Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization

Journal of the American Chemical Society

Volumn 137, Issue 49, 2015, Pages 15398-15401

  Nguyen, Giang K T ^a   Kam, Antony ^a   Loo, Shining ^a   Jansson, Anna E ^a   Pan, Lucy X ^a   Tam, James P ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIZATION; PEPTIDES;

CYCLIZATIONS; DRUG DESIGN; EFFICIENT STRATEGY; MACRO-CYCLIZATION; MACROCYCLES; PROTEIN ENGINEERING; SORTASE A;

PROTEINS;

APELIN; BUTELASE 1; CARBOXYPEPTIDASE A; EXOPEPTIDASE; GALANIN; GREEN FLUORESCENT PROTEIN; HUMAN GROWTH HORMONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LIGASE; NEUROMEDIN U; PEPTIDE; PROTEIN; SORTASE; UNCLASSIFIED DRUG; PEPTIDE SYNTHASE; PLANT PROTEIN;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYCLIZATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INCUBATION TIME; KINETIC PARAMETERS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN STABILITY; TANDEM MASS SPECTROMETRY; TEMPERATURE SENSITIVITY; THERMOSTABILITY; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; RAT;

AMINO ACID SEQUENCE; ANIMALS; CYCLIZATION; HUMANS; LIGASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE SYNTHASES; PEPTIDES; PLANT PROTEINS; PROTEINS; RATS;

EID: 84950282620     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b11014     Document Type: Article

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