메뉴 건너뛰기




Volumn 17, Issue 5, 2012, Pages 5882-5892

Synthesis of 1,2,3-triazole derivatives and in Vitro antifungal evaluation on Candida strains

Author keywords

1,2,3 triazoles; Antifungal activity; Candida spp.; Click chemistry

Indexed keywords

ANTIFUNGAL AGENT; AZIDE; MICONAZOLE; PROPANOL; TRIAZOLE DERIVATIVE;

EID: 84861488402     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17055882     Document Type: Article
Times cited : (72)

References (33)
  • 1
    • 77950215343 scopus 로고    scopus 로고
    • Candidosis a new challenge
    • Lopez-Martinez, R. Candidosis, a new challenge. Clin. Dermatol. 2010, 6, 178-184.
    • (2010) Clin. Dermatol. , vol.6 , pp. 178-184
    • Lopez-Martinez, R.1
  • 3
    • 0035132479 scopus 로고    scopus 로고
    • Emergence of methicillin-resistant staphylococcus aureus with intermediate lycopeptide resistance: Clinical significance and treatment options
    • Rybak, M.J.; Akins, R.L. Emergence of methicillin-resistant Staphylococcus aureus with intermediate lycopeptide resistance: clinical significance and treatment options. Drugs 2001, 6, 1-7.
    • (2001) Drugs , vol.6 , pp. 1-7
    • Rybak, M.J.1    Akins, R.L.2
  • 5
    • 33748743441 scopus 로고    scopus 로고
    • Synthesis and qsar studies of novel triazole compounds containing thioamide as potential antifungal agents
    • Wei, Q.L.; Zhang, S.S.; Gao, J.; Li, W.H.; Xu, L.Z.; Yu, Z.G. Synthesis and QSAR studies of novel triazole compounds containing thioamide as potential antifungal agents. Bioorg. Med. Chem. 2006, 14, 7146-7153.
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 7146-7153
    • Wei, Q.L.1    Zhang, S.S.2    Gao, J.3    Li, W.H.4    Xu, L.Z.5    Yu, Z.G.6
  • 6
    • 67749102126 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of a novel triazole, isavuconazole: Mathematical modeling, importance of tissue concentrations, and impact of immune status on antifungal effect
    • Warn, P.A.; Sharp, A.; Parmar, A.; Majithiya, J.; Denning, D.W.; Hope, W.W. Pharmacokinetics and pharmacodynamics of a novel triazole, isavuconazole: Mathematical modeling, importance of tissue concentrations, and impact of immune status on antifungal effect. Antimicrob. Agents Chemother. 2009, 53, 3453-3461.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 3453-3461
    • Warn, P.A.1    Sharp, A.2    Parmar, A.3    Majithiya, J.4    Denning, D.W.5    Hope, W.W.6
  • 7
    • 84859445044 scopus 로고    scopus 로고
    • New triazole derivatives as antifungal agents: Synthesis via click reaction, in vitro evaluation and molecular docking studies
    • Zou, Y.; Zhao, Q.; Liao, J.; Hua, H.; Yu, S.; Chai, X.; Xu, M.; Wua, Q. New triazole derivatives as antifungal agents: Synthesis via click reaction, in vitro evaluation and molecular docking studies. Bioorg. Med. Chem. Lett. 2012, 22, 2959-2962.
    • (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 2959-2962
    • Zou, Y.1    Zhao, Q.2    Liao, J.3    Hua, H.4    Yu, S.5    Chai, X.6    Xu, M.7    Wua, Q.8
  • 8
    • 0035663918 scopus 로고    scopus 로고
    • Synthesis and antimicrobial activity of some 1,2,4-triazole-3- mercaptoacetic acid derivatives
    • Ulusoy, N.; Gursoy, A.; Otuk, G. Synthesis and antimicrobial activity of some 1,2,4-triazole-3- mercaptoacetic acid derivatives. Farmaco 2001, 56, 947-952.
    • (2001) Farmaco , vol.56 , pp. 947-952
    • Ulusoy, N.1    Gursoy, A.2    Otuk, G.3
  • 9
    • 33644644217 scopus 로고    scopus 로고
    • Synthesis and biological activities of new 1,2,4-triazol-3-one derivatives
    • Demirbas, N.; Demirbas, A.; Karaoglu, S.A. Synthesis and biological activities of new 1,2,4-triazol-3-one derivatives. Bioorg. Khim. 2005, 31, 430-440.
    • (2005) Bioorg. Khim. , vol.31 , pp. 430-440
    • Demirbas, N.1    Demirbas, A.2    Karaoglu, S.A.3
  • 10
    • 56949104357 scopus 로고    scopus 로고
    • Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of co(ii), ni(ii) and cu(ii) complexes with 1,2,4-triazole schiff bases
    • Bagihalli, G.B.; Avaji, P.G.; Patil, S.A.; Badami, P.S. Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases. Eur. J. Med. Chem. 2008, 43, 2639-2649.
    • (2008) Eur. J. Med. Chem. , vol.43 , pp. 2639-2649
    • Bagihalli, G.B.1    Avaji, P.G.2    Patil, S.A.3    Badami, P.S.4
  • 11
    • 33749238697 scopus 로고    scopus 로고
    • Synthesis and biological activity of schiff and mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety
    • Karthikeyan, M.S.; Prasad, D.J.; Poojary, B.; Bhat, K.S.; Holla, B.S.; Kumari, N.S. Synthesis and biological activity of Schiff and Mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety. Bioorg. Med. Chem. 2006, 14, 7482-7489.
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 7482-7489
    • Karthikeyan, M.S.1    Prasad, D.J.2    Poojary, B.3    Bhat, K.S.4    Holla, B.S.5    Kumari, N.S.6
  • 12
    • 0037294865 scopus 로고    scopus 로고
    • Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives
    • Dabak, K.; Sezer, O.; Akar, A.; Anac, O. Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives. Eur. J. Med. Chem. 2003, 38, 215-218.
    • (2003) Eur. J. Med. Chem. , vol.38 , pp. 215-218
    • Dabak, K.1    Sezer, O.2    Akar, A.3    Anac, O.4
  • 13
  • 14
    • 0347131149 scopus 로고    scopus 로고
    • In vitro study of some medicinally important mannich bases derived from antitubercular agent
    • Joshi, S.; Khosla, N.; Tiwari, P. In vitro study of some medicinally important Mannich bases derived from antitubercular agent. Bioorg. Med. Chem. 2004, 12, 571-576.
    • (2004) Bioorg. Med. Chem. , vol.12 , pp. 571-576
    • Joshi, S.1    Khosla, N.2    Tiwari, P.3
  • 15
    • 84859429130 scopus 로고    scopus 로고
    • Aglycone-focused randomization of 2-difluoromethylphenyltype sialoside suicide substrates for neuraminidases
    • Kai, H.; Hinou, H.; Nishimura, S.-I. Aglycone-focused randomization of 2-difluoromethylphenyltype sialoside suicide substrates for neuraminidases. Bioorg. Med. Chem. 2012, 20, 2739-2746.
    • (2012) Bioorg. Med. Chem. , vol.20 , pp. 2739-2746
    • Kai, H.1    Hinou, H.2    Nishimura, S.-I.3
  • 16
    • 0043158805 scopus 로고    scopus 로고
    • Synthesis, characterization and anticancer activity studies on some mannich bases derived from 1,2,4-triazoles
    • Holla, B.S.; Veerendra, B.; Shivananda, M.K.; Poojary, B. Synthesis, characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles. Eur. J. Med. Chem. 2003, 38, 759-767.
    • (2003) Eur. J. Med. Chem. , vol.38 , pp. 759-767
    • Holla, B.S.1    Veerendra, B.2    Shivananda, M.K.3    Poojary, B.4
  • 17
  • 18
    • 0033617496 scopus 로고    scopus 로고
    • Synthesis and analgesic activity of some triazoles and triazolo-thiadiazines
    • Turan-Zitouni, G.; Kaplancikli, Z.A.; Erol, K.; Kilic, F.S. Synthesis and analgesic activity of some triazoles and triazolo-thiadiazines. Farmaco 1999, 54, 218-223.
    • (1999) Farmaco , vol.54 , pp. 218-223
    • Turan-Zitouni, G.1    Kaplancikli, Z.A.2    Erol, K.3    Kilic, F.S.4
  • 19
    • 84862777493 scopus 로고    scopus 로고
    • Design synthesis and biological evaluation of novel 2-methylpyrimidine-4- ylamine derivatives as inhibitors of escherichia coli pyruvate dehydrogenase complex e1
    • He, J.; Feng, L.; Li, J.; Tao, R.; Wang, F.; Liao, X.; Sun, Q.; Long, Q.; Ren, Y.; Wan, J.; He, H. Design, synthesis and biological evaluation of novel 2-methylpyrimidine-4-ylamine derivatives as inhibitors of Escherichia coli pyruvate dehydrogenase complex E1. Bioorg. Med. Chem 2012, 20, 1665-1670.
    • (2012) Bioorg. Med. Chem , vol.20 , pp. 1665-1670
    • He, J.1    Feng, L.2    Li, J.3    Tao, R.4    Wang, F.5    Liao, X.6    Sun, Q.7    Long, Q.8    Ren, Y.9    Wan, J.10    He, H.11
  • 20
    • 84856681904 scopus 로고    scopus 로고
    • Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold
    • Oh, K.; Yamada, K.; Asami, T.; Yoshizawa, Y. Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold. Bioorg. Med. Chem. Lett. 2012, 22, 1625-1628.
    • (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 1625-1628
    • Oh, K.1    Yamada, K.2    Asami, T.3    Yoshizawa, Y.4
  • 21
    • 15244344612 scopus 로고    scopus 로고
    • Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe
    • Malolanarasimhan, K.; Lai, C.C.; Kelley, J.A.; Iaccarino, L.; Reynolds, D.; Young, H.A.; Marquez, V.E. Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe. Bioorg. Med. Chem. 2005, 13, 2717-2722.
    • (2005) Bioorg. Med. Chem. , vol.13 , pp. 2717-2722
    • Malolanarasimhan, K.1    Lai, C.C.2    Kelley, J.A.3    Iaccarino, L.4    Reynolds, D.5    Young, H.A.6    Marquez, V.E.7
  • 22
    • 33744966628 scopus 로고    scopus 로고
    • A new solvent system for efficient synthesis of 1,2,3-triazoles
    • Lee, B.Y.; Park, S.R.; Jeon, H.B.; Kim, K.S. A new solvent system for efficient synthesis of 1,2,3-triazoles. Tetrahedron Lett. 2006, 47, 5105-5109.
    • (2006) Tetrahedron Lett. , vol.47 , pp. 5105-5109
    • Lee, B.Y.1    Park, S.R.2    Jeon, H.B.3    Kim, K.S.4
  • 25
    • 67650462258 scopus 로고    scopus 로고
    • Synthesis and cytotoxic profile of glycosyl triazole linked to 1,2,4-oxadiazole moiety at c-5 through a straight-chain carbon and oxygen atoms
    • dos Anjos, J.V.; Neves Filho, R.A.W.; Nascimento, S.C.; Srivastava, R.M.; Melo, S.J.; Sinou, D. Synthesis and cytotoxic profile of glycosyl triazole linked to 1,2,4-oxadiazole moiety at C-5 through a straight-chain carbon and oxygen atoms. Eur. J. Med. Chem. 2009, 44, 3571-3576.
    • (2009) Eur. J. Med. Chem. , vol.44 , pp. 3571-3576
    • Dos Anjos, J.V.1    Neves Filho, R.A.W.2    Nascimento, S.C.3    Srivastava, R.M.4    Melo, S.J.5    Sinou, D.6
  • 26
    • 70349214806 scopus 로고    scopus 로고
    • Discovery of highly potent novel antifungal azoles by structure-based rational design
    • Wang, W.; Sheng, C.; Che, X.; Ji, H.; Cao, Y.; Miao, Z.; Yao, J.; Zhang, W. Discovery of highly potent novel antifungal azoles by structure-based rational design. Bioorg. Med. Chem. Lett. 2009, 19, 5965-5969.
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 5965-5969
    • Wang, W.1    Sheng, C.2    Che, X.3    Ji, H.4    Cao, Y.5    Miao, Z.6    Yao, J.7    Zhang, W.8
  • 27
    • 78649317458 scopus 로고    scopus 로고
    • Novel conformationally restricted triazole derivatives with potent antifungal activity
    • Wang, W.; Wang, S.; Liu, Y.; Dong, G.; Cao, Y.; Miao, Z.; Yao, J.; Zhang, W.; Sheng, C. Novel conformationally restricted triazole derivatives with potent antifungal activity. Eur. J. Med. Chem. 2010, 45, 6020-6026.
    • (2010) Eur. J. Med. Chem. , vol.45 , pp. 6020-6026
    • Wang, W.1    Wang, S.2    Liu, Y.3    Dong, G.4    Cao, Y.5    Miao, Z.6    Yao, J.7    Zhang, W.8    Sheng, C.9
  • 28
    • 0021048099 scopus 로고
    • A new approach to practical acute toxicity testing
    • Lorke, D. A new approach to practical acute toxicity testing. Arch. Toxicol. 1983, 54, 275-287.
    • (1983) Arch. Toxicol. , vol.54 , pp. 275-287
    • Lorke, D.1
  • 29
    • 0005868279 scopus 로고
    • A method for maintaining phytomonas sepedomica for long periods without transfer
    • Sherf, A.F. A method for maintaining Phytomonas sepedomica for long periods without transfer. Phytopathology 1943, 31, 30-32.
    • (1943) Phytopathology , vol.31 , pp. 30-32
    • Sherf, A.F.1
  • 30
    • 0003503732 scopus 로고    scopus 로고
    • 2nd ed.; Centraalbureau voor Schimmelcultures: Utrecht, The Netherlands and Universitat Rovira i Virgili: Reus, Spain
    • de Hoog, G.S.; Guarro, J.; Gene, J.; Figueras, M.J. Atlas of Clinical Fungi, 2nd ed.; Centraalbureau voor Schimmelcultures: Utrecht, The Netherlands and Universitat Rovira i Virgili: Reus, Spain, 2000; p. 1124.
    • (2000) Atlas of Clinical Fungi , pp. 1124
    • De Hoog, G.S.1    Guarro, J.2    Gene, J.3    Figueras, M.J.4
  • 31
    • 78649474716 scopus 로고    scopus 로고
    • Clinical Laboratory Standards Institute (CLSI). Approved standard-third edition M27-A3; CLSI: Wayne, PA, USA
    • Clinical Laboratory Standards Institute (CLSI). Reference Method for Broth Dilution Testing of Yeasts; Approved standard-third edition M27-A3; CLSI: Wayne, PA, USA, 2008.
    • (2008) Reference Method for Broth Dilution Testing of Yeasts
  • 33
    • 84861500920 scopus 로고    scopus 로고
    • Organisation for Economic Co-operation and Development (OECD). OECD Guideline for Testing of Chemicals: Acute Oral Toxicity-Up-and-Down Procedure; n 425; OECD Publishing: Paris, France
    • Organisation for Economic Co-operation and Development (OECD). OECD Guideline for Testing of Chemicals: Acute Oral Toxicity-Up-and-Down Procedure; n 425; OECD Publishing: Paris, France, 2001.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.