Resolvin D1 Limits 5-lipoxygenase nuclear localization and Leukotriene B4 synthesis by inhibiting a calciumactivated kinase pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 40, 2014, Pages 14530-14535

  Fredman, Gabrielle ^a   Ozcan, Lale ^a   Spolitu, Stefano ^a   Hellmann, Jason ^b   Spite, Matthew ^b   Backs, Johannes ^c   Tabas, Ira ^a   Perretti, Mauro ^d  

^a NewYork Presbyterian Hospital   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; DOCOSAHEXAENOIC ACID; FORMYLPEPTIDE RECEPTOR LIKE 1; LEUKOTRIENE A4; LEUKOTRIENE B4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; RESOLVIN D1; SERINE; UNCLASSIFIED DRUG; ARACHIDONIC ACID; FORMYL PEPTIDE RECEPTOR 2, MOUSE; FORMYLPEPTIDE RECEPTOR; FPR1 PROTEIN, MOUSE; MAP-KINASE-ACTIVATED KINASE 2; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CALCIUM CELL LEVEL; CELL NUCLEUS; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; ZYMOSAN-INDUCED PERITONITIS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; IMMUNOBLOTTING; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PHOSPHORYLATION; TRANSGENIC MOUSE;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL NUCLEUS; CELLS, CULTURED; CYTOPLASM; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOTRIENE B4; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, FORMYL PEPTIDE; SERINE;

EID: 84919702335     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1410851111     Document Type: Article

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