Sortase-catalyzed transformations that improve the properties of cytokines

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 8, 2011, Pages 3169-3174

  Popp, Maximilian W ^a,b   Dougan, Stephanie K ^a   Chuang, Tzu Ying ^a   Spooner, Eric ^a   Ploegh, Hidde L ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTERFERON; CYTOKINE; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; GLYCOPEPTIDASE; GLYCOPROTEIN; MACROGOL; POLYPEPTIDE; SORTASE;

AMINO TERMINAL SEQUENCE; ARTICLE; ASYMMETRIC CATALYSIS; BIOLOGICAL ACTIVITY; BIOTRANSFORMATION; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; COVALENT BOND; CYCLIZATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME MECHANISM; HALF LIFE TIME; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN STRUCTURE; RECEPTOR BINDING; TANDEM MASS SPECTROMETRY; THERMOSTABILITY; TRANSPEPTIDATION;

AMINOACYLTRANSFERASES; ANIMALS; BACTERIAL PROTEINS; CATALYSIS; CYCLIZATION; CYSTEINE ENDOPEPTIDASES; CYTOKINES; HALF-LIFE; METHODS; MICE; POLYETHYLENE GLYCOLS; PROTEIN STABILITY; STREPTOCOCCUS PYOGENES;

EID: 79952768710     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016863108     Document Type: Article

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