Saikosaponin A mediates the inflammatory response by inhibiting the MAPK and NF-κB pathways in LPS-stimulated RAW 264.7 cells

Experimental and Therapeutic Medicine

Volumn 5, Issue 5, 2013, Pages 1345-1350

  Zhu, Jie ^a   Luo, Chengqun ^a   Wang, Ping ^b   He, Quanyong ^a   Zhou, Jianda ^a   Peng, Hao ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b HUNAN CANCER HOSPITAL   (China)

Author keywords

Inflammation; Inflammatory cytokine; Lipopolysaccharide; Mitogen activated protein kinase; Nuclear factor and kappa; B; Saikosaponin A

Indexed keywords

CYCLOOXYGENASE 2; CYTOTOXIC FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; SAIKOSAPONIN A; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; INFLAMMATION; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 84876536136     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2013.988     Document Type: Article

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