Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 1, 2016, Pages 152-157

  Marsden, Clare D ^a   Vecchyo, Diego Ortega Del ^a   O'Brien, Dennis P ^b   Taylor, Jeremy F ^b   Ramirez, Oscar ^c   Vilà, Carles ^d   Marques Bonet, Tomas ^c,e   Schnabel, Robert D ^b   Wayne, Robert K ^a   Lohmueller, Kirk E ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c CSIC   (Spain)

^d DEPARTMENT OF CONSERVATION BIOLOGY   (Spain)

^e Centro Nacional de Analisis Genomico   (Spain)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bottleneck; Deleterious mutations; Domestication; Selective sweep

Indexed keywords

ANIMAL; DOG; DOG DISEASE; DOMESTIC ANIMAL; ENDANGERED SPECIES; GENETIC SELECTION; GENETIC VARIATION; GENETICS; GENOME; HETEROZYGOTE; INBREEDING; INFORMATION PROCESSING; POPULATION DENSITY; SELECTIVE BREEDING; WOLF;

ANIMALS; ANIMALS, DOMESTIC; DATASETS AS TOPIC; DOG DISEASES; DOGS; ENDANGERED SPECIES; GENETIC VARIATION; GENOME; HETEROZYGOTE; INBREEDING; POPULATION DENSITY; SELECTION, GENETIC; SELECTIVE BREEDING; WOLVES;

EID: 84953215554     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1512501113     Document Type: Article

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