In vitro assessment of alkylglycosides as permeability enhancers

AAPS PharmSciTech

Volumn 2, Issue 3, 2001, Pages 7-

  Eley, John G ^a   Triumalashetty, Prasanth ^a  

^a AUBURN UNIVERSITY   (United States)

Author keywords

Alkylglycosides; Permeability enhancers; Tight junctions

Indexed keywords

ALIPHATIC HYDROCARBON; GLYCOSIDE; CARBOHYDRATE DERIVATIVE; CARBON; DECYLGLUCOSIDE; DECYLMALTOSIDE; DODECYLMALTOSIDE; DRUG; DYE; HEXYLGLUCOSIDE; HEXYLMALTOSIDE; NONYLGLUCOSIDE; NONYLMALTOSIDE; OCTYL GLUCOSIDE; OCTYLMALTOSIDE; PENETRATION ENHANCING AGENT; TRIDECYLMALTOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CELL MEMBRANE PERMEABILITY; DRUG EFFECT; HUMAN; TIGHT JUNCTION; TRANSPORT AT THE CELLULAR LEVEL; CELL MEMBRANE; CELL TRANSPORT; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; ELECTRIC RESISTANCE; HUMAN CELL; IN VITRO STUDY; LIGHT CHAIN; MEMBRANE FLUIDITY; MEMBRANE TRANSPORT; MONOLAYER CULTURE; SOLUBILIZATION;

BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE PERMEABILITY; GLYCOSIDES; HUMANS; HYDROCARBONS, ACYCLIC; TIGHT JUNCTIONS;

EID: 23144460688     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt020319     Document Type: Article

References (13)

1. Moses AC, Gordon GS, Carey MC, Flier JS. Insulin administered intranasally as an insulin-bile salt aerosol: effectiveness and reproducibility in normal and diabetic subjects. Diabetes. 1989:32;1040-1047.
2. Atchison JA, Grizzle WE, Pillion DJ. Colonic absorption of insulin: an in vitro and in vivo evaluation. J Pharmacol ExpTherap. 1989:248;567-572.
3. Chiou GCY, Chuang C, Chang MS. Reduction of blood glucose concentrations with insulin eye drops. Diabetes Care. 1988:11;750-751.
4. Saffron M, Kuwar C, Savariar C, Burham J, William F, Neckers D. A new approach to the oral administration of insulin and other peptide drugs. Science. 1986:233;1081-1084.
5. Dimitrijevic D, Shaw AJ, Florence AT. Effects of some non-ionic surfactants on transepithelial permeability in Caco-2 cells. J Pharm Pharmacol. 2000:52(2);157-162.
6. Swenson ES, Milisen WB, Curatolo W. Intestinal permeability enhancement: efficiency, acute local toxicity and reversibility. Pharm Res. 1994:11(8);1132-1142.
7. Gordon GS, Moses AC, Silver RD, Flier JS, Carey MG. Nasal absorption of insulin: enhancement by hydrophobic bile salts. Proc Natl Acad Sci U S A. 1985:82;7419-7423.
8. Pontiroli AE, Alberetto M, Pajetta E, Calderara A, Pozza G. Human insulin plus sodium glycocholate in a nasal spray formulation: improved bioavailability and effectiveness in normal subjects. Diabetes Metab. 1987:13;441-443.
9. Pillion DJ, Hosmer S, Meezan E. Dodecylmaltoside-mediated nasal and ocular absorption of lyspro-insulin: independence of surfactant action from multimer dissociation. Pharm Res. 1988:15(10);1637-1639.
10. Pillion DJ, Bartlett JD, Meezan E, Yang M, Crain RJ, Grizzle WE. Systemic absorption of insulin delivered topically to the eye. Invest Ophthalmol Vis Sci. 1991:32;3021-3027.
11. Murakami M, Kusanoi Y, Takada K, Muranishi S. Assessment of enhancing ability of medium-chain alkylsaccharides as new absorption enhancers in rat rectum. Int J Pharm. 1992:79;159-169.
12. Attwood D, Florence AT. Surfactant Systems: Their Chemistry, Pharmacy and Biology. London, UK: Chapman and Hall, 1983:88-90.
13. Claude P, Goodenough D. Fracture faces of zonulae occludens from "tight" and "leaky" epithelia. J Cell Biol. 1973:58;390-400.