-
1
-
-
77950215343
-
Candidosis a new challenge
-
Lopez-Martinez, R. Candidosis, a new challenge. Clin. Dermatol. 2010, 6, 178-184.
-
(2010)
Clin. Dermatol.
, vol.6
, pp. 178-184
-
-
Lopez-Martinez, R.1
-
3
-
-
0035132479
-
Emergence of methicillin-resistant staphylococcus aureus with intermediate lycopeptide resistance: Clinical significance and treatment options
-
Rybak, M.J.; Akins, R.L. Emergence of methicillin-resistant Staphylococcus aureus with intermediate lycopeptide resistance: clinical significance and treatment options. Drugs 2001, 6, 1-7.
-
(2001)
Drugs
, vol.6
, pp. 1-7
-
-
Rybak, M.J.1
Akins, R.L.2
-
4
-
-
0032960378
-
Current and emerging azole antifungal agents
-
Sheehan, D.J.; Hitchcock, C.A.; Sibley, C.M. Current and emerging azole antifungal agents. Clin. Microbiol. Rev. 1999, 12, 40-79.
-
(1999)
Clin. Microbiol. Rev.
, vol.12
, pp. 40-79
-
-
Sheehan, D.J.1
Hitchcock, C.A.2
Sibley, C.M.3
-
5
-
-
33748743441
-
Synthesis and qsar studies of novel triazole compounds containing thioamide as potential antifungal agents
-
Wei, Q.L.; Zhang, S.S.; Gao, J.; Li, W.H.; Xu, L.Z.; Yu, Z.G. Synthesis and QSAR studies of novel triazole compounds containing thioamide as potential antifungal agents. Bioorg. Med. Chem. 2006, 14, 7146-7153.
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 7146-7153
-
-
Wei, Q.L.1
Zhang, S.S.2
Gao, J.3
Li, W.H.4
Xu, L.Z.5
Yu, Z.G.6
-
6
-
-
67749102126
-
Pharmacokinetics and pharmacodynamics of a novel triazole, isavuconazole: Mathematical modeling, importance of tissue concentrations, and impact of immune status on antifungal effect
-
Warn, P.A.; Sharp, A.; Parmar, A.; Majithiya, J.; Denning, D.W.; Hope, W.W. Pharmacokinetics and pharmacodynamics of a novel triazole, isavuconazole: Mathematical modeling, importance of tissue concentrations, and impact of immune status on antifungal effect. Antimicrob. Agents Chemother. 2009, 53, 3453-3461.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 3453-3461
-
-
Warn, P.A.1
Sharp, A.2
Parmar, A.3
Majithiya, J.4
Denning, D.W.5
Hope, W.W.6
-
7
-
-
84859445044
-
New triazole derivatives as antifungal agents: Synthesis via click reaction, in vitro evaluation and molecular docking studies
-
Zou, Y.; Zhao, Q.; Liao, J.; Hua, H.; Yu, S.; Chai, X.; Xu, M.; Wua, Q. New triazole derivatives as antifungal agents: Synthesis via click reaction, in vitro evaluation and molecular docking studies. Bioorg. Med. Chem. Lett. 2012, 22, 2959-2962.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 2959-2962
-
-
Zou, Y.1
Zhao, Q.2
Liao, J.3
Hua, H.4
Yu, S.5
Chai, X.6
Xu, M.7
Wua, Q.8
-
8
-
-
0035663918
-
Synthesis and antimicrobial activity of some 1,2,4-triazole-3- mercaptoacetic acid derivatives
-
Ulusoy, N.; Gursoy, A.; Otuk, G. Synthesis and antimicrobial activity of some 1,2,4-triazole-3- mercaptoacetic acid derivatives. Farmaco 2001, 56, 947-952.
-
(2001)
Farmaco
, vol.56
, pp. 947-952
-
-
Ulusoy, N.1
Gursoy, A.2
Otuk, G.3
-
9
-
-
33644644217
-
Synthesis and biological activities of new 1,2,4-triazol-3-one derivatives
-
Demirbas, N.; Demirbas, A.; Karaoglu, S.A. Synthesis and biological activities of new 1,2,4-triazol-3-one derivatives. Bioorg. Khim. 2005, 31, 430-440.
-
(2005)
Bioorg. Khim.
, vol.31
, pp. 430-440
-
-
Demirbas, N.1
Demirbas, A.2
Karaoglu, S.A.3
-
10
-
-
56949104357
-
Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of co(ii), ni(ii) and cu(ii) complexes with 1,2,4-triazole schiff bases
-
Bagihalli, G.B.; Avaji, P.G.; Patil, S.A.; Badami, P.S. Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases. Eur. J. Med. Chem. 2008, 43, 2639-2649.
-
(2008)
Eur. J. Med. Chem.
, vol.43
, pp. 2639-2649
-
-
Bagihalli, G.B.1
Avaji, P.G.2
Patil, S.A.3
Badami, P.S.4
-
11
-
-
33749238697
-
Synthesis and biological activity of schiff and mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety
-
Karthikeyan, M.S.; Prasad, D.J.; Poojary, B.; Bhat, K.S.; Holla, B.S.; Kumari, N.S. Synthesis and biological activity of Schiff and Mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety. Bioorg. Med. Chem. 2006, 14, 7482-7489.
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 7482-7489
-
-
Karthikeyan, M.S.1
Prasad, D.J.2
Poojary, B.3
Bhat, K.S.4
Holla, B.S.5
Kumari, N.S.6
-
12
-
-
0037294865
-
Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives
-
Dabak, K.; Sezer, O.; Akar, A.; Anac, O. Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives. Eur. J. Med. Chem. 2003, 38, 215-218.
-
(2003)
Eur. J. Med. Chem.
, vol.38
, pp. 215-218
-
-
Dabak, K.1
Sezer, O.2
Akar, A.3
Anac, O.4
-
13
-
-
81255169300
-
Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazolesas inhibitors of mycobacterium tuberculosis
-
Shanmugavelan, P.; Nagarajan, S.; Sathishkumar, M.; Ponnuswamy, A.; Yogeeswari, P.; Sriram, D. Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazolesas inhibitors of Mycobacterium tuberculosis. Bioorg. Med. Chem. Lett. 2011, 21, 7273-7276.
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 7273-7276
-
-
Shanmugavelan, P.1
Nagarajan, S.2
Sathishkumar, M.3
Ponnuswamy, A.4
Yogeeswari, P.5
Sriram, D.6
-
14
-
-
0347131149
-
In vitro study of some medicinally important mannich bases derived from antitubercular agent
-
Joshi, S.; Khosla, N.; Tiwari, P. In vitro study of some medicinally important Mannich bases derived from antitubercular agent. Bioorg. Med. Chem. 2004, 12, 571-576.
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 571-576
-
-
Joshi, S.1
Khosla, N.2
Tiwari, P.3
-
15
-
-
84859429130
-
Aglycone-focused randomization of 2-difluoromethylphenyltype sialoside suicide substrates for neuraminidases
-
Kai, H.; Hinou, H.; Nishimura, S.-I. Aglycone-focused randomization of 2-difluoromethylphenyltype sialoside suicide substrates for neuraminidases. Bioorg. Med. Chem. 2012, 20, 2739-2746.
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 2739-2746
-
-
Kai, H.1
Hinou, H.2
Nishimura, S.-I.3
-
16
-
-
0043158805
-
Synthesis, characterization and anticancer activity studies on some mannich bases derived from 1,2,4-triazoles
-
Holla, B.S.; Veerendra, B.; Shivananda, M.K.; Poojary, B. Synthesis, characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles. Eur. J. Med. Chem. 2003, 38, 759-767.
-
(2003)
Eur. J. Med. Chem.
, vol.38
, pp. 759-767
-
-
Holla, B.S.1
Veerendra, B.2
Shivananda, M.K.3
Poojary, B.4
-
17
-
-
84856213045
-
Inhibition of dengue virus and west nile virus proteases by click chemistryderived benz[d]isothiazol-3(2h)-one derivatives
-
Tiew, K.-C.; Dou, D.; Teramoto, T.; Lai, H.; Alliston, K.R.; Lushington, G.H.; Padmanabhan, R.; Groutas, W.C. Inhibition of Dengue virus and West Nile virus proteases by click chemistryderived benz[d]isothiazol-3(2H)-one derivatives. Bioorg. Med. Chem. 2012, 20, 1213-1221.
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 1213-1221
-
-
Tiew, K.-C.1
Dou, D.2
Teramoto, T.3
Lai, H.4
Alliston, K.R.5
Lushington, G.H.6
Padmanabhan, R.7
Groutas, W.C.8
-
18
-
-
0033617496
-
Synthesis and analgesic activity of some triazoles and triazolo-thiadiazines
-
Turan-Zitouni, G.; Kaplancikli, Z.A.; Erol, K.; Kilic, F.S. Synthesis and analgesic activity of some triazoles and triazolo-thiadiazines. Farmaco 1999, 54, 218-223.
-
(1999)
Farmaco
, vol.54
, pp. 218-223
-
-
Turan-Zitouni, G.1
Kaplancikli, Z.A.2
Erol, K.3
Kilic, F.S.4
-
19
-
-
84862777493
-
Design synthesis and biological evaluation of novel 2-methylpyrimidine-4- ylamine derivatives as inhibitors of escherichia coli pyruvate dehydrogenase complex e1
-
He, J.; Feng, L.; Li, J.; Tao, R.; Wang, F.; Liao, X.; Sun, Q.; Long, Q.; Ren, Y.; Wan, J.; He, H. Design, synthesis and biological evaluation of novel 2-methylpyrimidine-4-ylamine derivatives as inhibitors of Escherichia coli pyruvate dehydrogenase complex E1. Bioorg. Med. Chem 2012, 20, 1665-1670.
-
(2012)
Bioorg. Med. Chem
, vol.20
, pp. 1665-1670
-
-
He, J.1
Feng, L.2
Li, J.3
Tao, R.4
Wang, F.5
Liao, X.6
Sun, Q.7
Long, Q.8
Ren, Y.9
Wan, J.10
He, H.11
-
20
-
-
84856681904
-
Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold
-
Oh, K.; Yamada, K.; Asami, T.; Yoshizawa, Y. Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold. Bioorg. Med. Chem. Lett. 2012, 22, 1625-1628.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 1625-1628
-
-
Oh, K.1
Yamada, K.2
Asami, T.3
Yoshizawa, Y.4
-
21
-
-
15244344612
-
Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe
-
Malolanarasimhan, K.; Lai, C.C.; Kelley, J.A.; Iaccarino, L.; Reynolds, D.; Young, H.A.; Marquez, V.E. Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe. Bioorg. Med. Chem. 2005, 13, 2717-2722.
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 2717-2722
-
-
Malolanarasimhan, K.1
Lai, C.C.2
Kelley, J.A.3
Iaccarino, L.4
Reynolds, D.5
Young, H.A.6
Marquez, V.E.7
-
22
-
-
33744966628
-
A new solvent system for efficient synthesis of 1,2,3-triazoles
-
Lee, B.Y.; Park, S.R.; Jeon, H.B.; Kim, K.S. A new solvent system for efficient synthesis of 1,2,3-triazoles. Tetrahedron Lett. 2006, 47, 5105-5109.
-
(2006)
Tetrahedron Lett.
, vol.47
, pp. 5105-5109
-
-
Lee, B.Y.1
Park, S.R.2
Jeon, H.B.3
Kim, K.S.4
-
23
-
-
34948856398
-
Synthesis of glycosyl-triazole linked 1,2,4-oxadiazoles
-
dos Anjos, J.V.; Sinou, D.; de Melo, S.J.; Srivastava, R.M. Synthesis of glycosyl-triazole linked 1,2,4-oxadiazoles. Carbohydr. Res. 2007, 342, 2440-2449.
-
(2007)
Carbohydr. Res.
, vol.342
, pp. 2440-2449
-
-
Dos Anjos, J.V.1
Sinou, D.2
De Melo, S.J.3
Srivastava, R.M.4
-
24
-
-
11844255741
-
Copper(i)-catalyzed synthesis of azoles. Dft study predicts unprecedented reactivity and intermediates
-
Himo, F.; Lovell, T.; Hilgraf, H.; Rostovtsev, V.V.; Noodleman, L.; Sharpless, K.B.; Fokin, V.V. Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates. J. Am. Chem. Soc. 2005, 127, 210-216.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 210-216
-
-
Himo, F.1
Lovell, T.2
Hilgraf, H.3
Rostovtsev, V.V.4
Noodleman, L.5
Sharpless, K.B.6
Fokin, V.V.7
-
25
-
-
67650462258
-
Synthesis and cytotoxic profile of glycosyl triazole linked to 1,2,4-oxadiazole moiety at c-5 through a straight-chain carbon and oxygen atoms
-
dos Anjos, J.V.; Neves Filho, R.A.W.; Nascimento, S.C.; Srivastava, R.M.; Melo, S.J.; Sinou, D. Synthesis and cytotoxic profile of glycosyl triazole linked to 1,2,4-oxadiazole moiety at C-5 through a straight-chain carbon and oxygen atoms. Eur. J. Med. Chem. 2009, 44, 3571-3576.
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 3571-3576
-
-
Dos Anjos, J.V.1
Neves Filho, R.A.W.2
Nascimento, S.C.3
Srivastava, R.M.4
Melo, S.J.5
Sinou, D.6
-
26
-
-
70349214806
-
Discovery of highly potent novel antifungal azoles by structure-based rational design
-
Wang, W.; Sheng, C.; Che, X.; Ji, H.; Cao, Y.; Miao, Z.; Yao, J.; Zhang, W. Discovery of highly potent novel antifungal azoles by structure-based rational design. Bioorg. Med. Chem. Lett. 2009, 19, 5965-5969.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 5965-5969
-
-
Wang, W.1
Sheng, C.2
Che, X.3
Ji, H.4
Cao, Y.5
Miao, Z.6
Yao, J.7
Zhang, W.8
-
27
-
-
78649317458
-
Novel conformationally restricted triazole derivatives with potent antifungal activity
-
Wang, W.; Wang, S.; Liu, Y.; Dong, G.; Cao, Y.; Miao, Z.; Yao, J.; Zhang, W.; Sheng, C. Novel conformationally restricted triazole derivatives with potent antifungal activity. Eur. J. Med. Chem. 2010, 45, 6020-6026.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 6020-6026
-
-
Wang, W.1
Wang, S.2
Liu, Y.3
Dong, G.4
Cao, Y.5
Miao, Z.6
Yao, J.7
Zhang, W.8
Sheng, C.9
-
28
-
-
0021048099
-
A new approach to practical acute toxicity testing
-
Lorke, D. A new approach to practical acute toxicity testing. Arch. Toxicol. 1983, 54, 275-287.
-
(1983)
Arch. Toxicol.
, vol.54
, pp. 275-287
-
-
Lorke, D.1
-
29
-
-
0005868279
-
A method for maintaining phytomonas sepedomica for long periods without transfer
-
Sherf, A.F. A method for maintaining Phytomonas sepedomica for long periods without transfer. Phytopathology 1943, 31, 30-32.
-
(1943)
Phytopathology
, vol.31
, pp. 30-32
-
-
Sherf, A.F.1
-
30
-
-
0003503732
-
-
2nd ed.; Centraalbureau voor Schimmelcultures: Utrecht, The Netherlands and Universitat Rovira i Virgili: Reus, Spain
-
de Hoog, G.S.; Guarro, J.; Gene, J.; Figueras, M.J. Atlas of Clinical Fungi, 2nd ed.; Centraalbureau voor Schimmelcultures: Utrecht, The Netherlands and Universitat Rovira i Virgili: Reus, Spain, 2000; p. 1124.
-
(2000)
Atlas of Clinical Fungi
, pp. 1124
-
-
De Hoog, G.S.1
Guarro, J.2
Gene, J.3
Figueras, M.J.4
-
31
-
-
78649474716
-
-
Clinical Laboratory Standards Institute (CLSI). Approved standard-third edition M27-A3; CLSI: Wayne, PA, USA
-
Clinical Laboratory Standards Institute (CLSI). Reference Method for Broth Dilution Testing of Yeasts; Approved standard-third edition M27-A3; CLSI: Wayne, PA, USA, 2008.
-
(2008)
Reference Method for Broth Dilution Testing of Yeasts
-
-
-
32
-
-
0002125325
-
Pharmacological approaches to natural products screening and evaluation
-
Wagner, H., Wolf, P., Eds; Springer-Verlag: Berlin, Germany
-
Malone, M.H. Pharmacological Approaches to Natural Products Screening and Evaluation. In New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity; Wagner, H., Wolf, P., Eds; Springer-Verlag: Berlin, Germany, 1977; pp. 23-53.
-
(1977)
New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity
, pp. 23-53
-
-
Malone, M.H.1
-
33
-
-
84861500920
-
-
Organisation for Economic Co-operation and Development (OECD). OECD Guideline for Testing of Chemicals: Acute Oral Toxicity-Up-and-Down Procedure; n 425; OECD Publishing: Paris, France
-
Organisation for Economic Co-operation and Development (OECD). OECD Guideline for Testing of Chemicals: Acute Oral Toxicity-Up-and-Down Procedure; n 425; OECD Publishing: Paris, France, 2001.
-
-
-
|