The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Archives of Biochemistry and Biophysics

Volumn 591, Issue , 2016, Pages 98-110

  Aumsuwan, Pranapda ^a   Khan, Shabana I ^a   Khan, Ikhlas A ^a   Ali, Zulfiqar ^a   Avula, Bharathi ^a   Walker, Larry A ^a   Shariat Madar, Zia ^a   Helferich, William G ^b   Katzenellenbogen, Benita S ^c   Dasmahapatra, Asok K ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Dioscin; GATA3; Gene expression; Invasion migration; ZFPM2

Indexed keywords

ANTINEOPLASTIC AGENT; DIOSCIN; DIOXYGENASE; DNA METHYLTRANSFERASE 3A; GELATINASE B; MESSENGER RNA; PLANT EXTRACT; SAPONIN DERIVATIVE; TET1 PROTEIN; TET2 PROTEIN; TET3 PROTEIN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WILD YAM ROOT EXTRACT; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN M2; DIOSGENIN; PHYTOSTEROL; SAPONIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; CELL INVASION; CELL INVASION ASSAY; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DIOSCOREA VILLOSA; DRUG ISOLATION; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MCF 7 CELL LINE; MEDICINAL PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WOUND; YAM; ANALOGS AND DERIVATIVES; BREAST NEOPLASMS; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PATHOLOGY; PLANT ROOT; TREATMENT OUTCOME; TUMOR CELL LINE; TUMOR INVASION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DIOSCOREA; DIOSGENIN; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MCF-7 CELLS; NEOPLASM INVASIVENESS; PHYTOSTEROLS; PLANT EXTRACTS; PLANT ROOTS; SAPONINS; TREATMENT OUTCOME;

EID: 84952362019     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2015.12.001     Document Type: Article

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