Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

Journal of Experimental Medicine

Volumn 212, Issue 11, 2015, Pages 1819-1832

  Viny, Aaron D ^a   Ott, Christopher J ^b,c   Spitzer, Barbara ^a   Rivas, Martin ^d   Meydan, Cem ^d   Papalexi, Efthymia ^a   Yelin, Dana ^a,e   Shank, Kaitlyn ^a   Reyes, Jaime ^b   Chiu, April ^a   Romin, Yevgeniy ^a   Boyko, Vitaly ^a   Thota, Swapna ^f   Maciejewski, Jaroslaw P ^f   Melnick, Ari ^d   Bradner, James E ^b,c   Levine, Ross L ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e RABIN MEDICAL CENTER   (Israel)

^f TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COHESIN; CRE RECOMBINASE; FLT3 LIGAND; FLT3 LIGAND INTERNAL TANDEM DUPLICATION; HEMOGLOBIN; MX1 ENZYME; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN; SMC3 PROTEIN; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 2; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTOME; UNCLASSIFIED DRUG; CD135 ANTIGEN; CELL CYCLE PROTEIN; CHROMATIN; CSPG6 PROTEIN, MOUSE; FLT3 PROTEIN, MOUSE; NONHISTONE PROTEIN; PROTEOCHONDROITIN SULFATE;

ACUTE LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ALLELE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW APLASIA; BONE MARROW TRANSPLANTATION; CHIMERA; CHROMATIN STRUCTURE; CHROMOSOME STRUCTURE; COLONY FORMING UNIT GM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENHANCER REGION; ERYTHROCYTE; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION; GENE LOCUS; HAPLOINSUFFICIENCY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LEUKOCYTE COUNT; LEUKOCYTOSIS; LOSS OF FUNCTION MUTATION; LOXP SITE; MEGAKARYOCYTE; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PANCYTOPENIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RNA SEQUENCE; SIGNAL TRANSDUCTION; SISTER CHROMATID; SPLENOMEGALY; STEM CELL SELF-RENEWAL; T LYMPHOCYTE; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TRANSPLANTATION; ANIMAL; CHEMISTRY; CHROMATIN; GENETICS; LEUKEMIA, MYELOID, ACUTE; PHYSIOLOGY;

ANIMALS; CELL CYCLE PROTEINS; CHONDROITIN SULFATE PROTEOGLYCANS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; FMS-LIKE TYROSINE KINASE 3; HAPLOINSUFFICIENCY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; LEUKEMIA, MYELOID, ACUTE; MICE; STAT5 TRANSCRIPTION FACTOR;

EID: 84952038314     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20151317     Document Type: Article

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