Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents

Pharmaceutical Biology

Volumn 54, Issue 1, 2016, Pages 105-110

  Miri, Ramin ^a   Nejati, Maryam ^a   Saso, Luciano ^b   Khakdan, Fatemeh ^a   Parshad, Badri ^c   Mathur, Divya ^c   Parmar, Virinder S ^c,d   Bracke, Marc E ^d   Prasad, Ashok K ^c   Sharma, Sunil K ^c   Firuzi, Omidreza ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF DELHI   (India)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Cancer; cell; cytotoxic; methylcoumarins; MTT

Indexed keywords

4 METHYLCOUMARIN DERIVATIVE; 6 BROMO 4 BROMOMETHYL 7 HYDROXYCOUMARIN DERIVATIVE; 7 ACETOXY 4 METHYLCOUMARIN DERIVATIVE; 7 HYDROXY 4 METHYLCOUMARIN DERIVATIVE; ANTINEOPLASTIC AGENT; COUMARIN DERIVATIVE; DIACETOXY 4 METHYLCOUMARIN DERIVATIVE; DIHYDROXY 4 METHYLCOUMARIN DERIVATIVE; PROTEIN BAD; PROTEIN BAK; PROTEIN BCL XL; PROTEIN BID; PROTEIN MCL 1; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL LINE; CELL VIABILITY; CHRONIC MYELOID LEUKEMIA; COLON ADENOCARCINOMA; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG PENETRATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LIPOPHILICITY; M PHASE CELL CYCLE CHECKPOINT; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; UPREGULATION; CELL SURVIVAL; CHEMICAL STRUCTURE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; IC50; K562 CELL LINE; MCF 7 CELL LINE; METHYLATION; NEOPLASMS; PATHOLOGY; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL SURVIVAL; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; MCF-7 CELLS; METHYLATION; MOLECULAR STRUCTURE; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84949908491     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2015.1016183     Document Type: Article

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