Synthesis and bioactivity of novel triazole incorporated benzothiazinone derivatives as antitubercular and antioxidant agent

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 2, 2016, Pages 561-569

  Shaikh, Mubarak H ^a   Subhedar, Dnyaneshwar D ^a   Arkile, Manisha ^b   Khedkar, Vijay M ^b,c   Jadhav, Nandadeep ^b   Sarkar, Dhiman ^b   Shingate, Bapurao B ^a  

^a DR BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY   (India)

^b NATIONAL CHEMICAL LABORATORY   (India)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

1,2,3 Triazole; ADME prediction; Antioxidant; Antitubercular; Docking study

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BENZOTHIAZINE DERIVATIVE; ISONIAZID; PACLITAXEL; RIFAMPICIN; TUBERCULOSTATIC AGENT; ALCOHOL DEHYDROGENASE; BACTERIAL PROTEIN; DPRE1 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; SCAVENGER; THIAZINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CLICK CHEMISTRY; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; LUNG ADENOCARCINOMA; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; OXIDATIVE STRESS; STATIC ELECTRICITY; TUBERCULOSIS; UTERINE CERVIX CANCER; CHEMISTRY; DRUG EFFECTS; HYDROGEN BOND; SYNTHESIS; TUMOR CELL LINE;

ALCOHOL OXIDOREDUCTASES; ANTINEOPLASTIC AGENTS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CELL LINE, TUMOR; CLICK CHEMISTRY; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN BONDING; MOLECULAR DOCKING SIMULATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; THIAZINES; TRIAZOLES;

EID: 84952987511     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.11.071     Document Type: Article

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