The tyrosine gate as a potential entropic lever in the receptor-binding site of the bacterial adhesin FimH

Biochemistry

Volumn 51, Issue 24, 2012, Pages 4790-4799

  Wellens, Adinda ^a   Lahmann, Martina ^b   Touaibia, Mohamed ^c,d   Vaucher, Jonathan ^d   Oscarson, Stefan ^e   Roy, René ^d   Remaut, Han ^a   Bouckaert, Julie ^a,f  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b BANGOR UNIVERSITY   (United Kingdom)

^c UNIVERSITÉ DE MONCTON   (Canada)

^d UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

^f UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; AGLYCONS; ANOMERICS; BINDING ENTHALPIES; CAUSATIVE AGENTS; CHEMICAL EQUATIONS; ELECTROSTATIC PROPERTIES; ENTROPIC CHANGES; LIGAND-FREE; PHENYL GROUP; PROPARGYL; RECEPTOR BINDING; SIDE-CHAINS; THERMODYNAMIC PROFILES; URINARY TRACT INFECTIONS; UROPATHOGENIC ESCHERICHIA COLI; UROTHELIUM;

BINDING SITES; DYNAMICS; ENTHALPY; ESCHERICHIA COLI; HYDROPHOBICITY; LIGANDS; OXYGEN;

AMINO ACIDS;

ADHESIN; AGLYCONE; ALPHA METHYL MANNOSIDE; BACTERIAL PROTEIN; LECTIN; PHENYL GROUP; PROTEIN FIMH ADHESIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM ADHERENCE; BINDING KINETICS; BINDING SITE; CONJUGATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENTHALPY; ENTROPY; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; STATIC ELECTRICITY; THERMODYNAMICS; URINARY TRACT INFECTION; UROPATHOGENIC ESCHERICHIA COLI; UROTHELIUM;

ADHESINS, ESCHERICHIA COLI; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENTROPY; ESCHERICHIA COLI; FIMBRIAE PROTEINS; GLYCOSIDES; LECTINS; LIGANDS; MANNOSE; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; TYROSINE;

EID: 84862564470     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300251r     Document Type: Article

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