MAC inhibitors antagonize the pro-apoptotic effects of tBid and disassemble Bax / Bak oligomers

Journal of Bioenergetics and Biomembranes

Volumn 49, Issue 1, 2017, Pages 65-74

  Peixoto, Pablo M ^a,c   Teijido, Oscar ^d   Mirzalieva, Oygul ^a   Dejean, Laurent M ^b   Pavlov, Evgeny V ^c   Antonsson, Bruno ^e   Kinnally, Kathleen W ^c  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

^c NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e MERCK SERONO S A   (Switzerland)

Author keywords

Apoptosis; Bak; Bax; MAC inhibitors; MOMP; Patch clamp; tBid

Indexed keywords

APOPTOSIS INDUCING FACTOR; CARBAZOLE DERIVATIVE; CYTOCHROME C; CYTOPROTECTIVE AGENT; MITOCHONDRIAL APOPTOTIC CHANNEL INHIBITOR; PROTEIN BAK; PROTEIN BAX; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG; BAK1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; FLUORESCENCE MICROSCOPY; GEL FILTRATION; GEL FILTRATION CHROMATOGRAPHY; HELA CELL LINE; IC50; MITOCHONDRION; MOUSE; NONHUMAN; OUTER MEMBRANE; PATCH CLAMP TECHNIQUE; STEADY STATE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DRUG EFFECTS; METABOLISM; PROTEIN MULTIMERIZATION;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARBAZOLES; CELL LINE; CYTOCHROMES C; FIBROBLASTS; MICE; MITOCHONDRIA; PROTEIN MULTIMERIZATION;

EID: 84951861857     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-015-9635-7     Document Type: Article

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