Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

PLoS Pathogens

Volumn 9, Issue 1, 2013, Pages

  Dreux, Nicolas ^a   Denizot, Jérémy ^a   Martinez Medina, Margarita ^a   Mellmann, Alexander ^b   Billig, Maria ^c   Kisiela, Dagmara ^c   Chattopadhyay, Sujay ^c   Sokurenko, Evgeni ^c   Neut, Christel ^d   Gower Rousseau, Corinne ^d   Colombel, Jean Frédéric ^d   Bonnet, Richard ^a,e   Darfeuille Michaud, Arlette ^a,e,f   Barnich, Nicolas ^a,f  

^a CRNH Auvergne   (France)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIV LILLE   (France)

^e UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^f Institut Universitaire de Technologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE RECEPTOR; CYTOKINE; FIMH PROTEIN; INTERLEUKIN 1BETA; MEMBRANE PROTEIN; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM PILUS; COLITIS; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; ELECTRON MICROSCOPY; ENTERITIS; ESCHERICHIA COLI; GENETIC POLYMORPHISM; GROWTH RATE; HISTOLOGY; HUMAN; IMMUNOBLOTTING; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MOUSE; MULTILOCUS SEQUENCE TYPING; NUCLEOTIDE SEQUENCE; PHYLOGENY; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; SCORING SYSTEM; TRANSMISSION ELECTRON MICROSCOPY; YEAST;

ADHESINS, ESCHERICHIA COLI; ANIMALS; ANTIGENS, CD; BACTERIAL ADHESION; CELL ADHESION MOLECULES; CELL LINE, TUMOR; COLITIS; CROHN DISEASE; ENTEROCYTES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FIMBRIAE PROTEINS; GENES, BACTERIAL; GPI-LINKED PROTEINS; HUMANS; ILEUM; INTESTINAL MUCOSA; MALE; MICE; MICE, TRANSGENIC; POINT MUTATION; VIRULENCE FACTORS;

EID: 84875063030     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003141     Document Type: Article

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