G-protein-gated inwardly rectifying potassium channels modulate respiratory depression by Opioids

Anesthesiology

Volumn 124, Issue 3, 2016, Pages 641-650

  Montandon, Gaspard ^a   Ren, Jun ^b   Victoria, Nicole C ^c   Liu, Hattie ^a   Wickman, Kevin ^c   Greer, John J ^b   Horner, Richard L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; FLUPIRTINE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 2; MU OPIATE RECEPTOR; OPIATE; POTASSIUM CHANNEL BLOCKING AGENT; TERTIAPIN Q; UNCLASSIFIED DRUG; BEE VENOM; KCNJ6 PROTEIN, MOUSE; NARCOTIC ANALGESIC AGENT; TERTIAPIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING; BREATHING RATE; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SUBUNIT; RAT; RESPIRATION DEPRESSION; ROSTRAL VENTROLATERAL MEDULLA; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; RESPIRATORY FAILURE; WISTAR RAT;

ANALGESICS, OPIOID; ANIMALS; BEE VENOMS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; MALE; MICE; MICE, KNOCKOUT; RATS; RATS, WISTAR; RECEPTORS, OPIOID, MU; RESPIRATORY INSUFFICIENCY;

EID: 84950126032     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000984     Document Type: Article

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