Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy

Neurobiology of Disease

Volumn 82, Issue , 2015, Pages 289-297

  Pearson, Jennifer N ^a   Rowley, Shane ^a   Liang, Li Ping ^b   White, Andrew M ^a   Day, Brian J ^c   Patel, Manisha ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c DEPARTMENT OF MEDICINE   (United States)

Author keywords

Epilepsy; Learning and memory; Mitochondrial dysfunction; Neuronal loss; Oxidative stress; Pilocarpine; Reactive oxygen species

Indexed keywords

3 NITROTYROSINE; AEOL 10150; GLUTATHIONE; GLUTATHIONE DISULFIDE; OXYGEN; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; TYROSINE; UNCLASSIFIED DRUG; ANTIOXIDANT; NOOTROPIC AGENT; PILOCARPINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LOSS; COGNITIVE DEFECT; COMORBIDITY; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG HALF LIFE; DRUG PENETRATION; EPILEPTIC STATE; EPILEPTOGENESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; LONG TERM MEMORY; MALE; MITOCHONDRIAL RESPIRATION; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PATHOGENESIS; PRIORITY JOURNAL; RAT; SHORT TERM MEMORY; TEMPORAL LOBE EPILEPSY; ANIMAL; CELL DEATH; COGNITION DISORDERS; DISEASE MODEL; DRUG EFFECTS; EPILEPSY, TEMPORAL LOBE; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; PSYCHOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT; STATUS EPILEPTICUS;

ANIMALS; ANTIOXIDANTS; CELL DEATH; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; EPILEPSY, TEMPORAL LOBE; HIPPOCAMPUS; MALE; MITOCHONDRIA; NEURONS; NOOTROPIC AGENTS; OXIDATIVE STRESS; PILOCARPINE; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; STATUS EPILEPTICUS;

EID: 84951954910     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.07.005     Document Type: Article

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