메뉴 건너뛰기




Volumn 36, Issue 1, 2016, Pages 40-54

Ischemic brain injury in cerebral amyloid angiopathy

Author keywords

Amyloid angiopathy; brain imaging; dementia; focal ischemia; vascular cognitive impairment

Indexed keywords

CORTICOSTEROID; DONEPEZIL; GALANTAMINE;

EID: 84951570038     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2015.88     Document Type: Review
Times cited : (112)

References (160)
  • 1
    • 0021318905 scopus 로고
    • Cerebral amyloid angiopathy manifesting as recurrent intracerebral hemorrhage
    • Finelli PF, Kessimian N and Bernstein PW. Cerebral amyloid angiopathy manifesting as recurrent intracerebral hemorrhage. Arch Neurol 1984; 41: 330-333
    • (1984) Arch Neurol , vol.41 , pp. 330-333
    • Finelli, P.F.1    Kessimian, N.2    Bernstein, P.W.3
  • 2
    • 7644219821 scopus 로고    scopus 로고
    • Amyloid angiopathy-related vascular cognitive impairment
    • Greenberg SM, Gurol ME, Rosand J and Smith EE. Amyloid angiopathy-related vascular cognitive impairment. Stroke 2004; 35: 2616-2619
    • (2004) Stroke , vol.35 , pp. 2616-2619
    • Greenberg, S.M.1    Gurol, M.E.2    Rosand, J.3    Smith, E.E.4
  • 3
    • 0036047520 scopus 로고    scopus 로고
    • Vascular-ischemic dementia: An update
    • Jellinger KA. Vascular-ischemic dementia: an update. J Neural Transm Suppl 2002; 62: 1-23
    • (2002) J Neural Transm Suppl , vol.62 , pp. 1-23
    • Jellinger, K.A.1
  • 4
    • 0009566277 scopus 로고    scopus 로고
    • Medical Research Council Cognitive Function and Aging Study. Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
    • Neuropathology Group
    • Neuropathology Group. Medical Research Council Cognitive Function and Aging Study. Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Lancet 2001; 357: 169-175
    • (2001) Lancet , vol.357 , pp. 169-175
  • 5
    • 84878381489 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy burden associated with leukoaraiosis: A positron emission tomography/magnetic resonance imaging study
    • Gurol ME, Viswanathan A, Gidicsin C, Hedden T, Martinez-Ramirez S, Dumas A, et al. Cerebral amyloid angiopathy burden associated with leukoaraiosis: a positron emission tomography/magnetic resonance imaging study. Ann Neurol 2013; 73: 529-536
    • (2013) Ann Neurol , vol.73 , pp. 529-536
    • Gurol, M.E.1    Viswanathan, A.2    Gidicsin, C.3    Hedden, T.4    Martinez-Ramirez, S.5    Dumas, A.6
  • 6
    • 33746463940 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia
    • Haglund M, Passant U, Sjobeck M, Ghebremedhin E and Englund E. Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia. Int J Geriatr Psychiatry 2006; 21: 681-687
    • (2006) Int J Geriatr Psychiatry , vol.21 , pp. 681-687
    • Haglund, M.1    Passant, U.2    Sjobeck, M.3    Ghebremedhin, E.4    Englund, E.5
  • 7
    • 41149127354 scopus 로고    scopus 로고
    • Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging
    • Holland CM, Smith EE, Csapo I, Gurol ME, Brylka DA, Killiany RJ, et al. Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke 2008; 39: 1127-1133
    • (2008) Stroke , vol.39 , pp. 1127-1133
    • Holland, C.M.1    Smith, E.E.2    Csapo, I.3    Gurol, M.E.4    Brylka, D.A.5    Killiany, R.J.6
  • 8
    • 84880147437 scopus 로고    scopus 로고
    • The relationship between cerebral amyloid angiopathy and cortical microinfarcts in brain ageing and Alzheimer's disease
    • Kovari E, Herrmann FR, Hof PR and Bouras C. The relationship between cerebral amyloid angiopathy and cortical microinfarcts in brain ageing and Alzheimer's disease. Neuropathol Appl Neurobiol 2013; 39: 498-509
    • (2013) Neuropathol Appl Neurobiol , vol.39 , pp. 498-509
    • Kovari, E.1    Herrmann, F.R.2    Hof, P.R.3    Bouras, C.4
  • 9
    • 79955733075 scopus 로고    scopus 로고
    • The impact of cerebral amyloid angiopathy on the occurrence of cerebrovascular lesions in demented patients with Alzheimer features: A neuropathological study
    • De Reuck J, Deramecourt V, Cordonnier C, Leys D, Maurage CA and Pasquier F. The impact of cerebral amyloid angiopathy on the occurrence of cerebrovascular lesions in demented patients with Alzheimer features: a neuropathological study. Eur J Neurol 2011; 18: 913-918
    • (2011) Eur J Neurol , vol.18 , pp. 913-918
    • De Reuck, J.1    Deramecourt, V.2    Cordonnier, C.3    Leys, D.4    Maurage, C.A.5    Pasquier, F.6
  • 11
    • 0037062566 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy and cognitive function: The HAAS autopsy study
    • Pfeifer LA, White LR, Ross GW, Petrovitch H and Launer LJ. Cerebral amyloid angiopathy and cognitive function: the HAAS autopsy study. Neurology 2002; 58: 1629-1634
    • (2002) Neurology , vol.58 , pp. 1629-1634
    • Pfeifer, L.A.1    White, L.R.2    Ross, G.W.3    Petrovitch, H.4    Launer, L.J.5
  • 13
    • 0029973286 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: The CERAD experience, Part XV
    • Ellis RJ, Olichney JM, Thal LJ, Mirra SS, Morris JC, Beekly D, et al. Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV. Neurology 1996; 46: 1592-1596
    • (1996) Neurology , vol.46 , pp. 1592-1596
    • Ellis, R.J.1    Olichney, J.M.2    Thal, L.J.3    Mirra, S.S.4    Morris, J.C.5    Beekly, D.6
  • 15
    • 70349847734 scopus 로고    scopus 로고
    • Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances
    • Thal DR, Capetillo-Zarate E, Larionov S, Staufenbiel M, Zurbruegg S and Beckmann N. Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances. Neurobiol Aging 2009; 30: 1936-1948
    • (2009) Neurobiol Aging , vol.30 , pp. 1936-1948
    • Thal, D.R.1    Capetillo-Zarate, E.2    Larionov, S.3    Staufenbiel, M.4    Zurbruegg, S.5    Beckmann, N.6
  • 17
    • 0028180541 scopus 로고
    • Beta-amyloid formation by myocytes of leptomeningeal vessels
    • Wisniewski HM and Wegiel J. Beta-amyloid formation by myocytes of leptomeningeal vessels. Acta Neuropathol 1994; 87: 233-241
    • (1994) Acta Neuropathol , vol.87 , pp. 233-241
    • Wisniewski, H.M.1    Wegiel, J.2
  • 18
    • 0028983336 scopus 로고
    • Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells
    • Davis-Salinas J, Saporito-Irwin SM, Cotman CW, Van and Nostrand WE. Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. J Neurochem 1995; 65: 931-934
    • (1995) J Neurochem , vol.65 , pp. 931-934
    • Davis-Salinas, J.1    Saporito-Irwin, S.M.2    Cotman, C.W.3    Van Nostrand, W.E.4
  • 19
    • 4344648449 scopus 로고    scopus 로고
    • Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
    • Herzig MC, Winkler DT, Burgermeister P, Pfeifer M, Kohler E, Schmidt SD, et al. Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis. Nat Neurosci 2004; 7: 954-960
    • (2004) Nat Neurosci , vol.7 , pp. 954-960
    • Herzig, M.C.1    Winkler, D.T.2    Burgermeister, P.3    Pfeifer, M.4    Kohler, E.5    Schmidt, S.D.6
  • 20
    • 2442594971 scopus 로고    scopus 로고
    • Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/ Iowa mutant form of amyloid beta-protein precursor
    • Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, et al. Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/ Iowa mutant form of amyloid beta-protein precursor. J Biol Chem 2004; 279: 20296-20306
    • (2004) J Biol Chem , vol.279 , pp. 20296-20306
    • Davis, J.1    Xu, F.2    Deane, R.3    Romanov, G.4    Previti, M.L.5    Zeigler, K.6
  • 21
    • 57449090951 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2
    • Vidal R, Barbeito AG, Miravalle L and Ghetti B. Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2. Brain Pathol 2009; 19: 58-68
    • (2009) Brain Pathol , vol.19 , pp. 58-68
    • Vidal, R.1    Barbeito, A.G.2    Miravalle, L.3    Ghetti, B.4
  • 22
    • 33646560610 scopus 로고    scopus 로고
    • Mechanism of cerebral beta-amyloid angiopathy: Murine and cellular models
    • Herzig MC, Van Nostrand WE and Jucker M. Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models. Brain Pathol 2006; 16: 40-54
    • (2006) Brain Pathol , vol.16 , pp. 40-54
    • Herzig, M.C.1    Van Nostrand, W.E.2    Jucker, M.3
  • 23
    • 41149157623 scopus 로고    scopus 로고
    • Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease
    • Weller RO, Subash M, Preston SD, Mazanti I and Carare RO. Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease. Brain Pathol 2008; 18: 253-266
    • (2008) Brain Pathol , vol.18 , pp. 253-266
    • Weller, R.O.1    Subash, M.2    Preston, S.D.3    Mazanti, I.4    Carare, R.O.5
  • 24
    • 79954623282 scopus 로고    scopus 로고
    • Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy
    • Hawkes CA, Hartig W, Kacza J, Schliebs R, Weller RO, Nicoll JA, et al. Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy. Acta Neuropathol 2011; 121: 431-443
    • (2011) Acta Neuropathol , vol.121 , pp. 431-443
    • Hawkes, C.A.1    Hartig, W.2    Kacza, J.3    Schliebs, R.4    Weller, R.O.5    Nicoll, J.A.6
  • 25
    • 4043061467 scopus 로고    scopus 로고
    • LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms
    • Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, et al. LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms. Neuron 2004; 43: 333-344
    • (2004) Neuron , vol.43 , pp. 333-344
    • Deane, R.1    Wu, Z.2    Sagare, A.3    Davis, J.4    Du Yan, S.5    Hamm, K.6
  • 26
    • 0022630783 scopus 로고
    • Cerebral amyloid angiopathy: The vascular pathology and complications
    • Mandybur TI. Cerebral amyloid angiopathy: the vascular pathology and complications. J Neuropathol Exp Neurol 1986; 45: 79-90
    • (1986) J Neuropathol Exp Neurol , vol.45 , pp. 79-90
    • Mandybur, T.I.1
  • 27
    • 0037333646 scopus 로고    scopus 로고
    • The vascular lesions in vascular and mixed dementia: The weight of functional neuroanatomy
    • Zekry D, Duyckaerts C, Belmin J, Geoffre C, Herrmann F, Moulias R, et al. The vascular lesions in vascular and mixed dementia: the weight of functional neuroanatomy. Neurobiol Aging 2003; 24: 213-219
    • (2003) Neurobiol Aging , vol.24 , pp. 213-219
    • Zekry, D.1    Duyckaerts, C.2    Belmin, J.3    Geoffre, C.4    Herrmann, F.5    Moulias, R.6
  • 28
    • 0031887307 scopus 로고    scopus 로고
    • Secondary microvascular degeneration in amyloid angiopathy of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D)
    • Vinters HV, Natte R, Maat-Schieman ML, van Duinen SG, Hegeman-Kleinn I, Welling-Graafland C, et al. Secondary microvascular degeneration in amyloid angiopathy of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D). Acta Neuropathol 1998; 95: 235-244
    • (1998) Acta Neuropathol , vol.95 , pp. 235-244
    • Vinters, H.V.1    Natte, R.2    Maat-Schieman, M.L.3    Van Duinen, S.G.4    Hegeman-Kleinn, I.5    Welling-Graafland, C.6
  • 29
    • 84980052642 scopus 로고    scopus 로고
    • Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue
    • Love S, Chalmers K, Ince P, Esiri M, Attems J, Jellinger K, et al. Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue. Am J Neurodegener Dis 2014; 3: 19-32
    • (2014) Am J Neurodegener Dis , vol.3 , pp. 19-32
    • Love, S.1    Chalmers, K.2    Ince, P.3    Esiri, M.4    Attems, J.5    Jellinger, K.6
  • 30
    • 0021075136 scopus 로고
    • Cerebral amyloid angiopathy: Incidence and complications in the aging brain. II. The distribution of amyloid vascular changes
    • Vinters HV and Gilbert JJ. Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes. Stroke 1983; 14: 924-928
    • (1983) Stroke , vol.14 , pp. 924-928
    • Vinters, H.V.1    Gilbert, J.J.2
  • 31
    • 0344737582 scopus 로고    scopus 로고
    • Vascular pathology in Alzheimer disease: Correlation of cerebral amyloid angiopathy and arteriosclerosis/lipohyalinosis with cognitive decline
    • Thal DR, Ghebremedhin E, Orantes Mand Wiestler OD. Vascular pathology in Alzheimer disease: correlation of cerebral amyloid angiopathy and arteriosclerosis/lipohyalinosis with cognitive decline. J Neuropathol Exp Neurol 2003; 62: 1287-1301
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 1287-1301
    • Thal, D.R.1    Ghebremedhin, E.2    Orantes Mand Wiestler, O.D.3
  • 32
    • 70349243761 scopus 로고    scopus 로고
    • Descriptive analysis of the Boston criteria applied to a Dutch-type cerebral amyloid angiopathy population
    • van Rooden S, van der Grond J, van den Boom R, Haan J, Linn J, Greenberg SM, et al. Descriptive analysis of the Boston criteria applied to a Dutch-type cerebral amyloid angiopathy population. Stroke 2009; 40: 3022-3027
    • (2009) Stroke , vol.40 , pp. 3022-3027
    • Van Rooden, S.1    Van Der Grond, J.2    Van Den Boom, R.3    Haan, J.4    Linn, J.5    Greenberg, S.M.6
  • 33
    • 0035957075 scopus 로고    scopus 로고
    • Clinical diagnosis of cerebral amyloid angiopathy: Validation of the Boston criteria
    • Knudsen KA, Rosand J, Karluk D and Greenberg SM. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology 2001; 56: 537-539
    • (2001) Neurology , vol.56 , pp. 537-539
    • Knudsen, K.A.1    Rosand, J.2    Karluk, D.3    Greenberg, S.M.4
  • 35
    • 81355134976 scopus 로고    scopus 로고
    • Cerebral microbleeds: Histopathological correlation of neuroimaging
    • Shoamanesh A, Kwok CS and Benavente O. Cerebral microbleeds: histopathological correlation of neuroimaging. Cerebrovasc Dis 2011; 32: 528-534
    • (2011) Cerebrovasc Dis , vol.32 , pp. 528-534
    • Shoamanesh, A.1    Kwok, C.S.2    Benavente, O.3
  • 36
    • 77953024409 scopus 로고    scopus 로고
    • Correlation of hypointensities in susceptibility-weighted images to tissue histology in dementia patients with cerebral amyloid angiopathy: A postmortem MRI study
    • Schrag M, McAuley G, Pomakian J, Jiffry A, Tung S, Mueller C, et al. Correlation of hypointensities in susceptibility-weighted images to tissue histology in dementia patients with cerebral amyloid angiopathy: a postmortem MRI study. Acta Neuropathol 2010; 119: 291-302
    • (2010) Acta Neuropathol , vol.119 , pp. 291-302
    • Schrag, M.1    McAuley, G.2    Pomakian, J.3    Jiffry, A.4    Tung, S.5    Mueller, C.6
  • 38
    • 79551713201 scopus 로고    scopus 로고
    • Brain microbleeds and Alzheimer's disease: Innocent observation or key player
    • Cordonnier C and van der Flier WM. Brain microbleeds and Alzheimer's disease: innocent observation or key player? Brain 2011; 134: 335-344
    • (2011) Brain , vol.134 , pp. 335-344
    • Cordonnier, C.1    Van Der Flier, W.M.2
  • 39
    • 84855582308 scopus 로고    scopus 로고
    • Sporadic cerebral amyloid angiopathy revisited: Recent insights into pathophysiology and clinical spectrum
    • Charidimou A, Gang Q and Werring DJ. Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum. J Neurol Neurosurg Psychiatry 2012; 83: 124-137
    • (2012) J Neurol Neurosurg Psychiatry , vol.83 , pp. 124-137
    • Charidimou, A.1    Gang, Q.2    Werring, D.J.3
  • 40
    • 84880391350 scopus 로고    scopus 로고
    • Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
    • Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013; 12: 822-838
    • (2013) Lancet Neurol , vol.12 , pp. 822-838
    • Wardlaw, J.M.1    Smith, E.E.2    Biessels, G.J.3    Cordonnier, C.4    Fazekas, F.5    Frayne, R.6
  • 42
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010; 9: 689-701
    • (2010) Lancet Neurol , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 43
    • 78649507260 scopus 로고    scopus 로고
    • Blood-brain barrier and cerebral small vessel disease
    • Wardlaw JM. Blood-brain barrier and cerebral small vessel disease. J Neurol Sci 2010; 299: 66-71
    • (2010) J Neurol Sci , vol.299 , pp. 66-71
    • Wardlaw, J.M.1
  • 45
    • 0036355286 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy, white matter lesions and Alzheimer encephalopathy-A histopathological assessment
    • Haglund M and Englund E. Cerebral amyloid angiopathy, white matter lesions and Alzheimer encephalopathy-a histopathological assessment. Dement Geriatr Cogn Disord 2002; 14: 161-166
    • (2002) Dement Geriatr Cogn Disord , vol.14 , pp. 161-166
    • Haglund, M.1    Englund, E.2
  • 47
    • 84913582825 scopus 로고    scopus 로고
    • Are acute infarcts the cause of leukoaraiosis? Brain mapping for 16 consecutive weeks
    • Conklin J, Silver FL, Mikulis DJ and Mandell DM. Are acute infarcts the cause of leukoaraiosis? Brain mapping for 16 consecutive weeks. Ann Neurol 2014; 76: 899-904
    • (2014) Ann Neurol , vol.76 , pp. 899-904
    • Conklin, J.1    Silver, F.L.2    Mikulis, D.J.3    Mandell, D.M.4
  • 48
    • 0030064215 scopus 로고    scopus 로고
    • White matter lesions and cognitive deterioration in presymptomatic carriers of the amyloid precursor protein gene codon 693 mutation
    • Bornebroek M, Haan J, van Buchem MA, Lanser JB, de Vries-vd Weerd MA, Zoeteweij M, et al. White matter lesions and cognitive deterioration in presymptomatic carriers of the amyloid precursor protein gene codon 693 mutation. Arch Neurol 1996; 53: 43-48
    • (1996) Arch Neurol , vol.53 , pp. 43-48
    • Bornebroek, M.1    Haan, J.2    Van Buchem, M.A.3    Lanser, J.B.4    De Vries-Vd Weerd, M.A.5    Zoeteweij, M.6
  • 49
    • 76649142080 scopus 로고    scopus 로고
    • 11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage
    • Ly JV, Donnan GA, Villemagne VL, Zavala JA, Ma H, O'Keefe G, et al. 11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage. Neurology 2010; 74: 487-493
    • (2010) Neurology , vol.74 , pp. 487-493
    • Ly, J.V.1    Donnan, G.A.2    Villemagne, V.L.3    Zavala, J.A.4    Ma, H.5    O'Keefe, G.6
  • 51
    • 84867880031 scopus 로고    scopus 로고
    • Predicting sites of new hemorrhage with amyloid imaging in cerebral amyloid angiopathy
    • Gurol ME, Dierksen G, Betensky R, Gidicsin C, Halpin A, Becker A, et al. Predicting sites of new hemorrhage with amyloid imaging in cerebral amyloid angiopathy. Neurology 2012; 79: 320-326
    • (2012) Neurology , vol.79 , pp. 320-326
    • Gurol, M.E.1    Dierksen, G.2    Betensky, R.3    Gidicsin, C.4    Halpin, A.5    Becker, A.6
  • 53
    • 84862522302 scopus 로고    scopus 로고
    • Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging
    • Zhu YC, Chabriat H, Godin O, Dufouil C, Rosand J, Greenberg SM, et al. Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging. J Neurol 2012; 259: 530-536
    • (2012) J Neurol , vol.259 , pp. 530-536
    • Zhu, Y.C.1    Chabriat, H.2    Godin, O.3    Dufouil, C.4    Rosand, J.5    Greenberg, S.M.6
  • 55
    • 0029038881 scopus 로고
    • Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension
    • Olichney JM, Hansen LA, Hofstetter CR, Grundman M, Katzman R and Thal LJ. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension. Arch Neurol 1995; 52: 702-708
    • (1995) Arch Neurol , vol.52 , pp. 702-708
    • Olichney, J.M.1    Hansen, L.A.2    Hofstetter, C.R.3    Grundman, M.4    Katzman, R.5    Thal, L.J.6
  • 57
    • 84857922274 scopus 로고    scopus 로고
    • Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts
    • Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, et al. Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts. Acta Neuropathol 2012; 123: 381-394
    • (2012) Acta Neuropathol , vol.123 , pp. 381-394
    • Okamoto, Y.1    Yamamoto, T.2    Kalaria, R.N.3    Senzaki, H.4    Maki, T.5    Hase, Y.6
  • 59
    • 80051957747 scopus 로고    scopus 로고
    • Acute ischaemic brain lesions in intracerebral haemorrhage: Multicentre cross-sectional magnetic resonance imaging study
    • Gregoire SM, Charidimou A, Gadapa N, Dolan E, Antoun N, Peeters A, et al. Acute ischaemic brain lesions in intracerebral haemorrhage: multicentre cross-sectional magnetic resonance imaging study. Brain 2011; 134: 2376-2386
    • (2011) Brain , vol.134 , pp. 2376-2386
    • Gregoire, S.M.1    Charidimou, A.2    Gadapa, N.3    Dolan, E.4    Antoun, N.5    Peeters, A.6
  • 60
    • 65249142147 scopus 로고    scopus 로고
    • Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy
    • Kimberly WT, Gilson A, Rost NS, Rosand J, Viswanathan A, Smith EE, et al. Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy. Neurology 2009; 72: 1230-1235
    • (2009) Neurology , vol.72 , pp. 1230-1235
    • Kimberly, W.T.1    Gilson, A.2    Rost, N.S.3    Rosand, J.4    Viswanathan, A.5    Smith, E.E.6
  • 61
    • 84871302239 scopus 로고    scopus 로고
    • Characteristic distributions of intracerebral hemorrhage-associated diffusion-weighted lesions
    • Auriel E, Gurol ME, Ayres A, Dumas AP, Schwab KM, Vashkevich A, et al. Characteristic distributions of intracerebral hemorrhage-associated diffusion-weighted lesions. Neurology 2012; 79: 2335-2341
    • (2012) Neurology , vol.79 , pp. 2335-2341
    • Auriel, E.1    Gurol, M.E.2    Ayres, A.3    Dumas, A.P.4    Schwab, K.M.5    Vashkevich, A.6
  • 62
    • 84903940240 scopus 로고    scopus 로고
    • Microinfarct disruption of white matter structure: A longitudinal diffusion tensor analysis
    • Auriel E, Edlow BL, Reijmer YD, Fotiadis P, Ramirez-Martinez S, Ni J, et al. Microinfarct disruption of white matter structure: A longitudinal diffusion tensor analysis. Neurology 2014; 83: 182-188
    • (2014) Neurology , vol.83 , pp. 182-188
    • Auriel, E.1    Edlow, B.L.2    Reijmer, Y.D.3    Fotiadis, P.4    Ramirez-Martinez, S.5    Ni, J.6
  • 64
    • 36148972426 scopus 로고    scopus 로고
    • Pathological correlates of dementia in a longitudinal, population-based sample of aging
    • Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD, et al. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol 2007; 62: 406-413
    • (2007) Ann Neurol , vol.62 , pp. 406-413
    • Sonnen, J.A.1    Larson, E.B.2    Crane, P.K.3    Haneuse, S.4    Li, G.5    Schellenberg, G.D.6
  • 65
    • 83255181787 scopus 로고    scopus 로고
    • Microinfarcts brain atrophy, and cognitive function: The Honolulu Asia Aging Study Autopsy Study
    • Launer LJ, Hughes TM and White LR. Microinfarcts brain atrophy, and cognitive function: the Honolulu Asia Aging Study Autopsy Study. Ann Neurol 2011; 70: 774-780
    • (2011) Ann Neurol , vol.70 , pp. 774-780
    • Launer, L.J.1    Hughes, T.M.2    White, L.R.3
  • 66
    • 78650173768 scopus 로고    scopus 로고
    • Small vascular and Alzheimer diseaserelated pathologic determinants of dementia in the oldestold
    • Sinka L, Kovari E, Gold G, Hof PR, Herrmann FR, Bouras C, et al. Small vascular and Alzheimer diseaserelated pathologic determinants of dementia in the oldestold. J Neuropathol Exp Neurol 2010; 69: 1247-1255
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 1247-1255
    • Sinka, L.1    Kovari, E.2    Gold, G.3    Hof, P.R.4    Herrmann, F.R.5    Bouras, C.6
  • 69
    • 84920602939 scopus 로고    scopus 로고
    • 7T T2()-weighted magnetic resonance imaging reveals cortical phase differences between early-and late-onset Alzheimer's disease
    • van Rooden S, Doan NT, Versluis MJ, Goos JD, Webb AG, Oleksik AM, et al. 7T T2()-weighted magnetic resonance imaging reveals cortical phase differences between early-and late-onset Alzheimer's disease. Neurobiol Aging 2015; 36: 20-26
    • (2015) Neurobiol Aging , vol.36 , pp. 20-26
    • Van Rooden, S.1    Doan, N.T.2    Versluis, M.J.3    Goos, J.D.4    Webb, A.G.5    Oleksik, A.M.6
  • 70
    • 84928227776 scopus 로고    scopus 로고
    • In vivo high-resolution 7 Tesla MRI shows early and diffuse cortical alterations in CADASIL
    • De Guio F, Reyes S, Vignaud A, Duering M, Ropele S, Duchesnay E, et al. In vivo high-resolution 7 Tesla MRI shows early and diffuse cortical alterations in CADASIL. PLoS One 2014; 9: e106311
    • (2014) PLoS One , vol.9 , pp. e106311
    • De Guio, F.1    Reyes, S.2    Vignaud, A.3    Duering, M.4    Ropele, S.5    Duchesnay, E.6
  • 71
    • 78650196681 scopus 로고    scopus 로고
    • Hippocampal degeneration is associated with temporal and limbic gray matter/white matter tissue contrast in Alzheimer's disease
    • Salat DH, Chen JJ, van der Kouwe AJ, Greve DN, Fischl B and Rosas HD. Hippocampal degeneration is associated with temporal and limbic gray matter/white matter tissue contrast in Alzheimer's disease. Neuroimage 2011; 54: 1795-1802
    • (2011) Neuroimage , vol.54 , pp. 1795-1802
    • Salat, D.H.1    Chen, J.J.2    Van Der Kouwe, A.J.3    Greve, D.N.4    Fischl, B.5    Rosas, H.D.6
  • 72
  • 76
    • 83055194303 scopus 로고    scopus 로고
    • Microstructural white matter abnormalities in type 2 diabetes mellitus: A diffusion tensor imaging study
    • Hsu JL, Chen YL, Leu JG, Jaw FS, Lee CH, Tsai YF, et al. Microstructural white matter abnormalities in type 2 diabetes mellitus: a diffusion tensor imaging study. Neuroimage 2012; 59: 1098-1105
    • (2012) Neuroimage , vol.59 , pp. 1098-1105
    • Hsu, J.L.1    Chen, Y.L.2    Leu, J.G.3    Jaw, F.S.4    Lee, C.H.5    Tsai, Y.F.6
  • 78
    • 84887259294 scopus 로고    scopus 로고
    • Multiple Microbleeds are Related to Cerebral Network Disruptions in Patients with Early Alzheimer's Disease
    • Heringa SM, Reijmer YD, Leemans A, Koek HL, Kappelle LJ and Biessels GJ. Multiple Microbleeds are Related to Cerebral Network Disruptions in Patients with Early Alzheimer's Disease. J Alzheimers Dis 2014; 38: 211-221
    • (2014) J Alzheimers Dis , vol.38 , pp. 211-221
    • Heringa, S.M.1    Reijmer, Y.D.2    Leemans, A.3    Koek, H.L.4    Kappelle, L.J.5    Biessels, G.J.6
  • 79
    • 33745932543 scopus 로고    scopus 로고
    • White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging
    • Salat DH, Smith EE, Tuch DS, Benner T, Pappu V, Schwab KM, et al. White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging. Stroke 2006; 37: 1759-1764
    • (2006) Stroke , vol.37 , pp. 1759-1764
    • Salat, D.H.1    Smith, E.E.2    Tuch, D.S.3    Benner, T.4    Pappu, V.5    Schwab, K.M.6
  • 80
  • 82
    • 0029665096 scopus 로고    scopus 로고
    • Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
    • Premkumar DR, Cohen DL, Hedera P, Friedland RP and Kalaria RN. Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am J Pathol 1996; 148: 2083-2095
    • (1996) Am J Pathol , vol.148 , pp. 2083-2095
    • Premkumar, D.R.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5
  • 83
    • 84930166765 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy increases susceptibility to infarction after focal cerebral ischemia in Tg2576 mice
    • Milner E, Zhou ML, Johnson AW, Vellimana AK, Greenberg JK, Holtzman DM, et al. Cerebral amyloid angiopathy increases susceptibility to infarction after focal cerebral ischemia in Tg2576 mice. Stroke 2014; 45: 3064-3069
    • (2014) Stroke , vol.45 , pp. 3064-3069
    • Milner, E.1    Zhou, M.L.2    Johnson, A.W.3    Vellimana, A.K.4    Greenberg, J.K.5    Holtzman, D.M.6
  • 84
    • 84856429045 scopus 로고    scopus 로고
    • Amyloid-beta contributes to bloodbrain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy
    • Hartz AM, Bauer B, Soldner EL, Wolf A, Boy S, Backhaus R, et al. Amyloid-beta contributes to bloodbrain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy. Stroke 2012; 43: 514-523
    • (2012) Stroke , vol.43 , pp. 514-523
    • Hartz, A.M.1    Bauer, B.2    Soldner, E.L.3    Wolf, A.4    Boy, S.5    Backhaus, R.6
  • 85
    • 34548225478 scopus 로고    scopus 로고
    • Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy
    • Shin HK, Jones PB, Garcia-Alloza M, Borrelli L, Greenberg SM, Bacskai BJ, et al. Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain 2007; 130: 2310-2319
    • (2007) Brain , vol.130 , pp. 2310-2319
    • Shin, H.K.1    Jones, P.B.2    Garcia-Alloza, M.3    Borrelli, L.4    Greenberg, S.M.5    Bacskai, B.J.6
  • 86
    • 0035090079 scopus 로고    scopus 로고
    • Analysis of cerebral amyloid angiopathy in a transgenic mouse model of Alzheimer disease using in vivo multiphoton microscopy
    • Kimchi EY, Kajdasz S, Bacskai BJ and Hyman BT. Analysis of cerebral amyloid angiopathy in a transgenic mouse model of Alzheimer disease using in vivo multiphoton microscopy. J Neuropathol Exp Neurol 2001; 60: 274-279
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 274-279
    • Kimchi, E.Y.1    Kajdasz, S.2    Bacskai, B.J.3    Hyman, B.T.4
  • 87
    • 58149373440 scopus 로고    scopus 로고
    • Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: Contribution of soluble and insoluble amyloid-beta peptide, partial restoration via gamma-secretase inhibition
    • Han BH, Zhou ML, Abousaleh F, Brendza RP, Dietrich HH, Koenigsknecht-Talboo J, et al. Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: contribution of soluble and insoluble amyloid-beta peptide, partial restoration via gamma-secretase inhibition. J Neurosci 2008; 28: 13542-13550
    • (2008) J Neurosci , vol.28 , pp. 13542-13550
    • Han, B.H.1    Zhou, M.L.2    Abousaleh, F.3    Brendza, R.P.4    Dietrich, H.H.5    Koenigsknecht-Talboo, J.6
  • 88
    • 58149237384 scopus 로고    scopus 로고
    • Impaired visual evoked flow velocity response in cerebral amyloid angiopathy
    • Smith EE, Vijayappa M, Lima F, Delgado P, Wendell L, Rosand J, et al. Impaired visual evoked flow velocity response in cerebral amyloid angiopathy. Neurology 2008; 71: 1424-1430
    • (2008) Neurology , vol.71 , pp. 1424-1430
    • Smith, E.E.1    Vijayappa, M.2    Lima, F.3    Delgado, P.4    Wendell, L.5    Rosand, J.6
  • 89
    • 84864447648 scopus 로고    scopus 로고
    • Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy
    • Dumas A, Dierksen GA, Gurol ME, Halpin A, Martinez-Ramirez S, Schwab K, et al. Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy. Ann Neurol 2012; 72: 76-81
    • (2012) Ann Neurol , vol.72 , pp. 76-81
    • Dumas, A.1    Dierksen, G.A.2    Gurol, M.E.3    Halpin, A.4    Martinez-Ramirez, S.5    Schwab, K.6
  • 90
    • 84888222982 scopus 로고    scopus 로고
    • Neurovascular decoupling is associated with severity of cerebral amyloid angiopathy
    • Peca S, McCreary CR, Donaldson E, Kumarpillai G, Shobha N, Sanchez K, et al. Neurovascular decoupling is associated with severity of cerebral amyloid angiopathy. Neurology 2013; 81: 1659-1665
    • (2013) Neurology , vol.81 , pp. 1659-1665
    • Peca, S.1    McCreary, C.R.2    Donaldson, E.3    Kumarpillai, G.4    Shobha, N.5    Sanchez, K.6
  • 92
    • 84923327428 scopus 로고    scopus 로고
    • White matter changes in dementia: Role of impaired drainage of interstitial fluid
    • Weller RO, Hawkes CA, Kalaria RN, Werring DJ and Carare RO. White matter changes in dementia: role of impaired drainage of interstitial fluid. Brain Pathol 2015; 25: 63-78
    • (2015) Brain Pathol , vol.25 , pp. 63-78
    • Weller, R.O.1    Hawkes, C.A.2    Kalaria, R.N.3    Werring, D.J.4    Carare, R.O.5
  • 93
    • 84892148180 scopus 로고    scopus 로고
    • White matter perivascular spaces: An MRI marker in pathology-proven cerebral amyloid angiopathy
    • Charidimou A, Jaunmuktane Z, Baron JC, Burnell M, Varlet P, Peeters A, et al. White matter perivascular spaces: an MRI marker in pathology-proven cerebral amyloid angiopathy? Neurology 2014; 82: 57-62
    • (2014) Neurology , vol.82 , pp. 57-62
    • Charidimou, A.1    Jaunmuktane, Z.2    Baron, J.C.3    Burnell, M.4    Varlet, P.5    Peeters, A.6
  • 95
    • 84925283413 scopus 로고    scopus 로고
    • Topography and associations of perivascular spaces in healthy adults: The Kashima scan study
    • Yakushiji Y, Charidimou A, Hara M, Noguchi T, Nishihara M, Eriguchi M, et al. Topography and associations of perivascular spaces in healthy adults: the Kashima scan study. Neurology 2014; 83: 2116-2123
    • (2014) Neurology , vol.83 , pp. 2116-2123
    • Yakushiji, Y.1    Charidimou, A.2    Hara, M.3    Noguchi, T.4    Nishihara, M.5    Eriguchi, M.6
  • 96
    • 73449128277 scopus 로고    scopus 로고
    • Neuroimaging demonstration of evolving small vessel ischemic injury in cerebral amyloid angiopathy
    • Menon RS and Kidwell CS. Neuroimaging demonstration of evolving small vessel ischemic injury in cerebral amyloid angiopathy. Stroke 2009; 40: e675-e677
    • (2009) Stroke , vol.40 , pp. e675-e677
    • Menon, R.S.1    Kidwell, C.S.2
  • 97
    • 80054788494 scopus 로고    scopus 로고
    • Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration
    • Rosidi NL, Zhou J, Pattanaik S, Wang P, Jin W, Brophy M, et al. Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration. PLoS ONE 2011; 6: e26612
    • (2011) PLoS ONE , vol.6 , pp. e26612
    • Rosidi, N.L.1    Zhou, J.2    Pattanaik, S.3    Wang, P.4    Jin, W.5    Brophy, M.6
  • 98
    • 0035203856 scopus 로고    scopus 로고
    • Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles
    • Natte R, Maat-Schieman ML, Haan J, Bornebroek M, Roos RA and van Duinen SG. Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles. Ann Neurol 2001; 50: 765-772
    • (2001) Ann Neurol , vol.50 , pp. 765-772
    • Natte, R.1    Maat-Schieman, M.L.2    Haan, J.3    Bornebroek, M.4    Roos, R.A.5    Van Duinen, S.G.6
  • 99
    • 0032891220 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy in Alzheimer disease is associated with apolipoprotein E4 and cortical neuron loss
    • Zarow C, Zaias B, Lyness SA and Chui H. Cerebral amyloid angiopathy in Alzheimer disease is associated with apolipoprotein E4 and cortical neuron loss. Alzheimer Dis Assoc Disord 1999; 13: 1-8
    • (1999) Alzheimer Dis Assoc Disord , vol.13 , pp. 1-8
    • Zarow, C.1    Zaias, B.2    Lyness, S.A.3    Chui, H.4
  • 100
    • 78149433845 scopus 로고    scopus 로고
    • Myelination and support of axonal integrity by glia
    • Nave KA. Myelination and support of axonal integrity by glia. Nature 2010; 468: 244-252
    • (2010) Nature , vol.468 , pp. 244-252
    • Nave, K.A.1
  • 101
    • 84865609374 scopus 로고    scopus 로고
    • High prevalence of cerebral microbleeds at 7Tesla MRI in patients with early Alzheimer's disease
    • Brundel M, Heringa SM, de BJ, Koek HL, Zwanenburg JJ, Jaap KL, et al. High prevalence of cerebral microbleeds at 7Tesla MRI in patients with early Alzheimer's disease. J Alzheimers Dis 2012; 31: 259-263
    • (2012) J Alzheimers Dis , vol.31 , pp. 259-263
    • Brundel, M.1    Heringa, S.M.2    De, B.J.3    Koek, H.L.4    Zwanenburg, J.J.5    Jaap, K.L.6
  • 102
    • 45149113307 scopus 로고    scopus 로고
    • Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study
    • Pettersen JA, Sathiyamoorthy G, Gao FQ, Szilagyi G, Nadkarni NK, St, George-Hyslop P, et al. Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol 2008; 65: 790-795
    • (2008) Arch Neurol , vol.65 , pp. 790-795
    • Pettersen, J.A.1    Sathiyamoorthy, G.2    Gao, F.Q.3    Szilagyi, G.4    Nadkarni, N.K.5    St George-Hyslop, P.6
  • 103
    • 65249160528 scopus 로고    scopus 로고
    • Progression of mild cognitive impairment to dementia: Contribution of cerebrovascular disease compared with medial temporal lobe atrophy
    • Staekenborg SS, Koedam EL, Henneman WJ, Stokman P, Barkhof F, Scheltens P, et al. Progression of mild cognitive impairment to dementia: contribution of cerebrovascular disease compared with medial temporal lobe atrophy. Stroke 2009; 40: 1269-1274
    • (2009) Stroke , vol.40 , pp. 1269-1274
    • Staekenborg, S.S.1    Koedam, E.L.2    Henneman, W.J.3    Stokman, P.4    Barkhof, F.5    Scheltens, P.6
  • 106
    • 84863304075 scopus 로고    scopus 로고
    • Distributional impact of brain microbleeds on global cognitive function in adults without neurological disorder
    • Yakushiji Y, Noguchi T, Hara M, Nishihara M, Eriguchi M, Nanri Y, et al. Distributional impact of brain microbleeds on global cognitive function in adults without neurological disorder. Stroke 2012; 43: 1800-1805
    • (2012) Stroke , vol.43 , pp. 1800-1805
    • Yakushiji, Y.1    Noguchi, T.2    Hara, M.3    Nishihara, M.4    Eriguchi, M.5    Nanri, Y.6
  • 107
    • 84907548976 scopus 로고    scopus 로고
    • Cerebral microvascular lesions on high-resolution 7-Tesla MRI in patients with type 2 diabetes
    • Brundel M, Reijmer YD, van Veluw SJ, Kuijf HJ, Luijten PR, Kappelle LJ, et al. Cerebral microvascular lesions on high-resolution 7-Tesla MRI in patients with type 2 diabetes. Diabetes 2014; 63: 3523-3529
    • (2014) Diabetes , vol.63 , pp. 3523-3529
    • Brundel, M.1    Reijmer, Y.D.2    Van Veluw, S.J.3    Kuijf, H.J.4    Luijten, P.R.5    Kappelle, L.J.6
  • 109
    • 78649658554 scopus 로고    scopus 로고
    • Cerebral microhemorrhage and iron deposition in mild cognitive impairment: Susceptibilityweighted MR imaging assessment
    • Haller S, Bartsch A, Nguyen D, Rodriguez C, Emch J, Gold G, et al. Cerebral microhemorrhage and iron deposition in mild cognitive impairment: susceptibilityweighted MR imaging assessment. Radiology 2010; 257: 764-773
    • (2010) Radiology , vol.257 , pp. 764-773
    • Haller, S.1    Bartsch, A.2    Nguyen, D.3    Rodriguez, C.4    Emch, J.5    Gold, G.6
  • 110
    • 70350548210 scopus 로고    scopus 로고
    • Patients with Alzheimer disease with multiple microbleeds: Relation with cerebrospinal fluid biomarkers and cognition
    • Goos JD, Kester MI, Barkhof F, Klein M, Blankenstein MA, Scheltens P, et al. Patients with Alzheimer disease with multiple microbleeds: relation with cerebrospinal fluid biomarkers and cognition. Stroke 2009; 40: 3455-3460
    • (2009) Stroke , vol.40 , pp. 3455-3460
    • Goos, J.D.1    Kester, M.I.2    Barkhof, F.3    Klein, M.4    Blankenstein, M.A.5    Scheltens, P.6
  • 111
    • 84858010697 scopus 로고    scopus 로고
    • Cerebral microbleeds are associated with worse cognitive function: The Rotterdam Scan Study
    • Poels MM, Ikram MA, van der Lugt A, Hofman A, Niessen WJ, Krestin GP, et al. Cerebral microbleeds are associated with worse cognitive function: the Rotterdam Scan Study. Neurology 2012; 78: 326-333
    • (2012) Neurology , vol.78 , pp. 326-333
    • Poels, M.M.1    Ikram, M.A.2    Van Der Lugt, A.3    Hofman, A.4    Niessen, W.J.5    Krestin, G.P.6
  • 112
    • 84872964449 scopus 로고    scopus 로고
    • Cerebral microbleeds and cognition in patients with symptomatic small vessel disease
    • Patel B, Lawrence AJ, Chung AW, Rich P, Mackinnon AD, Morris RG, et al. Cerebral microbleeds and cognition in patients with symptomatic small vessel disease. Stroke 2013; 44: 356-361
    • (2013) Stroke , vol.44 , pp. 356-361
    • Patel, B.1    Lawrence, A.J.2    Chung, A.W.3    Rich, P.4    Mackinnon, A.D.5    Morris, R.G.6
  • 113
    • 4944264340 scopus 로고    scopus 로고
    • Cognitive dysfunction in patients with cerebral microbleeds on T2-weighted gradientecho MRI
    • Werring DJ, Frazer DW, Coward LJ, Losseff NA, Watt H, Cipolotti L, et al. Cognitive dysfunction in patients with cerebral microbleeds on T2-weighted gradientecho MRI. Brain 2004; 127: 2265-2275
    • (2004) Brain , vol.127 , pp. 2265-2275
    • Werring, D.J.1    Frazer, D.W.2    Coward, L.J.3    Losseff, N.A.4    Watt, H.5    Cipolotti, L.6
  • 114
    • 84856221700 scopus 로고    scopus 로고
    • Frontal and temporal microbleeds are related to cognitive function: The Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC) Study
    • van Norden AG, van den Berg HA, de Laat KF, Gons RA, van Dijk EJ and de Leeuw FE. Frontal and temporal microbleeds are related to cognitive function: the Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC) Study. Stroke 2011; 42: 3382-3386
    • (2011) Stroke , vol.42 , pp. 3382-3386
    • Van Norden, A.G.1    Van Den Berg, H.A.2    De Laat, K.F.3    Gons, R.A.4    Van Dijk, E.J.5    De Leeuw, F.E.6
  • 116
    • 24344482925 scopus 로고    scopus 로고
    • Cerebral small-vessel disease and decline in information processing speed, executive function and memory
    • Prins ND, van Dijk EJ, den HT, Vermeer SE, Jolles J, Koudstaal PJ, et al. Cerebral small-vessel disease and decline in information processing speed, executive function and memory. Brain 2005; 128: 2034-2041
    • (2005) Brain , vol.128 , pp. 2034-2041
    • Prins, N.D.1    Van Dijk, E.J.2    Den, H.T.3    Vermeer, S.E.4    Jolles, J.5    Koudstaal, P.J.6
  • 117
    • 68149108650 scopus 로고    scopus 로고
    • Changes in white matter as determinant of global functional decline in older independent outpatients: Three year follow-up of LADIS (leukoaraiosis and disability) study cohort
    • Inzitari D, Pracucci G, Poggesi A, Carlucci G, Barkhof F, Chabriat H, et al. Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort. BMJ 2009; 339: b2477
    • (2009) BMJ , vol.339 , pp. b2477
    • Inzitari, D.1    Pracucci, G.2    Poggesi, A.3    Carlucci, G.4    Barkhof, F.5    Chabriat, H.6
  • 118
    • 8644231001 scopus 로고    scopus 로고
    • White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage
    • Smith EE, Gurol ME, Eng JA, Engel CR, Nguyen TN, Rosand J, et al. White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage. Neurology 2004; 63: 1606-1612
    • (2004) Neurology , vol.63 , pp. 1606-1612
    • Smith, E.E.1    Gurol, M.E.2    Eng, J.A.3    Engel, C.R.4    Nguyen, T.N.5    Rosand, J.6
  • 121
    • 0842310806 scopus 로고    scopus 로고
    • Cortical microinfarcts and demyelination significantly affect cognition in brain aging
    • Kovari E, Gold G, Herrmann FR, Canuto A, Hof PR, Michel JP, et al. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 2004; 35: 410-414
    • (2004) Stroke , vol.35 , pp. 410-414
    • Kovari, E.1    Gold, G.2    Herrmann, F.R.3    Canuto, A.4    Hof, P.R.5    Michel, J.P.6
  • 125
    • 28044442258 scopus 로고    scopus 로고
    • Damage within a network of white matter regions underlies executive dysfunction in CADASIL
    • O'Sullivan M, Barrick TR, Morris RG, Clark CA and Markus HS. Damage within a network of white matter regions underlies executive dysfunction in CADASIL. Neurology 2005; 65: 1584-1590
    • (2005) Neurology , vol.65 , pp. 1584-1590
    • O'Sullivan, M.1    Barrick, T.R.2    Morris, R.G.3    Clark, C.A.4    Markus, H.S.5
  • 126
    • 84878249805 scopus 로고    scopus 로고
    • Disruption of the cerebral white matter network is related to slowing of information processing speed in patients with type 2 diabetes
    • Utrecht Vascular Cognitive Impairment (VCI) Study Group
    • Reijmer YD, Leemans A, Brundel M, Kappelle LJ and Biessels GJ, Utrecht Vascular Cognitive Impairment (VCI) Study Group. Disruption of the cerebral white matter network is related to slowing of information processing speed in patients with type 2 diabetes. Diabetes 2013; 62: 2112-2115
    • (2013) Diabetes , vol.62 , pp. 2112-2115
    • Reijmer, Y.D.1    Leemans, A.2    Brundel, M.3    Kappelle, L.J.4    Biessels, G.J.5
  • 127
    • 47649097335 scopus 로고    scopus 로고
    • Tissue microstructural changes are independently associated with cognitive impairment in cerebral amyloid angiopathy
    • Viswanathan A, Patel P, Rahman R, Nandigam RN, Kinnecom C, Bracoud L, et al. Tissue microstructural changes are independently associated with cognitive impairment in cerebral amyloid angiopathy. Stroke 2008; 39: 1988-1992
    • (2008) Stroke , vol.39 , pp. 1988-1992
    • Viswanathan, A.1    Patel, P.2    Rahman, R.3    Nandigam, R.N.4    Kinnecom, C.5    Bracoud, L.6
  • 130
    • 84905818243 scopus 로고    scopus 로고
    • Structural network efficiency is associated with cognitive impairment in small-vessel disease
    • Lawrence AJ, Chung AW, Morris RG, Markus HS and Barrick TR. Structural network efficiency is associated with cognitive impairment in small-vessel disease. Neurology 2014; 83: 304-311
    • (2014) Neurology , vol.83 , pp. 304-311
    • Lawrence, A.J.1    Chung, A.W.2    Morris, R.G.3    Markus, H.S.4    Barrick, T.R.5
  • 131
    • 0038387609 scopus 로고    scopus 로고
    • Efficacy and tolerability of donepezil in vascular dementia: Positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial
    • Black S, Roman GC, Geldmacher DS, Salloway S, Hecker J, Burns A, et al. Efficacy and tolerability of donepezil in vascular dementia: positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial. Stroke 2003; 34: 2323-2330
    • (2003) Stroke , vol.34 , pp. 2323-2330
    • Black, S.1    Roman, G.C.2    Geldmacher, D.S.3    Salloway, S.4    Hecker, J.5    Burns, A.6
  • 132
  • 134
    • 77953151730 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, clinical trial of donepezil in vascular dementia: Differential effects by hippocampal size
    • Roman GC, Salloway S, Black SE, Royall DR, Decarli C, Weiner MW, et al. Randomized, placebo-controlled, clinical trial of donepezil in vascular dementia: differential effects by hippocampal size. Stroke 2010; 41: 1213-1221
    • (2010) Stroke , vol.41 , pp. 1213-1221
    • Roman, G.C.1    Salloway, S.2    Black, S.E.3    Royall, D.R.4    Decarli, C.5    Weiner, M.W.6
  • 136
    • 0037070773 scopus 로고    scopus 로고
    • Efficacy of galantamine in probable vascular dementia and Zleheimer's disease combined with cerebrovascular disease: A randomised trial
    • Erkinjuntti T, Kurz A, Gauthier S, Bullock R, Lilienfeld S and Damaraju CV. Efficacy of galantamine in probable vascular dementia and Zleheimer's disease combined with cerebrovascular disease: a randomised trial. Lancet 2002; 359: 1283-1290
    • (2002) Lancet , vol.359 , pp. 1283-1290
    • Erkinjuntti, T.1    Kurz, A.2    Gauthier, S.3    Bullock, R.4    Lilienfeld, S.5    Damaraju, C.V.6
  • 137
    • 53449094613 scopus 로고    scopus 로고
    • Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: The VantagE study
    • Ballard C, Sauter M, Scheltens P, He Y, Barkhof F, van Straaten EC, et al. Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study. Curr Med Res Opin 2008; 24: 2561-2574
    • (2008) Curr Med Res Opin , vol.24 , pp. 2561-2574
    • Ballard, C.1    Sauter, M.2    Scheltens, P.3    He, Y.4    Barkhof, F.5    Van Straaten, E.C.6
  • 138
    • 0036314492 scopus 로고    scopus 로고
    • Efficacy and safety of memantine in patients with mild to moderate vascular dementia: A randomized, placebo-controlled trial (MMM 300)
    • Orgogozo JM, Rigaud AS, Stoffler A, Mobius HJ and Forette F. Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300). Stroke 2002; 33: 1834-1839
    • (2002) Stroke , vol.33 , pp. 1834-1839
    • Orgogozo, J.M.1    Rigaud, A.S.2    Stoffler, A.3    Mobius, H.J.4    Forette, F.5
  • 139
    • 0036840767 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500)
    • Wilcock G, Mobius HJ and Stoffler A. A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500). Int Clin Psychopharmacol 2002; 17: 297-305
    • (2002) Int Clin Psychopharmacol , vol.17 , pp. 297-305
    • Wilcock, G.1    Mobius, H.J.2    Stoffler, A.3
  • 140
    • 77749279917 scopus 로고    scopus 로고
    • A randomized controlled trial of rivastigmine in patients with cognitive impairment no dementia because of cerebrovascular disease
    • Narasimhalu K, Effendy S, Sim CH, Lee JM, Chen I, Hia SB, et al. A randomized controlled trial of rivastigmine in patients with cognitive impairment no dementia because of cerebrovascular disease. Acta Neurol Scand 2010; 121: 217-224
    • (2010) Acta Neurol Scand , vol.121 , pp. 217-224
    • Narasimhalu, K.1    Effendy, S.2    Sim, C.H.3    Lee, J.M.4    Chen, I.5    Hia, S.B.6
  • 141
    • 10744225948 scopus 로고    scopus 로고
    • Clinical manifestations of cerebral amyloid angiopathy-related inflammation
    • Eng JA, Frosch MP, Choi K, Rebeck GW and Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol 2004; 55: 250-256
    • (2004) Ann Neurol , vol.55 , pp. 250-256
    • Eng, J.A.1    Frosch, M.P.2    Choi, K.3    Rebeck, G.W.4    Greenberg, S.M.5
  • 143
    • 84878407495 scopus 로고    scopus 로고
    • Anti-amyloid beta autoantibodies in cerebral amyloid angiopathy-related inflammation: Implications for amyloid-modifying therapies
    • Piazza F, Greenberg SM, Savoiardo M, Gardinetti M, Chiapparini L, Raicher I, et al. Anti-amyloid beta autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies. Ann Neurol 2013; 73: 449-458
    • (2013) Ann Neurol , vol.73 , pp. 449-458
    • Piazza, F.1    Greenberg, S.M.2    Savoiardo, M.3    Gardinetti, M.4    Chiapparini, L.5    Raicher, I.6
  • 144
    • 77951176094 scopus 로고    scopus 로고
    • Steroid responsive encephalopathy in cerebral amyloid angiopathy: A case report and review of evidence for immunosuppressive treatment
    • Kloppenborg RP, Richard E, Sprengers ME, Troost D, Eikelenboom P and Nederkoorn PJ. Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment. J Neuroinflammation 2010; 7: 18-2094-7-18
    • (2010) J Neuroinflammation , vol.7 , pp. 182094-182718
    • Kloppenborg, R.P.1    Richard, E.2    Sprengers, M.E.3    Troost, D.4    Eikelenboom, P.5    Nederkoorn, P.J.6
  • 145
    • 84895586050 scopus 로고    scopus 로고
    • Cerebral microbleeds are not associated with long-term cognitive outcome in patients with transient ischemic attack or minor stroke
    • Brundel M, Kwa VI, Bouvy WH, Algra A, Kappelle LJ, Biessels GJ, et al. Cerebral microbleeds are not associated with long-term cognitive outcome in patients with transient ischemic attack or minor stroke. Cerebrovasc Dis 2014; 37: 195-202
    • (2014) Cerebrovasc Dis , vol.37 , pp. 195-202
    • Brundel, M.1    Kwa, V.I.2    Bouvy, W.H.3    Algra, A.4    Kappelle, L.J.5    Biessels, G.J.6
  • 146
    • 84903220594 scopus 로고    scopus 로고
    • Brain changes underlying cognitive dysfunction in diabetes: What can we learn from MRI
    • Biessels GJ and Reijmer YD. Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI? Diabetes 2014; 63: 2244-2252
    • (2014) Diabetes , vol.63 , pp. 2244-2252
    • Biessels, G.J.1    Reijmer, Y.D.2
  • 147
    • 84895797508 scopus 로고    scopus 로고
    • Accumulation of MRI Markers of Cerebral Small Vessel Disease is Associated with Decreased Cognitive Function. A Study in First-Ever Lacunar Stroke and Hypertensive Patients
    • Huijts M, Duits A, van Oostenbrugge RJ, Kroon AA, de Leeuw PW and Staals J. Accumulation of MRI Markers of Cerebral Small Vessel Disease is Associated with Decreased Cognitive Function. A Study in First-Ever Lacunar Stroke and Hypertensive Patients. Front Aging Neurosci 2013; 5: 72
    • (2013) Front Aging Neurosci , vol.5 , pp. 72
    • Huijts, M.1    Duits, A.2    Van Oostenbrugge, R.J.3    Kroon, A.A.4    De Leeuw, P.W.5    Staals, J.6
  • 149
    • 84871216609 scopus 로고    scopus 로고
    • Incident subcortical infarcts induce focal thinning in connected cortical regions
    • Duering M, Righart R, Csanadi E, Jouvent E, Herve D, Chabriat H, et al. Incident subcortical infarcts induce focal thinning in connected cortical regions. Neurology 2012; 79: 2025-2028
    • (2012) Neurology , vol.79 , pp. 2025-2028
    • Duering, M.1    Righart, R.2    Csanadi, E.3    Jouvent, E.4    Herve, D.5    Chabriat, H.6
  • 150
    • 73449087958 scopus 로고    scopus 로고
    • Red meets white: Do microbleeds link hemorrhagic and ischemic cerebrovascular disease
    • Kidwell CS and Greenberg SM. Red meets white: do microbleeds link hemorrhagic and ischemic cerebrovascular disease? Neurology 2009; 73: 1614-1615
    • (2009) Neurology , vol.73 , pp. 1614-1615
    • Kidwell, C.S.1    Greenberg, S.M.2
  • 151
    • 84921968415 scopus 로고    scopus 로고
    • Cerebral microbleeds: Where are we now
    • Fisher M. Cerebral microbleeds: where are we now. Neurology 2014; 83: 1304-1305
    • (2014) Neurology , vol.83 , pp. 1304-1305
    • Fisher, M.1
  • 152
    • 84855353967 scopus 로고    scopus 로고
    • Blood pressure reduction, decreased diffusion on MRI, and outcomes after intracerebral hemorrhage
    • Garg RK, Liebling SM, Maas MB, Nemeth AJ, Russell EJ and Naidech AM. Blood pressure reduction, decreased diffusion on MRI, and outcomes after intracerebral hemorrhage. Stroke 2012; 43: 67-71
    • (2012) Stroke , vol.43 , pp. 67-71
    • Garg, R.K.1    Liebling, S.M.2    Maas, M.B.3    Nemeth, A.J.4    Russell, E.J.5    Naidech, A.M.6
  • 153
    • 0032735996 scopus 로고    scopus 로고
    • Early alterations in cerebral hemodynamics, brain metabolism, and bloodbrain barrier permeability in experimental intracerebral hemorrhage
    • Lee EJ, Hung YC and Lee MY. Early alterations in cerebral hemodynamics, brain metabolism, and bloodbrain barrier permeability in experimental intracerebral hemorrhage. J Neurosurg 1999; 91: 1013-1019
    • (1999) J Neurosurg , vol.91 , pp. 1013-1019
    • Lee, E.J.1    Hung, Y.C.2    Lee, M.Y.3
  • 154
    • 0036715094 scopus 로고    scopus 로고
    • Intracerebral hemorrhage triggers interleukin-6 and interleukin-10 release in blood
    • Dziedzic T, Bartus S, Klimkowicz A, Motyl M, Slowik A and Szczudlik A. Intracerebral hemorrhage triggers interleukin-6 and interleukin-10 release in blood. Stroke 2002; 33: 2334-2335
    • (2002) Stroke , vol.33 , pp. 2334-2335
    • Dziedzic, T.1    Bartus, S.2    Klimkowicz, A.3    Motyl, M.4    Slowik, A.5    Szczudlik, A.6
  • 155
    • 73449094851 scopus 로고    scopus 로고
    • Rapid appearance of new cerebral microbleeds after acute ischemic stroke
    • Jeon SB, Kwon SU, Cho AH, Yun SC, Kim JS and Kang DW. Rapid appearance of new cerebral microbleeds after acute ischemic stroke. Neurology 2009; 73: 1638-1644
    • (2009) Neurology , vol.73 , pp. 1638-1644
    • Jeon, S.B.1    Kwon, S.U.2    Cho, A.H.3    Yun, S.C.4    Kim, J.S.5    Kang, D.W.6
  • 157
    • 60549098398 scopus 로고    scopus 로고
    • Vascular risk factors and dementia: How to move forward
    • Viswanathan A, Rocca WA and Tzourio C. Vascular risk factors and dementia: how to move forward? Neurology 2009; 72: 368-374
    • (2009) Neurology , vol.72 , pp. 368-374
    • Viswanathan, A.1    Rocca, W.A.2    Tzourio, C.3
  • 158
    • 33646183346 scopus 로고    scopus 로고
    • Altered diffusion tensor in multiple sclerosis normal-appearing brain tissue: Cortical diffusion changes seem related to clinical deterioration
    • Vrenken H, Pouwels PJ, Geurts JJ, Knol DL, Polman CH, Barkhof F, et al. Altered diffusion tensor in multiple sclerosis normal-appearing brain tissue: cortical diffusion changes seem related to clinical deterioration. J Magn Reson Imaging 2006; 23: 628-636
    • (2006) J Magn Reson Imaging , vol.23 , pp. 628-636
    • Vrenken, H.1    Pouwels, P.J.2    Geurts, J.J.3    Knol, D.L.4    Polman, C.H.5    Barkhof, F.6
  • 159
    • 84920603179 scopus 로고    scopus 로고
    • Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits
    • Ward AM, Mormino EC, Huijbers W, Schultz AP, Hedden T and Sperling RA. Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits. Neurobiol Aging 2014; 36: 265-272
    • (2014) Neurobiol Aging , vol.36 , pp. 265-272
    • Ward, A.M.1    Mormino, E.C.2    Huijbers, W.3    Schultz, A.P.4    Hedden, T.5    Sperling, R.A.6
  • 160
    • 84925271308 scopus 로고    scopus 로고
    • Beyond BOLD: Optimizing functional imaging in stroke populations
    • Veldsman M, Cumming T and Brodtmann A. Beyond BOLD: optimizing functional imaging in stroke populations. Hum Brain Mapp 2015; 36: 1620-1636.
    • (2015) Hum Brain Mapp , vol.36 , pp. 1620-1636
    • Veldsman, M.1    Cumming, T.2    Brodtmann, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.