Spinal G-Protein-Gated K+ Channels Formed by GIRK1 and GIRK2 Subunits Modulate Thermal Nociception and Contribute to Morphine Analgesia

Journal of Neuroscience

Volumn 24, Issue 11, 2004, Pages 2806-2812

  Marker, Cheryl L ^a   Stoffel, Markus ^b   Wickman, Kevin ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Kir3; Knock out; Opioid; Pain; Potassium; Tail flick

Indexed keywords

MORPHINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TERTIAPIN; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ABUSE; DRUG MEGADOSE; FEMALE; G PROTEIN GATED INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT 1; G PROTEIN GATED INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT 2; G PROTEIN GATED INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT 3; G PROTEIN GATED POTASSIUM CHANNEL; KNOCKOUT GENE; MOUSE; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD DORSAL HORN; TAIL FLICK TEST; THERMAL STIMULATION; TISSUE DISTRIBUTION;

ANALGESIA; ANIMALS; BEE VENOMS; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GTP-BINDING PROTEINS; HEAT; HYPERALGESIA; INJECTIONS, SPINAL; ION CHANNEL GATING; MALE; MICE; MICE, KNOCKOUT; MORPHINE; PAIN; PAIN MEASUREMENT; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN SUBUNITS; SEX FACTORS;

EID: 1642290744     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5251-03.2004     Document Type: Article

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