Wang, L.-P.3
  • 7
    • 84858749132 scopus 로고    scopus 로고
    • Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials
    • G. A. Kelley, K. S. Kelley, S. Roberts, and W. Haskell, "Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials," Clinical Nutrition, vol. 31, no. 2, pp. 156-167, 2012.
    • (2012) Clinical Nutrition , vol.31 , Issue.2 , pp. 156-167
    • Kelley, G.A.1    Kelley, K.S.2    Roberts, S.3    Haskell, W.4
  • 8
    • 84888212859 scopus 로고    scopus 로고
    • Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet
    • article 3267
    • N. Goto-Inoue, K. Yamada, A. Inagaki et al., "Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet," Scientific Reports, vol. 3, article 3267, 2013.
    • (2013) Scientific Reports , vol.3
    • Goto-Inoue, N.1    Yamada, K.2    Inagaki, A.3
  • 9
    • 79952389476 scopus 로고    scopus 로고
    • Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats
    • A. G. Oliveira, B. M. Carvalho, N. Tobar et al., "Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats," Diabetes, vol. 60, no. 3, pp. 784-796, 2011.
    • (2011) Diabetes , vol.60 , Issue.3 , pp. 784-796
    • Oliveira, A.G.1    Carvalho, B.M.2    Tobar, N.3
  • 10
    • 77957940963 scopus 로고    scopus 로고
    • Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching fromM1 toM2 macrophages in high-fatdiet-induced obese mice
    • N. Kawanishi, H. Yano, Y. Yokogawa, and K. Suzuki, "Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching fromM1 toM2 macrophages in high-fatdiet-induced obese mice," Exercise Immunology Review, vol. 16, pp. 105-118, 2010.
    • (2010) Exercise Immunology Review , vol.16 , pp. 105-118
    • Kawanishi, N.1    Yano, H.2    Yokogawa, Y.3    Suzuki, K.4
  • 11
    • 39749099343 scopus 로고    scopus 로고
    • Endurance training and obesity: Effect on substrate metabolism and insulin sensitivity
    • M. C. Venables and A. E. Jeukendrup, "Endurance training and obesity: effect on substrate metabolism and insulin sensitivity," Medicine and Science in Sports and Exercise, vol. 40, no. 3, pp. 495-502, 2008.
    • (2008) Medicine and Science in Sports and Exercise , vol.40 , Issue.3 , pp. 495-502
    • Venables, M.C.1    Jeukendrup, A.E.2
  • 12
    • 79955477135 scopus 로고    scopus 로고
    • Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients
    • S. M. Abd El-Kader, "Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients," Journal of Advanced Research, vol. 2, no. 2, pp. 179-183, 2011.
    • (2011) Journal of Advanced Research , vol.2 , Issue.2 , pp. 179-183
    • Abd El-Kader, S.M.1
  • 13
    • 0042288034 scopus 로고    scopus 로고
    • A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes
    • C. Castaneda, J. E. Layne, L. Munoz-Orians et al., "A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes," Diabetes Care, vol. 25, no. 12, pp. 2335-2341, 2002.
    • (2002) Diabetes Care , vol.25 , Issue.12 , pp. 2335-2341
    • Castaneda, C.1    Layne, J.E.2    Munoz-Orians, L.3
  • 14
    • 0031448970 scopus 로고    scopus 로고
    • Resistance training improves the metabolic profile in individuals with type 2 diabetes
    • A. Honkola, T. Forsen, and J. Eriksson, "Resistance training improves the metabolic profile in individuals with type 2 diabetes," Acta Diabetologica, vol. 34, no. 4, pp. 245-248, 1997.
    • (1997) Acta Diabetologica , vol.34 , Issue.4 , pp. 245-248
    • Honkola, A.1    Forsen, T.2    Eriksson, J.3
  • 15
    • 80051799477 scopus 로고    scopus 로고
    • The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus
    • M. L. M. P. Jorge, V. N. de Oliveira, N. M. Resende et al., "The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus," Metabolism: Clinical and Experimental, vol. 60, no. 9, pp. 1244-1252, 2011.
    • (2011) Metabolism: Clinical and Experimental , vol.60 , Issue.9 , pp. 1244-1252
    • Jorge, M.L.M.P.1    De Oliveira, V.N.2    Resende, N.M.3
  • 16
    • 84896987907 scopus 로고    scopus 로고
    • Evidence for resistance training as a treatment therapy in obesity
    • Article ID 482564
    • B. Strasser and W. Schobersberger, "Evidence for resistance training as a treatment therapy in obesity," Journal of Obesity, vol. 2011, Article ID 482564, 9 pages, 2011.
    • (2011) Journal of Obesity , vol.2011 , pp. 9
    • Strasser, B.1    Schobersberger, W.2
  • 17
    • 80052078622 scopus 로고    scopus 로고
    • The anti-inflammatory effects of exercise: Mechanisms and implications for the prevention and treatment of disease
    • M. Gleeson, N. C. Bishop, D. J. Stensel, M. R. Lindley, S. S. Mastana, and M. A. Nimmo, "The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease," Nature Reviews Immunology, vol. 11, no. 9, pp. 607-610, 2011.
    • (2011) Nature Reviews Immunology , vol.11 , Issue.9 , pp. 607-610
    • Gleeson, M.1    Bishop, N.C.2    Stensel, D.J.3    Lindley, M.R.4    Mastana, S.S.5    Nimmo, M.A.6
  • 18
    • 79751512463 scopus 로고    scopus 로고
    • The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
    • B. Vandanmagsar, Y.-H. Youm, A. Ravussin et al., "The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance," Nature Medicine, vol. 17, no. 2, pp. 179-189, 2011.
    • (2011) Nature Medicine , vol.17 , Issue.2 , pp. 179-189
    • Vandanmagsar, B.1    Youm, Y.-H.2    Ravussin, A.3
  • 19
    • 79954632229 scopus 로고    scopus 로고
    • Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide
    • J. J. Dube, F. Amati, F. G. S. Toledo et al., "Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide," Diabetologia, vol. 54, no. 5, pp. 1147-1156, 2011.
    • (2011) Diabetologia , vol.54 , Issue.5 , pp. 1147-1156
    • Dube, J.J.1    Amati, F.2    Toledo, F.G.S.3
  • 20
    • 77953561361 scopus 로고    scopus 로고
    • Mammalian ceramide synthases
    • M. Levy and A. H. Futerman, "Mammalian ceramide synthases," IUBMB Life, vol. 62, no. 5, pp. 347-356, 2010.
    • (2010) IUBMB Life , vol.62 , Issue.5 , pp. 347-356
    • Levy, M.1    Futerman, A.H.2
  • 21
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • C. M. Taniguchi, B. Emanuelli, and C. R. Kahn, "Critical nodes in signalling pathways: insights into insulin action," Nature Reviews Molecular Cell Biology, vol. 7, no. 2, pp. 85-96, 2006.
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 22
    • 79955932521 scopus 로고    scopus 로고
    • Aerobic training in rats increases skeletal muscle sphingomyelinase and serine palmitoyltransferase activity, while decreasing ceramidase activity
    • A. Bachnio-Zabielska, P. Zabielski, M. Baranowski, and J. Gorski, "Aerobic training in rats increases skeletal muscle sphingomyelinase and serine palmitoyltransferase activity, while decreasing ceramidase activity," Lipids, vol. 46, no. 3, pp. 229-238, 2011.
    • (2011) Lipids , vol.46 , Issue.3 , pp. 229-238
    • Bachnio-Zabielska, A.1    Zabielski, P.2    Baranowski, M.3    Gorski, J.4
  • 23
    • 47949104798 scopus 로고    scopus 로고
    • The role of exercise and PGC1α in inflammation and chronic disease
    • C. Handschin and B. M. Spiegelman, "The role of exercise and PGC1α in inflammation and chronic disease," Nature, vol. 454, no. 7203, pp. 463-469, 2008.
    • (2008) Nature , vol.454 , Issue.7203 , pp. 463-469
    • Handschin, C.1    Spiegelman, B.M.2
  • 24
    • 84909979604 scopus 로고    scopus 로고
    • Integrative biology of exercise
    • J. A. Hawley, M. Hargreaves, M. J. Joyner, and J. R. Zierath, "Integrative biology of exercise," Cell, vol. 159, no. 4, pp. 738-749, 2014.
    • (2014) Cell , vol.159 , Issue.4 , pp. 738-749
    • Hawley, J.A.1    Hargreaves, M.2    Joyner, M.J.3    Zierath, J.R.4
  • 25
    • 38649129910 scopus 로고    scopus 로고
    • Exercise-induced redistribution of T lymphocytes is regulated by adrenergic mechanisms
    • K. Kruger, A. Lechtermann, M. Fobker, K. Volker, and F. C. Mooren, "Exercise-induced redistribution of T lymphocytes is regulated by adrenergic mechanisms," Brain, Behavior, and Immunity, vol. 22, no. 3, pp. 324-338, 2008.
    • (2008) Brain, Behavior, and Immunity , vol.22 , Issue.3 , pp. 324-338
    • Kruger, K.1    Lechtermann, A.2    Fobker, M.3    Volker, K.4    Mooren, F.C.5
  • 26
    • 84893373982 scopus 로고    scopus 로고
    • Functional and muscular adaptations in an experimental model for isometric strength training in mice
    • Article ID e79069
    • K. Kruger, D. K. Gessner, M. Seimetz et al., "Functional and muscular adaptations in an experimental model for isometric strength training in mice," PLoS ONE, vol. 8, no. 11, Article ID e79069, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.11
    • Kruger, K.1    Gessner, D.K.2    Seimetz, M.3
  • 28
    • 82955193688 scopus 로고    scopus 로고
    • Supplementation with L-carnitine downregulates genes of the ubiquitin proteasome system in the skeletal muscle and liver of piglets
    • J. Keller, R. Ringseis, A. Koc, I. Lukas, H. Kluge, and K. Eder, "Supplementation with L-carnitine downregulates genes of the ubiquitin proteasome system in the skeletal muscle and liver of piglets," Animal, vol. 6, no. 1, pp. 70-78, 2012.
    • (2012) Animal , vol.6 , Issue.1 , pp. 70-78
    • Keller, J.1    Ringseis, R.2    Koc, A.3    Lukas, I.4    Kluge, H.5    Eder, K.6
  • 29
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • J. Vandesompele, K. De Preter, F. Pattyn et al., "Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes," Genome Biology, vol. 3, no. 7, pp. 1-11, 2002.
    • (2002) Genome Biology , vol.3 , Issue.7 , pp. 1-11
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 30
    • 7444270716 scopus 로고    scopus 로고
    • High-throughput quantification of phosphatidylcholine and sphingomyelin by electrospray ionization tandem mass spectrometry coupled with isotope correction algorithm
    • G. Liebisch, B. Lieser, J. Rathenberg, W. Drobnik, and G. Schmitz, "High-throughput quantification of phosphatidylcholine and sphingomyelin by electrospray ionization tandem mass spectrometry coupled with isotope correction algorithm," Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, vol. 1686, no. 1-2, pp. 108-117, 2004.
    • (2004) Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids , vol.1686 , Issue.1-2 , pp. 108-117
    • Liebisch, G.1    Lieser, B.2    Rathenberg, J.3    Drobnik, W.4    Schmitz, G.5
  • 31
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • E. G. Bligh and W. J. Dyer, "A rapid method of total lipid extraction and purification," Canadian Journal of Biochemistry and Physiology, vol. 37, no. 8, pp. 911-917, 1959.
    • (1959) Canadian Journal of Biochemistry and Physiology , vol.37 , Issue.8 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 32
    • 0032805993 scopus 로고    scopus 로고
    • Quantitativemeasurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESIMS/ MS)
    • G. Liebisch, W. Drobnik, M. Reil et al., "Quantitativemeasurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESIMS/ MS)," Journal of LipidResearch, vol. 40, no. 8, pp. 1539-1546, 1999.
    • (1999) Journal of LipidResearch , vol.40 , Issue.8 , pp. 1539-1546
    • Liebisch, G.1    Drobnik, W.2    Reil, M.3
  • 35
    • 84873029099 scopus 로고    scopus 로고
    • Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance
    • J. Boon, A. J. Hoy, R. Stark et al., "Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance," Diabetes, vol. 62, no. 2, pp. 401-410, 2013.
    • (2013) Diabetes , vol.62 , Issue.2 , pp. 401-410
    • Boon, J.1    Hoy, A.J.2    Stark, R.3
  • 36
    • 4344614649 scopus 로고    scopus 로고
    • Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
    • S. Stratford, K. L. Hoehn, F. Liu, and S. A. Summers, "Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B," Journal of Biological Chemistry, vol. 279, no. 35, pp. 36608-36615, 2004.
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.35 , pp. 36608-36615
    • Stratford, S.1    Hoehn, K.L.2    Liu, F.3    Summers, S.A.4
  • 38
    • 79955038882 scopus 로고    scopus 로고
    • Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
    • H. Wen, D. Gris, Y. Lei et al., "Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling," Nature Immunology, vol. 12, no. 5, pp. 408-415, 2011.
    • (2011) Nature Immunology , vol.12 , Issue.5 , pp. 408-415
    • Wen, H.1    Gris, D.2    Lei, Y.3
  • 39
    • 84860482342 scopus 로고    scopus 로고
    • A ceramide-centric view of insulin resistance
    • J. A. Chavez and S. A. Summers, "A ceramide-centric view of insulin resistance," Cell Metabolism, vol. 15, no. 5, pp. 585-594, 2012.
    • (2012) Cell Metabolism , vol.15 , Issue.5 , pp. 585-594
    • Chavez, J.A.1    Summers, S.A.2
  • 40
    • 63249117466 scopus 로고    scopus 로고
    • Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance
    • J. M. Haus, S. R. Kashyap, T. Kasumov et al., "Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance," Diabetes, vol. 58, no. 2, pp. 337-343, 2009.
    • (2009) Diabetes , vol.58 , Issue.2 , pp. 337-343
    • Haus, J.M.1    Kashyap, S.R.2    Kasumov, T.3
  • 42
    • 84897115531 scopus 로고    scopus 로고
    • On ceramides, other sphingolipids and impaired glucose homeostasis
    • P. J. Larsen and N. Tennagels, "On ceramides, other sphingolipids and impaired glucose homeostasis," Molecular Metabolism, vol. 3, no. 3, pp. 252-260, 2014.
    • (2014) Molecular Metabolism , vol.3 , Issue.3 , pp. 252-260
    • Larsen, P.J.1    Tennagels, N.2
  • 44
    • 84922168851 scopus 로고    scopus 로고
    • New evidence for the role of ceramide in the development of hepatic insulin resistance
    • Article IDe0116858
    • K. Konstantynowicz-Nowicka, E. Harasim, M. Baranowski, A. Chabowski, and A. Cowart, "New evidence for the role of ceramide in the development of hepatic insulin resistance," PLoS ONE, vol. 10, no. 1, Article IDe0116858, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.1
    • Konstantynowicz-Nowicka, K.1    Harasim, E.2    Baranowski, M.3    Chabowski, A.4    Cowart, A.5
  • 45
    • 84866058762 scopus 로고    scopus 로고
    • Regulation of plasma ceramide levels with fatty acid oversupply: Evidence that the liver detects and secretes de novo synthesised ceramide
    • M. J. Watt, A. C. Barnett, C. R. Bruce, S. Schenk, J. F. Horowitz, and A. J. Hoy, "Regulation of plasma ceramide levels with fatty acid oversupply: evidence that the liver detects and secretes de novo synthesised ceramide," Diabetologia, vol. 55, no. 10, pp. 2741-2746, 2012.
    • (2012) Diabetologia , vol.55 , Issue.10 , pp. 2741-2746
    • Watt, M.J.1    Barnett, A.C.2    Bruce, C.R.3    Schenk, S.4    Horowitz, J.F.5    Hoy, A.J.6
  • 46
    • 33947185206 scopus 로고    scopus 로고
    • Adipose tissue interleukin-18 mRNA and plasma interleukin-18: Effect of obesity and exercise
    • L. Leick, B. Lindegaard, D. Stensvold, P. Plomgaard, B. Saltin, and H. Pilegaard, "Adipose tissue interleukin-18 mRNA and plasma interleukin-18: effect of obesity and exercise," Obesity, vol. 15, no. 2, pp. 356-363, 2007.
    • (2007) Obesity , vol.15 , Issue.2 , pp. 356-363
    • Leick, L.1    Lindegaard, B.2    Stensvold, D.3    Plomgaard, P.4    Saltin, B.5    Pilegaard, H.6
  • 47
    • 33745009509 scopus 로고    scopus 로고
    • Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
    • M. G. Netea, L. A. B. Joosten, E. Lewis et al., "Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance," Nature Medicine, vol. 12, no. 6, pp. 650-656, 2006.
    • (2006) Nature Medicine , vol.12 , Issue.6 , pp. 650-656
    • Netea, M.G.1    Joosten, L.A.B.2    Lewis, E.3
  • 48
    • 84887338975 scopus 로고    scopus 로고
    • Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice
    • B. Lindegaard, V. B. Matthews, C. Brandt et al., "Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice," Diabetes, vol. 62, no. 9, pp. 3064-3074, 2013.
    • (2013) Diabetes , vol.62 , Issue.9 , pp. 3064-3074
    • Lindegaard, B.1    Matthews, V.B.2    Brandt, C.3
  • 49
    • 48449094498 scopus 로고    scopus 로고
    • AMPK and PPARδ agonists are exercise mimetics
    • V. A. Narkar, M. Downes, R. T. Yu et al., "AMPK and PPARδ agonists are exercise mimetics," Cell, vol. 134, no. 3, pp. 405-415, 2008.
    • (2008) Cell , vol.134 , Issue.3 , pp. 405-415
    • Narkar, V.A.1    Downes, M.2    Yu, R.T.3
  • 50
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-α function
    • K. T. Uysal, S. M. Wiesbrock, M. W. Marino, and G. S. Hotamisligil, "Protection from obesity-induced insulin resistance in mice lacking TNF-α function," Nature, vol. 389, no. 6651, pp. 610-614, 1997.
    • (1997) Nature , vol.389 , Issue.6651 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.