Mitochondrial respiration deficits driven by reactive oxygen species in experimental temporal lobe epilepsy

Neurobiology of Disease

Volumn 75, Issue , 2015, Pages 151-158

  Rowley, Shane ^a   Liang, Li Ping ^a   Fulton, Ruth ^a   Shimizu, Takahiko ^b   Day, Brian ^c   Patel, Manisha ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c DEPARTMENT OF MEDICINE   (United States)

Author keywords

Kainic acid; Mitochondrial dysfunction; Oxidative stress; Seizures; Temporal lobe epilepsy

Indexed keywords

ANTIOXIDANT; DIAZEPAM; MANGANESE SUPEROXIDE DISMUTASE; MANGANESE TETRAKIS(DI N ETHYLIMIDAZOLE)PORPHYRIN; METALLOPORPHYRIN; OXYGEN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; KAINIC ACID; SUPEROXIDE DISMUTASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPILEPTOGENESIS; FEMALE; FOREBRAIN; GLYCOLYSIS; HIPPOCAMPUS; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; RAT; STEADY STATE; TEMPORAL LOBE EPILEPSY; ACUTE DISEASE; ANIMAL; CELL RESPIRATION; CHRONIC DISEASE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACUTE DISEASE; ANIMALS; ANTIOXIDANTS; CELL RESPIRATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; EPILEPSY, TEMPORAL LOBE; FEMALE; GLYCOLYSIS; HIPPOCAMPUS; KAINIC ACID; MALE; MICE, KNOCKOUT; MITOCHONDRIA; OXYGEN; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84921856704     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.12.025     Document Type: Article

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