Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17598-17607

  Nguyen, Giang Kien Truc ^a   Lim, Wei Han ^a   Nguyen, Phuong Quoc Thuc ^a   Tam, James P ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOTIDES; CYTOTOXIC; DIVERSE RANGE; ENZYMATIC DEGRADATION; GENETIC CHARACTERIZATION; HEMOLYTIC ACTIVITY; HYDROPHOBIC PATCH; METHIONINE OXIDATION; NATURALLY OCCURRING; RUBIACEAE; SINGLE SPECIES; THERAPEUTIC POTENTIALS;

AMINO ACIDS; DEGRADATION; GENES;

BIOACTIVITY;

ANTIINFECTIVE AGENT; CHASSALIA CHARTACEA EXTRACT; CHASSATIDE C1; CHASSATIDE C10; CHASSATIDE C11; CHASSATIDE C11A; CHASSATIDE C12; CHASSATIDE C13; CHASSATIDE C14; CHASSATIDE C15; CHASSATIDE C16; CHASSATIDE C17; CHASSATIDE C18; CHASSATIDE C2; CHASSATIDE C2A; CHASSATIDE C3; CHASSATIDE C4; CHASSATIDE C5; CHASSATIDE C6; CHASSATIDE C7; CHASSATIDE C8; CHASSATIDE C9; CYCLOTIDE; CYTOTOXIC AGENT; HEMOLYTIC AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG; UNCYCLOTIDE;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CHASSALIA CHARTACEA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; GENETIC ANALYSIS; HEDYOTIS; HEMOLYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; METHIONINE OXIDATION; NONHUMAN; OXIDATION; PLANT GENE; PRIORITY JOURNAL; RUBIACEAE;

ANTI-BACTERIAL AGENTS; BACTERIA; BASE SEQUENCE; CYCLOTIDES; METHIONINE; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PLANT PROTEINS; RUBIACEAE;

CHASSALIA; CHASSALIA CHARTACEA; HEDYOTIS; RUBIACEAE;

EID: 84861204779     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.338970     Document Type: Article

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