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Volumn 11, Issue 10, 2015, Pages 1729-1744

Activation of autophagy in macrophages by pro-resolving lipid mediators

Author keywords

15 epi lipoxin A4; Inflammation; Macrophages resolution; Resolvin D1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BECLIN 1; CHLOROQUINE; LIPID; MAP1LC3 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN; RAPAMYCIN; UBIQUITINATED PROTEIN; ULK1 PROTEIN; UNCLASSIFIED DRUG; CYTOKINE; DOCOSAHEXAENOIC ACID; LIPOXIN; LIPOXIN A; RESOLVIN D1;

EID: 84953863089     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1078958     Document Type: Article
Times cited : (59)

References (75)
  • 2
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • PMID:21785456
    • Mantovani A, Cassatella MA, Costantini C, Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011; 11:519-31; PMID:21785456; http://dx.doi.org/10.1038/nri3024
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 3
    • 84901921079 scopus 로고    scopus 로고
    • Pro-resolving lipidmediators are leads for resolution physiology
    • PMID:24899309
    • Serhan CN. Pro-resolving lipidmediators are leads for resolution physiology. Nature 2014; 510:92-101; PMID:24899309; http://dx.doi.org/10.1038/nature13479
    • (2014) Nature , vol.510 , pp. 92-101
    • Serhan, C.N.1
  • 4
    • 84891892143 scopus 로고    scopus 로고
    • The role of pro-resolution lipid mediators in infectious disease
    • PMID:24400794
    • Russell CD, Schwarze J. The role of pro-resolution lipid mediators in infectious disease. Immunology 2014; 141:166-73; PMID:24400794; http://dx.doi.org/10.1111/imm.12206
    • (2014) Immunology , vol.141 , pp. 166-173
    • Russell, C.D.1    Schwarze, J.2
  • 5
    • 79952941296 scopus 로고    scopus 로고
    • Novel anti-inflammatory-pro-resolving mediators and their receptors
    • PMID:21261595;
    • Serhan CN, Krishnamoorthy S, Recchiuti A, Chiang N. Novel anti-inflammatory-pro-resolving mediators and their receptors. Curr Topics Med Chem 2011; 11:629-47; PMID:21261595; http://dx.doi.org/10.2174/1568026611109060629
    • (2011) Curr Topics Med Chem , vol.11 , pp. 629-647
    • Serhan, C.N.1    Krishnamoorthy, S.2    Recchiuti, A.3    Chiang, N.4
  • 6
    • 84877315077 scopus 로고    scopus 로고
    • Resolution of inflammation: An integrated view
    • PMID:23592557
    • Ortega-Gomez A, Perretti M, Soehnlein O. Resolution of inflammation: an integrated view. EMBO Mol Med 2013; 5:661-74; PMID:23592557; http://dx.doi.org/10.1002/emmm.201202382
    • (2013) EMBO Mol Med , vol.5 , pp. 661-674
    • Ortega-Gomez, A.1    Perretti, M.2    Soehnlein, O.3
  • 7
    • 33947500462 scopus 로고    scopus 로고
    • Resolvins and protectins in the termination program of acute inflammation
    • PMID:17337246
    • Ariel A, Serhan CN. Resolvins and protectins in the termination program of acute inflammation. Trends Immunol 2007; 28:176-83; PMID:17337246; http://dx.doi.org/10.1016/j.it.2007.02.007
    • (2007) Trends Immunol , vol.28 , pp. 176-183
    • Ariel, A.1    Serhan, C.N.2
  • 8
    • 77957942833 scopus 로고    scopus 로고
    • Specialized pro-resolving lipid mediators in the inflammatory response: An update
    • PMID:20708099;
    • Bannenberg G, Serhan CN. Specialized pro-resolving lipid mediators in the inflammatory response: an update. Biochimica et Biophysica Acta 2010; 1801:1260-73; PMID:20708099; http://dx.doi.org/10.1016/j.bbalip.2010.08.002
    • (2010) Biochimica Et Biophysica Acta , vol.1801 , pp. 1260-1273
    • Bannenberg, G.1    Serhan, C.N.2
  • 9
    • 84898663158 scopus 로고    scopus 로고
    • Resolvin D1 stimulates alveolar fluid clearance through alveolar epithelial sodium channel, Na,K-ATPase via ALX/cAMP/PI3K pathway in lipopolysaccharide-induced acute lung injury
    • PMID:24646745
    • Wang Q, Zheng X, Cheng Y, Zhang YL, Wen HX, Tao Z, Li H, Hao Y, Gao Y, Yang LM, et al. Resolvin D1 stimulates alveolar fluid clearance through alveolar epithelial sodium channel, Na,K-ATPase via ALX/cAMP/PI3K pathway in lipopolysaccharide-induced acute lung injury. J Immunol 2014; 192:3765-77; PMID:24646745; http://dx.doi.org/10.4049/jimmunol.1302421
    • (2014) J Immunol , vol.192 , pp. 3765-3777
    • Wang, Q.1    Zheng, X.2    Cheng, Y.3    Zhang, Y.L.4    Wen, H.X.5    Tao, Z.6    Li, H.7    Hao, Y.8    Gao, Y.9    Yang, L.M.10
  • 10
    • 84899151178 scopus 로고    scopus 로고
    • Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin- induced acute kidney injury
    • PMID:24709673
    • Chen J, Shetty S, Zhang P, Gao R, Hu Y, Wang S, Li Z, Fu J. Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin- induced acute kidney injury. Toxicol Appl Pharmacol 2014; 277:118-23; PMID:24709673; http://dx.doi.org/10.1016/j.taap.2014.03.017
    • (2014) Toxicol Appl Pharmacol , vol.277 , pp. 118-123
    • Chen, J.1    Shetty, S.2    Zhang, P.3    Gao, R.4    Hu, Y.5    Wang, S.6    Li, Z.7    Fu, J.8
  • 13
    • 84867753332 scopus 로고    scopus 로고
    • Specific lipid mediator signatures of human phagocytes: Microparticles stimulate macrophage efferocytosis and pro-resolving mediators
    • PMID:22904297
    • Dalli J, Serhan CN. Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators. Blood 2012; 120:e60-72; PMID:22904297; http://dx.doi.org/10.1182/blood-2012-04-423525
    • (2012) Blood , vol.120
    • Dalli, J.1    Serhan, C.N.2
  • 14
    • 81455131791 scopus 로고    scopus 로고
    • Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype
    • PMID:22013115
    • Titos E, Rius B, Gonzalez-Periz A, Lopez-Vicario C, Moran-Salvador E, Martinez-Clemente M, Arroyo V, Claria J. Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype. J Immunol 2011; 187:5408-18; PMID:22013115; http://dx.doi.org/10.4049/jimmunol.1100225
    • (2011) J Immunol , vol.187 , pp. 5408-5418
    • Titos, E.1    Rius, B.2    Gonzalez-Periz, A.3    Lopez-Vicario, C.4    Moran-Salvador, E.5    Martinez-Clemente, M.6    Arroyo, V.7    Claria, J.8
  • 15
    • 84893711468 scopus 로고    scopus 로고
    • Macrophages: Supportive cells for tissue repair and regeneration
    • PMID:24080029
    • Chazaud B. Macrophages: supportive cells for tissue repair and regeneration. Immunobiology 2014; 219:172-8; PMID:24080029; http://dx.doi.org/10.1016/j.imbio.2013.09.001
    • (2014) Immunobiology , vol.219 , pp. 172-178
    • Chazaud, B.1
  • 16
    • 84892576077 scopus 로고    scopus 로고
    • ChoiAM, Ryter SW. Autophagy: A crucial moderator of redox balance, inflammation, and apoptosis in lung disease
    • PMID:23879400
    • Nakahira K, Cloonan SM, Mizumura K, ChoiAM, Ryter SW. Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease. Antioxidants Redox Signaling 2014; 20:474-94; PMID:23879400;http://dx.doi.org/10.1089/ars.2013.5373
    • (2014) Antioxidants Redox Signaling , vol.20 , pp. 474-494
    • Nakahira, K.1    Cloonan, S.M.2    Mizumura, K.3
  • 17
    • 84906901988 scopus 로고    scopus 로고
    • Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways
    • PMID:24457955
    • Delgado ME, Dyck L, Laussmann MA, Rehm M. Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways. Cell Death Dis 2014; 5:e1011; PMID:24457955; http://dx.doi.org/10.1038/cddis.2013.520
    • (2014) Cell Death Dis , vol.5
    • Delgado, M.E.1    Dyck, L.2    Laussmann, M.A.3    Rehm, M.4
  • 18
    • 77953612002 scopus 로고    scopus 로고
    • Lipoxin A4 impairment of apoptotic signaling in macrophages: Implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways
    • PMID:20094061
    • Prieto P, Cuenca J, Traves PG, Fernandez-Velasco M, Martin-Sanz P, Bosca L. Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways. Cell Death Differ 2010; 17:1179-88; PMID:20094061; http://dx.doi.org/10.1038/cdd.2009.220
    • (2010) Cell Death Differ , vol.17 , pp. 1179-1188
    • Prieto, P.1    Cuenca, J.2    Traves, P.G.3    Fernandez-Velasco, M.4    Martin-Sanz, P.5    Bosca, L.6
  • 19
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • PMID:21248839
    • Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011; 469:323-35; PMID:21248839; http://dx.doi.org/10.1038/nature09782
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 20
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • PMID:18305538
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451:1069-75; PMID:18305538; http://dx.doi.org/10.1038/nature06639
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 21
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • PMID:22078875
    • Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011; 147:728-41; PMID:22078875; http://dx.doi.org/10.1016/j.cell.2011.10.026
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 23
    • 53549089861 scopus 로고    scopus 로고
    • Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
    • PMID:18769111
    • Wei Y, Sinha S, Levine B. Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation. Autophagy 2008; 4:949-51; PMID:18769111; http://dx.doi.org/10.4161/auto.6788
    • (2008) Autophagy , vol.4 , pp. 949-951
    • Wei, Y.1    Sinha, S.2    Levine, B.3
  • 25
    • 66449083078 scopus 로고    scopus 로고
    • ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
    • PMID:19258318
    • Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 2009; 284:12297-305; PMID:19258318; http://dx.doi.org/10.1074/jbc.M900573200
    • (2009) J Biol Chem , vol.284 , pp. 12297-12305
    • Ganley, I.G.1    Lam Du, H.2    Wang, J.3    Ding, X.4    Chen, S.5    Jiang, X.6
  • 27
    • 84857802958 scopus 로고    scopus 로고
    • Molecules and their functions in autophagy
    • PMID:22257882
    • Pyo JO, Nah J, Jung YK. Molecules and their functions in autophagy. Exp Mol Med 2012; 44:73-80; PMID:22257882; http://dx.doi.org/10.3858/emm.2012.44.2.029
    • (2012) Exp Mol Med , vol.44 , pp. 73-80
    • Pyo, J.O.1    Nah, J.2    Jung, Y.K.3
  • 28
    • 34548259958 scopus 로고    scopus 로고
    • P62/ SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • PMID:17580304
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T. p62/ SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45; PMID:17580304; http://dx.doi.org/10.1074/jbc.M702824200
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6    Overvatn, A.7    Bjorkoy, G.8    Johansen, T.9
  • 29
    • 59249105964 scopus 로고    scopus 로고
    • Monitoring autophagic degradation of p62/SQSTM1
    • PMID:19200883
    • Bjorkoy G, Lamark T, Pankiv S, Overvatn A, Brech A, Johansen T. Monitoring autophagic degradation of p62/SQSTM1. Methodsn Enzymol 2009; 452:181-97; PMID:19200883; http://dx.doi.org/10.1016/S0076-6879(08)03612-4
    • (2009) Methodsn Enzymol , vol.452 , pp. 181-197
    • Bjorkoy, G.1    Lamark, T.2    Pankiv, S.3    Overvatn, A.4    Brech, A.5    Johansen, T.6
  • 30
    • 84912528393 scopus 로고    scopus 로고
    • Tee AR. MTOR and autophagy: A dynamic relationship governed by nutrients and energy
    • PMID:25158238
    • Dunlop EA, Tee AR. mTOR and autophagy: a dynamic relationship governed by nutrients and energy. Semin cell Dev Biol 2014; 36:121-9; PMID:25158238
    • (2014) Semin Cell Dev Biol , vol.36 , pp. 121-129
    • Dunlop, E.A.1
  • 31
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • PMID:12040186
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296:1655-7; PMID:12040186; http://dx.doi.org/10.1126/science.296.5573.1655
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 36
    • 77953601881 scopus 로고    scopus 로고
    • Regulation of innate immune responses by autophagy-related proteins
    • PMID:20548099
    • Saitoh T, Akira S. Regulation of innate immune responses by autophagy-related proteins. J Cell Biol 2010; 189:925-35; PMID:20548099; http://dx.doi.org/10.1083/jcb.201002021
    • (2010) J Cell Biol , vol.189 , pp. 925-935
    • Saitoh, T.1    Akira, S.2
  • 37
    • 84898788382 scopus 로고    scopus 로고
    • Resolvin D1 promotes the interleukin-4- induced alternative activation in BV-2 microglial cells
    • PMID:24708771
    • Li L, Wu Y, Wang Y, Wu J, Song L, Xian W, Yuan S, Pei L, Shang Y. Resolvin D1 promotes the interleukin-4- induced alternative activation in BV-2 microglial cells. J Neuroinflammation 2014; 11:72; PMID:24708771; http://dx.doi.org/10.1186/1742-2094-11-72
    • (2014) J Neuroinflammation , vol.11 , pp. 72
    • Li, L.1    Wu, Y.2    Wang, Y.3    Wu, J.4    Song, L.5    Xian, W.6    Yuan, S.7    Pei, L.8    Shang, Y.9
  • 38
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • PMID:15528435
    • Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science 2004; 306:990-5; PMID:15528435; http://dx.doi.org/10.1126/science.1099993
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 39
    • 8044257699 scopus 로고    scopus 로고
    • The phosphatidylinositol 3- kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
    • PMID:9030745
    • Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelarova H, Meijer AJ. The phosphatidylinositol 3- kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Euro J Biochem/ FEBS 1997; 243:240-6; PMID:9030745; http://dx.doi.org/10.1111/j.1432-1033.1997.0240a.x
    • (1997) Euro J Biochem/ FEBS , vol.243 , pp. 240-246
    • Blommaart, E.F.1    Krause, U.2    Schellens, J.P.3    Vreeling-Sindelarova, H.4    Meijer, A.J.5
  • 40
  • 41
    • 33746166864 scopus 로고    scopus 로고
    • Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
    • PMID:16818664
    • Corcelle E, Nebout M, Bekri S, Gauthier N, Hofman P, Poujeol P, Fenichel P, Mograbi B. Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity. Cancer Res 2006; 66:6861-70; PMID:16818664; http://dx.doi.org/10.1158/0008-5472.CAN-05-3557
    • (2006) Cancer Res , vol.66 , pp. 6861-6870
    • Corcelle, E.1    Nebout, M.2    Bekri, S.3    Gauthier, N.4    Hofman, P.5    Poujeol, P.6    Fenichel, P.7    Mograbi, B.8
  • 42
    • 84919702335 scopus 로고    scopus 로고
    • Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway
    • PMID:25246560
    • Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I. Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. Proc Natl Acad Sci U S A 2014; 111:14530-5; PMID:25246560; http://dx.doi.org/10.1073/pnas.1410851111
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 14530-14535
    • Fredman, G.1    Ozcan, L.2    Spolitu, S.3    Hellmann, J.4    Spite, M.5    Backs, J.6    Tabas, I.7
  • 43
    • 77449097856 scopus 로고    scopus 로고
    • Resolvin E1 receptor activation signals phosphorylation and phagocytosis
    • PMID:19906641
    • Ohira T, Arita M, Omori K, Recchiuti A, Van Dyke TE, Serhan CN. Resolvin E1 receptor activation signals phosphorylation and phagocytosis. J Biol Chem 2010; 285:3451-61; PMID:19906641; http://dx.doi.org/10.1074/jbc.M109.044131
    • (2010) J Biol Chem , vol.285 , pp. 3451-3461
    • Ohira, T.1    Arita, M.2    Omori, K.3    Recchiuti, A.4    Van Dyke, T.E.5    Serhan, C.N.6
  • 44
    • 78649338158 scopus 로고    scopus 로고
    • FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis
    • PMID:20570963
    • Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C. FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J: Off Pub Federat Am Soc Exp Biol 2010; 24:4240-9; PMID:20570963; http://dx.doi.org/10.1096/fj.10-159913
    • (2010) FASEB J: Off Pub Federat am Soc Exp Biol , vol.24 , pp. 4240-4249
    • Maderna, P.1    Cottell, D.C.2    Toivonen, T.3    Dufton, N.4    Dalli, J.5    Perretti, M.6    Godson, C.7
  • 45
    • 70350127334 scopus 로고    scopus 로고
    • Lipoxins: Resolutionary road
    • PMID:19785661
    • Maderna P, Godson C. Lipoxins: resolutionary road. Brit J Pharmacol 2009; 158:947-59; PMID:19785661; http://dx.doi.org/10.1111/j.1476-5381.2009.00386.x
    • (2009) Brit J Pharmacol , vol.158 , pp. 947-959
    • Maderna, P.1    Godson, C.2
  • 46
    • 84884340814 scopus 로고    scopus 로고
    • Autophagy regulates phagocytosis by modulating the expression of scavenger receptors
    • PMID:24035364
    • Bonilla DL, Bhattacharya A, Sha Y, Xu Y, Xiang Q, Kan A, Jagannath C, Komatsu M, Eissa NT. Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. Immunity 2013; 39:537-47; PMID:24035364; http://dx.doi.org/10.1016/j.immuni.2013.08.026
    • (2013) Immunity , vol.39 , pp. 537-547
    • Bonilla, D.L.1    Bhattacharya, A.2    Sha, Y.3    Xu, Y.4    Xiang, Q.5    Kan, A.6    Jagannath, C.7    Komatsu, M.8    Eissa, N.T.9
  • 47
    • 10344262564 scopus 로고    scopus 로고
    • Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
    • PMID:15558033
    • Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, Tsujimoto Y. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6:1221-8; PMID:15558033; http://dx.doi.org/10.1038/ncb1192
    • (2004) Nat Cell Biol , vol.6 , pp. 1221-1228
    • Shimizu, S.1    Kanaseki, T.2    Mizushima, N.3    Mizuta, T.4    Arakawa-Kobayashi, S.5    Thompson, C.B.6    Tsujimoto, Y.7
  • 48
    • 84902125387 scopus 로고    scopus 로고
    • Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak
    • PMID:24912196
    • Lindqvist LM, Heinlein M, Huang DC, Vaux DL. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak. Proc Natl Acad Sci U S A 2014; 111:8512-7; PMID:24912196; http://dx.doi.org/10.1073/pnas.1406425111
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 8512-8517
    • Lindqvist, L.M.1    Heinlein, M.2    Huang, D.C.3    Vaux, D.L.4
  • 49
    • 84884634690 scopus 로고    scopus 로고
    • Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: Autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
    • PMID:24059496
    • Sarkar S. Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. Biochem Soc Trans 2013; 41:1103-30; PMID:24059496; http://dx.doi.org/10.1042/BST20130134
    • (2013) Biochem Soc Trans , vol.41 , pp. 1103-1130
    • Sarkar, S.1
  • 50
    • 77954898129 scopus 로고    scopus 로고
    • A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions
    • PMID:20627085
    • Lipinski MM, Hoffman G, Ng A, Zhou W, Py BF, Hsu E, Liu X, Eisenberg J, Liu J, Blenis J, et al. A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions. Dev Cell 2010; 18:1041-52; PMID:20627085; http://dx.doi.org/10.1016/j.devcel.2010.05.005
    • (2010) Dev Cell , vol.18 , pp. 1041-1052
    • Lipinski, M.M.1    Hoffman, G.2    Ng, A.3    Zhou, W.4    Py, B.F.5    Hsu, E.6    Liu, X.7    Eisenberg, J.8    Liu, J.9    Blenis, J.10
  • 51
    • 44949237240 scopus 로고    scopus 로고
    • JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
    • PMID:18570871
    • Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30:678-88; PMID:18570871; http://dx.doi.org/10.1016/j.molcel.2008.06.001
    • (2008) Mol Cell , vol.30 , pp. 678-688
    • Wei, Y.1    Pattingre, S.2    Sinha, S.3    Bassik, M.4    Levine, B.5
  • 52
    • 49549123183 scopus 로고    scopus 로고
    • Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factoralpha- induced cell death in MCF-7 cells
    • PMID:18266953
    • Sivaprasad U, Basu A. Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factoralpha- induced cell death in MCF-7 cells. J Cell Mol Med 2008; 12:1265-71; PMID:18266953; http://dx.doi.org/10.1111/j.1582-4934.2008.00282.x
    • (2008) J Cell Mol Med , vol.12 , pp. 1265-1271
    • Sivaprasad, U.1    Basu, A.2
  • 53
    • 0034672063 scopus 로고    scopus 로고
    • Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells
    • PMID:10993892
    • Ogier-Denis E, Pattingre S, El Benna J, Codogno P. Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells. J Biol Chem 2000; 275:39090-5; PMID:10993892; http://dx.doi.org/10.1074/jbc.M006198200
    • (2000) J Biol Chem , vol.275 , pp. 39090-39095
    • Ogier-Denis, E.1    Pattingre, S.2    El Benna, J.3    Codogno, P.4
  • 54
    • 84902051038 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma
    • PMID:24886888
    • Gong K, Zhang Z, Chen Y, Shu HB, Li W. Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma. Euro J Pharmacol 2014; 738C:142-52; PMID:24886888; http://dx.doi.org/10.1016/j.ejphar.2014.05.034
    • (2014) Euro J Pharmacol , vol.738C , pp. 142-152
    • Gong, K.1    Zhang, Z.2    Chen, Y.3    Shu, H.B.4    Li, W.5
  • 55
    • 84906219165 scopus 로고    scopus 로고
    • Sulforaphane induces autophagy through ERK activation in neuronal cells
    • PMID:24952354
    • Jo C, Kim S, Cho SJ, Choi KJ, Yun SM, Koh YH, Johnson GV, Park SI. Sulforaphane induces autophagy through ERK activation in neuronal cells. FEBS Lett 2014; 588(17):3081-8; PMID:24952354
    • (2014) FEBS Lett , vol.588 , Issue.17 , pp. 3081-3088
    • Jo, C.1    Kim, S.2    Cho, S.J.3    Choi, K.J.4    Yun, S.M.5    Koh, Y.H.6    Johnson, G.V.7    Park, S.I.8
  • 56
    • 84906051999 scopus 로고    scopus 로고
    • Induction of autophagy by Tongxinluo via the MEK/ERK pathway protects human cardiac microvascular endothelial cells from hypoxia/reoxygenation injury
    • PMID:24705173
    • Cui H, Li X, Li N, Qi K, Li Q, Jin C, Zhang Q, Jiang L, Yang Y. Induction of autophagy by Tongxinluo via the MEK/ERK pathway protects human cardiac microvascular endothelial cells from hypoxia/reoxygenation injury. J Cardiovasc Pharmacol 2014; 64(2):180-90; PMID:24705173
    • (2014) J Cardiovasc Pharmacol , vol.64 , Issue.2 , pp. 180-190
    • Cui, H.1    Li, X.2    Li, N.3    Qi, K.4    Li, Q.5    Jin, C.6    Zhang, Q.7    Jiang, L.8    Yang, Y.9
  • 57
    • 79954542852 scopus 로고    scopus 로고
    • Targeting Nrf2 signaling improves bacterial clearance by alveolarmacrophages in patients with COPD and in a mouse model
    • PMID:21490276
    • Harvey CJ, Thimmulappa RK, Sethi S, Kong X, Yarmus L, Brown RH, FellerKopman D, Wise R, Biswal S.Targeting Nrf2 signaling improves bacterial clearance by alveolarmacrophages in patients with COPD and in a mouse model. Sci Trans Med 2011; 3:78ra32; PMID:21490276; http://dx.doi.org/10.1126/scitranslmed.3002042
    • (2011) Sci Trans Med , vol.3
    • Harvey, C.J.1    Thimmulappa, R.K.2    Sethi, S.3    Kong, X.4    Yarmus, L.5    Brown, R.H.6    Fellerkopman, D.7    Wise, R.8    Biswal, S.9
  • 60
    • 84861049969 scopus 로고    scopus 로고
    • Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions
    • PMID:22452982
    • Jacquel A, Obba S, Boyer L, Dufies M, Robert G, Gounon P, Lemichez E, Luciano F, Solary E, Auberger P. Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions. Blood 2012; 119:4527-31; PMID:22452982; http://dx.doi.org/10.1182/blood-2011-11-392167
    • (2012) Blood , vol.119 , pp. 4527-4531
    • Jacquel, A.1    Obba, S.2    Boyer, L.3    Dufies, M.4    Robert, G.5    Gounon, P.6    Lemichez, E.7    Luciano, F.8    Solary, E.9    Auberger, P.10
  • 61
    • 84886797274 scopus 로고    scopus 로고
    • Autophagy in infection, inflammation and immunity
    • PMID:24064518
    • Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nat Rev Immunol 2013; 13:722-37; PMID:24064518; http://dx.doi.org/10.1038/nri3532
    • (2013) Nat Rev Immunol , vol.13 , pp. 722-737
    • Deretic, V.1    Saitoh, T.2    Akira, S.3
  • 62
    • 41949101594 scopus 로고    scopus 로고
    • Toll-like receptors control autophagy
    • PMID:18337753
    • Delgado MA, Elmaoued RA, Davis AS, Kyei G, Deretic V. Toll-like receptors control autophagy. EMBO J 2008; 27:1110-21; PMID:18337753; http://dx.doi.org/10.1038/emboj.2008.31
    • (2008) EMBO J , vol.27 , pp. 1110-1121
    • Delgado, M.A.1    Elmaoued, R.A.2    Davis, A.S.3    Kyei, G.4    Deretic, V.5
  • 64
    • 73849151394 scopus 로고    scopus 로고
    • NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
    • PMID:19966812
    • Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, Ferguson DJ, Campbell BJ, Jewell D, Simmons A. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 2010; 16:90-7; PMID:19966812; http://dx.doi.org/10.1038/nm.2069
    • (2010) Nat Med , vol.16 , pp. 90-97
    • Cooney, R.1    Baker, J.2    Brain, O.3    Danis, B.4    Pichulik, T.5    Allan, P.6    Ferguson, D.J.7    Campbell, B.J.8    Jewell, D.9    Simmons, A.10
  • 65
    • 84953862047 scopus 로고    scopus 로고
    • The role of the autophagy in myocardial ischemia/reperfusion injury
    • PMID:25593583
    • Ma S, Wang Y, Chen Y, Cao F. The role of the autophagy in myocardial ischemia/reperfusion injury. Biochimica et Biophysica Acta 2014; 1(4):338-48; PMID:25593583
    • (2014) Biochimica Et Biophysica Acta , vol.1 , Issue.4 , pp. 338-348
    • Ma, S.1    Wang, Y.2    Chen, Y.3    Cao, F.4
  • 66
    • 84919786967 scopus 로고    scopus 로고
    • Autophagy and oxidative stress in cardiovascular diseases
    • PMID:24834848
    • Mei Y, Thompson MD, Cohen RA, Tong X. Autophagy and oxidative stress in cardiovascular diseases. Biochimica et Biophysica Acta 2014; 1852(2):243-51; PMID:24834848
    • (2014) Biochimica Et Biophysica Acta , vol.1852 , Issue.2 , pp. 243-251
    • Mei, Y.1    Thompson, M.D.2    Cohen, R.A.3    Tong, X.4
  • 67
    • 84899474879 scopus 로고    scopus 로고
    • Self-eating in the plaque: What macrophage autophagy reveals about atherosclerosis
    • PMID:24746519
    • Sergin I, Razani B. Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis. Trends Endocrinol Metab: TEM 2014; 25:225-34; PMID:24746519; http://dx.doi.org/10.1016/j.tem.2014.03.010
    • (2014) Trends Endocrinol Metab: TEM , vol.25 , pp. 225-234
    • Sergin, I.1    Razani, B.2
  • 68
    • 84904721826 scopus 로고    scopus 로고
    • Autophagy in adipose tissue and the beta cell: Implications for obesity and diabetes
    • PMID:24795087
    • Stienstra R, Haim Y, Riahi Y, Netea M, Rudich A, Leibowitz G. Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes. Diabetologia 2014; 57(8):1505-16; PMID:24795087
    • (2014) Diabetologia , vol.57 , Issue.8 , pp. 1505-1516
    • Stienstra, R.1    Haim, Y.2    Riahi, Y.3    Netea, M.4    Rudich, A.5    Leibowitz, G.6
  • 69
    • 84881025556 scopus 로고    scopus 로고
    • Impaired autophagy and APP processing in Alzheimer’s disease: The potential role of Beclin 1 interactome
    • PMID:23827971
    • Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M. Impaired autophagy and APP processing in Alzheimer’s disease: the potential role of Beclin 1 interactome. Prog Neurobiol 2013; 106-107:33-54; PMID:23827971; http://dx.doi.org/10.1016/j.pneurobio.2013.06.002
    • (2013) Prog Neurobiol , vol.106-107 , pp. 33-54
    • Salminen, A.1    Kaarniranta, K.2    Kauppinen, A.3    Ojala, J.4    Haapasalo, A.5    Soininen, H.6    Hiltunen, M.7
  • 70
    • 84879232282 scopus 로고    scopus 로고
    • Autophagy failure in Alzheimer’s disease and the role of defective lysosomal acidification
    • PMID:23773064
    • Wolfe DM, Lee JH, Kumar A, Lee S, Orenstein SJ, Nixon RA. Autophagy failure in Alzheimer’s disease and the role of defective lysosomal acidification. Euro J Neurosci 2013; 37:1949-61; PMID:23773064; http://dx.doi.org/10.1111/ejn.12169
    • (2013) Euro J Neurosci , vol.37 , pp. 1949-1961
    • Wolfe, D.M.1    Lee, J.H.2    Kumar, A.3    Lee, S.4    Orenstein, S.J.5    Nixon, R.A.6
  • 71
    • 84901999801 scopus 로고    scopus 로고
    • Cytotoxic autophagy in cancer therapy
    • PMID:24905404
    • Sharma K, Le N, Alotaibi M, Gewirtz DA. Cytotoxic autophagy in cancer therapy. Int J Mol Sci 2014; 15:10034-51; PMID:24905404; http://dx.doi.org/10.3390/ijms150610034
    • (2014) Int J Mol Sci , vol.15 , pp. 10034-10051
    • Sharma, K.1    Le, N.2    Alotaibi, M.3    Gewirtz, D.A.4
  • 72
    • 84899502960 scopus 로고    scopus 로고
    • Autophagy and cancer therapy
    • PMID:24574520
    • Thorburn A, Thamm DH, Gustafson DL. Autophagy and cancer therapy. Mol Pharmacol 2014; 85:830-8; PMID:24574520; http://dx.doi.org/10.1124/mol.114.091850
    • (2014) Mol Pharmacol , vol.85 , pp. 830-838
    • Thorburn, A.1    Thamm, D.H.2    Gustafson, D.L.3
  • 73
    • 84893825919 scopus 로고    scopus 로고
    • The four faces of autophagy: Implications for cancer therapy
    • PMID:24459182
    • Gewirtz DA. The four faces of autophagy: implications for cancer therapy. Cancer Res 2014; 74:647-51; PMID:24459182; http://dx.doi.org/10.1158/0008-5472.CAN-13-2966
    • (2014) Cancer Res , vol.74 , pp. 647-651
    • Gewirtz, D.A.1
  • 74
    • 0034746792 scopus 로고    scopus 로고
    • PenningtonDJ,Otto F, Parker PJ,OwenMJ, Bosca L. Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection
    • PMID:11696589
    • Castrillo A, PenningtonDJ,Otto F, Parker PJ,OwenMJ, Bosca L. Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection. J Exp Med 2001; 194:1231-42; PMID:11696589; http://dx.doi.org/10.1084/jem.194.9.1231
    • (2001) J Exp Med , vol.194 , pp. 1231-1242
    • Castrillo, A.1
  • 75
    • 79955163875 scopus 로고    scopus 로고
    • A practical guide to evaluating colocalization in biological microscopy
    • PMID:21209361
    • Dunn KW, Kamocka MM, McDonald JH. A practical guide to evaluating colocalization in biological microscopy. Am J Physiol Cell Physiol 2011; 300:C723-42; PMID:21209361; http://dx.doi.org/10.1152/ajpcell.00462.2010
    • (2011) Am J Physiol Cell Physiol , vol.300
    • Dunn, K.W.1    Kamocka, M.M.2    McDonald, J.H.3


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