Extracellular histones induce tissue factor expression in vascular endothelial cells via TLR and activation of NF-κB and AP-1

Thrombosis Research

Volumn 137, Issue , 2016, Pages 211-218

  Yang, Xinyu ^a   Li, Lin ^a   Liu, Jin ^a   Lv, Ben ^a   Chen, Fangping ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Histones; Thrombosis; Tissue factor

Indexed keywords

HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUTRALIZING ANTIBODY; PROCOAGULANT; THROMBOPLASTIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1; TOLL LIKE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA HISTONE INTERACTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE ACTIVATION; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSIENT EXPRESSION; VASCULAR ENDOTHELIUM; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; EXTRACELLULAR FLUID; IMMUNOLOGY;

CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; EXTRACELLULAR FLUID; HISTONES; HUMANS; NF-KAPPA B; THROMBOPLASTIN; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTOR AP-1;

EID: 84952639732     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2015.10.012     Document Type: Article

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