Saikosaponin a inhibits influenza A virus replication and lung immunopathology

Oncotarget

Volumn 6, Issue 40, 2015, Pages 42541-42556

  Chen, Jianxin ^a   Duan, Mubing ^b   Zhao, Yaqin ^a,d   Ling, Fangfang ^a   Xiao, Kun ^b   Li, Qian ^b   Li, Bin ^b,c   Lu, Chunni ^b   Qi, Wenbao ^a   Zeng, Zhenling ^a   Liao, Ming ^a   Liu, Yahong ^a   Chen, Weisan ^b  

^a SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^b LA TROBE UNIVERSITY   (Australia)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d Xinjiang Institute of Chinese Materia Medica   (China)

Author keywords

Anti inflammatory agent; Immune response; Immunity; Immunology and Microbiology Section; Influenza A virus; PR8; Saikosaponin A; X 31

Indexed keywords

CASPASE 3; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RIBONUCLEOPROTEIN; SAIKOSAPONIN A; SAPONIN; SYNAPTOTAGMIN I; TRITERPENE; ANTIVIRUS AGENT; OLEANOLIC ACID; SAIKOSAPONIN;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA A; INFLUENZA A (H5N1); INFLUENZA A VIRUS; LETHALITY; LUNG ALVEOLUS EPITHELIUM; LUNG IMMUNOPATHOLOGY; LUNG LAVAGE; LUNG PARENCHYMA; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; NUCLEAR EXPORT SIGNAL; TISSUE INJURY; VIRUS REPLICATION; VIRUS STRAIN; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL LINE; DISEASE MODEL; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; IMMUNOBLOTTING; IMMUNOLOGY; INFLUENZA; LUNG; ORTHOMYXOVIRIDAE INFECTIONS; PATHOLOGY; RESPIRATORY TRACT INFECTIONS; VIROLOGY;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOBLOTTING; INFLUENZA A VIRUS; INFLUENZA, HUMAN; LUNG; MICE; MICE, INBRED C57BL; OLEANOLIC ACID; ORTHOMYXOVIRIDAE INFECTIONS; RESPIRATORY TRACT INFECTIONS; SAPONINS; VIRUS REPLICATION;

EID: 84952342478     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6448     Document Type: Article

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