The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance

Cellular Microbiology

Volumn 15, Issue 7, 2013, Pages 1198-1211

  Ehrhardt, Christina ^a   Rückle, Andrea ^a   Hrincius, Eike R ^a   Haasbach, Emanuel ^b   Anhlan, Darisuren ^a   Ahmann, Katharina ^a   Banning, Carina ^a   Reiling, Sarah J ^e   Kühn, Joachim ^c   Strobl, Stefan ^d   Vitt, Daniel ^d   Leban, Johann ^d   Planz, Oliver ^b   Ludwig, Stephan ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b Institute for Cell Biology   (Germany)

^c Institute of Medical Microbiology   (Germany)

^d 4SC AG   (Germany)

^e FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; ANTIVIRUS AGENT; BETA INTERFERON; CASPASE 8; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INITIATOR CASPASE; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTRUCTURAL PROTEIN 1; OSELTAMIVIR; PROTEIN INHIBITOR; SC 75741; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE STORM; DNA BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLUENZA A; INFLUENZA VIRUS; INFLUENZA VIRUS A; INFLUENZA VIRUS B; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; VIRUS REPLICATION; VIRUS RESISTANCE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; LUNG; MICE; NF-KAPPA B; ORTHOMYXOVIRIDAE INFECTIONS; VIRUS REPLICATION;

AVES; MUS; ORTHOMYXOVIRIDAE; SUIDAE;

EID: 84879238988     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/cmi.12108     Document Type: Article

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