Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients

Alzheimer's and Dementia

Volumn 11, Issue 12, 2015, Pages 1500-1509

  Van Veluw, Susanne J ^a   Hilal, Saima ^b,c   Kuijf, Hugo J ^d   Ikram, Mohammad Kamran ^b,c   Xin, Xu ^b,c   Yeow, Tan Boon ^e   Venketasubramanian, Narayanaswamy ^f   Biessels, Geert Jan ^a   Chen, Christopher ^b,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e St Luke's Hospital   (Singapore)

^f RAFFLES HOSPITAL   (Singapore)

Author keywords

Alzheimer's disease; Atrophy; Dementia; Memory clinic population; Microinfarcts; MRI; Small vessel disease

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; CLINICAL FEATURE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATIONAL STUDY; DEMOGRAPHY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; FEMALE; HOSPITAL; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MEMORY CLINIC; MINI MENTAL STATE EXAMINATION; MONTREAL COGNITIVE ASSESSMENT; MULTIINFARCT DEMENTIA; NEUROIMAGING; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; SINGAPORE; ALZHEIMER DISEASE; CEREBRAL INFARCTION; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PHYSIOLOGY; PROCEDURES; VASCULARIZATION;

AGED; ALZHEIMER DISEASE; CEREBRAL CORTEX; CEREBRAL INFARCTION; DEMENTIA, VASCULAR; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS;

EID: 84949481033     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2014.12.010     Document Type: Article

References (41)

1. S.T. Pendlebury, and P.M. Rothwell Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis Lancet Neurol 8 2009 1006 1018
2. R.N. Kalaria, R.A. Kenny, C.G. Ballard, R. Perry, P. Ince, and T. Polvikoski Towards defining the neuropathological substrates of vascular dementia J Neurol Sci 226 2004 75 80
3. L. Pantoni Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges Lancet Neurol 9 2010 689 701
4. J.M. Wardlaw, E.E. Smith, G.J. Biessels, C. Cordonnier, F. Fazekas, R. Frayne, and et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration Lancet Neurol 12 2013 822 838
5. E.E. Smith, J.A. Schneider, J.M. Wardlaw, and S.M. Greenberg Cerebral microinfarcts: the invisible lesion Lancet Neurol 11 2012 272 282
6. M. Brundel, J. de Bresser, J.J. van Dillen, L.J. Kappelle, and G.J. Biessels Cerebral microinfarcts: a systematic review of neuropathological studies J Cereb Blood Flow Metab 32 2012 425 436
7. L.J. Launer, T.M. Hughes, and L.R. White Microinfarcts, brain atrophy, and cognitive function: the Honolulu Asia Aging Study Autopsy Study Ann Neurol 70 2011 774 780
8. Z. Arvanitakis, S.E. Leurgans, L.L. Barnes, D.A. Bennett, and J.A. Schneider Microinfarct pathology, dementia, and cognitive systems Stroke 42 2011 722 727
9. S.J. Van Veluw, J.J. Zwanenburg, J. Engelen-Lee, W.G. Spliet, J. Hendrikse, P.R. Luijten, and et al. In vivo detection of cerebral cortical microinfarcts with high-resolution 7T MRI J Cereb Blood Flow Metab 33 2013 322 329
10. Y. Ii, M. Maeda, H. Kida, K. Matsuo, A. Shindo, A. Taniguchi, and et al. In vivo detection of cortical microinfarcts on ultrahigh-field MRI J Neuroimaging 23 2013 28 32
11. G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease Neurology 34 1984 939 944
12. S. Wiederkehr, M. Simard, C. Fortin, and R. van Reekum Validity of the clinical diagnostic criteria for vascular dementia: a critical review J Neuropsychiatry Clin Neurosci 20 2008 150 177
13. D. Yeo, C. Gabriel, C. Chen, S. Lee, T. Loenneker, and M. Wong Pilot validation of a customized neuropsychological battery in elderly Singaporeans Neurol J South East Asia 123 1997 1 8
14. B. Dubois, A. Slachevsky, I. Litvan, and B. Pillon The FAB: a frontal assessment battery at bedside Neurology 55 2000 1621 1626
15. S.D. Porteus The Maze test and clinical psychology 1959 Pacific Books Palo Alto, CA
16. D. Wechsler Wechsler Memory Scale - revised 3rd Ed. 1997 Jovanovich San Antonio, TX
17. R.F. Lewis, and P.M. Rennick Manual for the repeatable cognitive perceptual-motor battery 1979 Axon Clinton Township, MI
18. W.J. Mack, D.M. Freed, B.W. Williams, and V.W. Henderson Boston Naming Test: shortened versions for use in Alzheimer's disease J Gerontol 47 1992 154 158
19. B. Isaacs, and A.T. Kennie The set test as an aid to the detection of dementia in old people Br J Psychiatry 123 1973 467 470
20. S. Sahadevan, P.P. Lim, N.J. Tan, and S.P. Chan Diagnostic performance of two mental status tests in the older Chinese: influence of education and age on cut-off values Int J Geriatr Psychiatry 15 2000 234 241
21. T. Sunderland, J.L. Hill, A.M. Mellow, B.A. Lawlor, J. Gundersheimer, P.A. Newhouse, and et al. Clock drawing in Alzheimer's disease. A novel measure of dementia severity J Am Geriatr Soc 7 1989 725 729
22. D. Wechsler Wechsler Adult Intelligence Scale - revised 1981 Harcourt Brace Jovanovich San Antonio, TX
23. A. Smith Symbol Digit Modalities Test 1973 The American Psychiatric Pub Los Angeles, CA
24. L. Diller, Y. Ben-Yishay, and L.J. Gerstman Studies in cognition and rehabilitation in hemiplegia 1974 New York University Medical Center Institute of Rehabilitation Medicine New York
25. S.J. Van Veluw, S.M. Heringa, H.J. Kuijf, H.L. Koek, P.R. Luijten, and G.J. Biessels Cerebral cortical microinfarcts at 7Tesla MRI in patients with early Alzheimer's disease J Alzheimers Dis 39 2014 163 167
26. H.J. Kuijf, S.J. van Veluw, M.A. Viergever, K.L. Vincken, and G.J. Biessels How to assess the reliability of cerebral microbleed rating? Front Aging Neurosci 26 2013 57
27. F. Ritter, T. Boskamp, A. Homeyer, H. Laue, M. Schwier, F. Link, and et al. Medical image analysis: a visual approach IEEE Pulse 2 2011 60 70
28. H.J. Kuijf Image processing techniques for quantification and assessment of brain MRI 2013 Utrecht University Utrecht, the Netherlands
29. J. Ashburner, and K.J. Friston Unified segmentation Neuroimage 26 2005 839 851
30. S. Van Rooden, J.D. Goos, A.M. van Opstal, M.J. Versluis, A.G. Webb, G.J. Blauw, and et al. Increased number of microinfarcts in Alzheimer disease at 7-T MR imaging Radiology 270 2013 205 211
31. M.B. Westover, M.T. Bianchi, C. Yang, J.A. Schneider, and S.M. Greenberg Estimating cerebral microinfarct burden from autopsy samples Neurology 80 2013 1365 1369
32. L. Yu, P.A. Boyle, S. Leurgans, J.A. Schneider, and D.A. Bennett Disentangling the effects of age and APOE on neuropathology and late life cognitive decline Neurobiol Aging 35 2014 819 826
33. W.T. Longstreth Jr., J.A. Sonnen, T.D. Koepsell, W.A. Kukull, E.B. Larson, and T.J. Montine Associations between microinfarcts and other macroscopic vascular findings on neuropathologic examination in 2 databases Alzheimer Dis Assoc Disord 23 2009 291 294
34. J.C. Troncoso, A.B. Zonderman, S.M. Resnick, B. Crain, O. Pletnikova, and R.J. O'Brien Effect of infarcts on dementia in the Baltimore Longitudinal Study of Aging Ann Neurol 64 2008 168 176
35. L.Y. Wang, E.B. Larson, J.A. Sonnen, J.B. Shofer, W. McCormick, J.D. Bowen, and et al. Blood pressure and brain injury in older adults: findings from a community-based autopsy study J Am Geriatr Soc 57 2009 1975 1981
36. J.A. Schneider, P.A. Boyle, Z. Arvanitakis, J.L. Bienias, and D.A. Bennett Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons Ann Neurol 62 2007 59 66
37. E. Kövari, F.R. Herrmann, P.R. Hof, and C. Bouras The relationship between cerebral amyloid angiopathy and cortical microinfarcts in brain ageing and Alzheimer's disease Neuropathol Appl Neurobiol 39 2013 498 509
38. V. Soontornniyomkij, M.D. Lynch, S. Mermash, J. Pomakian, H. Badkoobehi, R. Clare, and et al. Cerebral microinfarcts associated with severe cerebral beta-amyloid angiopathy Brain Pathol 20 2010 459 467
39. M. Haglund, U. Passant, M. Sjobeck, E. Ghebremedhin, and E. Englund Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia Int J Geriatr Psychiatry 21 2006 681 687
40. L. Zheng, H.V. Vinters, W.J. Mack, C. Zarow, W.G. Ellis, and HC. Chui Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes Stroke 44 2013 2835 2841
41. S.J. Van Veluw, W.M. Jolink, J. Hendrikse, M.I. Geerlings, P.R. Luijten, G.J. Biessels, and et al. Cortical microinfarcts on 7T MRI in patients with spontaneous intracerebral hemorrhage J Cereb Blood Flow Metab 34 2014 1104 1106