Development of heptylmannoside-based glycoconjugate antiadhesive compounds against adherent-invasive escherichia coli bacteria associated with crohn’s disease

mBio

Volumn 6, Issue 6, 2015, Pages

  Sivignon, Adeline ^a,b   Yan, Xibo ^c,d,e   Dorta, Dimitri Alvarez ^f   Bonnet, Richard ^a,b,g   Bouckaert, Julie ^h   Fleury, Etienne ^c,d,e   Bernard, Julien ^c,d,e   Gouin, Sébastien G ^f   Darfeuille Michaud, Arlette ^a,b   Barnich, Nicolas ^a,b  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b CEMAGREF   (France)

^c UNIVERSITÉ DE LYON   (France)

^d UNIVERSITÉ DE LYON   (France)

^e CNRS   (France)

^f Centre National de la Recherche Scientifique   (France)

^g UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^h UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; AMIDE; AMPICILLIN; ANTIINFLAMMATORY AGENT; BETA CYCLODEXTRIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; CIMETIDINE; ERYTHROMYCIN; GLYCOCONJUGATE; HEPTYLMANNOSIDE; ISOPROPYLAMIDE; MANNOSIDE; STREPTOMYCIN; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; BETA CYCLODEXTRIN DERIVATIVE; CELL ADHESION MOLECULE; FIMBRIA PROTEIN; FIMH PROTEIN, E COLI; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; GM5893 PREDICTED PROTEIN, MOUSE; LEUKOCYTE ANTIGEN;

ADHERENT INVASIVE ESCHERICHIA COLI; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIADHESIVE EFFECT; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM ADHERENCE; BACTERIUM PILUS; CELL SURFACE; CHEMICAL STRUCTURE; COLITIS; CONTROLLED STUDY; CROHN DISEASE; DRUG ACTIVITY; DRUG EFFECT; ENTERITIS; ESCHERICHIA COLI; HOST CELL; HUMAN; HUMAN CELL; ILEUM MUCOSA; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; MOUSE; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYMPTOM; ANIMAL; ANTAGONISTS AND INHIBITORS; BACTERIAL LOAD; CHEMISTRY; CYTOLOGY; DRUG DEVELOPMENT; DRUG EFFECTS; EPITHELIUM CELL; ESCHERICHIA COLI INFECTIONS; FECES; FIMBRIA; GENETICS; GROWTH, DEVELOPMENT AND AGING; INTESTINE; METABOLISM; MICROBIOLOGY; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; SYNTHESIS;

ADHESINS, ESCHERICHIA COLI; ADMINISTRATION, ORAL; ANIMALS; ANTIGENS, CD; BACTERIAL ADHESION; BACTERIAL LOAD; BETA-CYCLODEXTRINS; CELL ADHESION MOLECULES; CROHN DISEASE; DRUG DISCOVERY; EPITHELIAL CELLS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FECES; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; GLYCOCONJUGATES; GPI-LINKED PROTEINS; INTESTINAL MUCOSA; INTESTINES; MANNOSIDES; MICE;

EID: 84952815301     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01298-15     Document Type: Article

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