Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function

Cardiovascular Diabetology

Volumn 14, Issue 1, 2015, Pages

  Hodson, Aimee E ^a   Tippetts, Trevor S ^a   Bikman, Benjamin T ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Ceramide; Hyperinsulinemia; Insulin; Mitochondria

Indexed keywords

CERAMIDE; INSULIN; THERMOZYMOCIDIN; ANTIDIABETIC AGENT; MONOUNSATURATED FATTY ACID;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOENERGY; CARDIOMETABOLIC RISK; CARDIOVASCULAR DISEASE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HEART MUSCLE; HEART MUSCLE CELL; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN SYNTHESIS; RISK FACTOR; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE CELL; CELL LINE; CELL RESPIRATION; CHEMICALLY INDUCED; DRUG EFFECTS; ENERGY METABOLISM; HEART MITOCHONDRION; HYPERINSULINISM; METABOLISM; RAT; TIME FACTOR; WEIGHT GAIN;

ANIMALS; CELL LINE; CELL RESPIRATION; CERAMIDES; ENERGY METABOLISM; FATTY ACIDS, MONOUNSATURATED; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MALE; MICE, INBRED C57BL; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; RATS; TIME FACTORS; WEIGHT GAIN;

EID: 84950135922     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-015-0316-y     Document Type: Article

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