Human acute promyelocytic leukemia NB4 cells are sensitive to esculetin through induction of an apoptotic mechanism

Chemico-Biological Interactions

Volumn 220, Issue , 2014, Pages 129-139

  Rubio, Virginia ^a   Calviño, Eva ^a   García Pérez, Ana ^a   Herráez, Angel ^a   Diez, José C ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Apoptosis; Caspases; Intracellular kinases; Leukemia; Peroxides; Superoxides

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DNA; ESCULETIN; FLUORESCEIN ISOTHIOCYANATE; GLUTATHIONE; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; CELL DNA; PROTEIN KINASE B; ANTIOXIDANT; UMBELLIFERONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DIPLOIDY; DNA FRAGMENTATION; DNA SYNTHESIS; DRUG CYTOTOXICITY; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; NB4 CELL LINE; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL ASSAY; CELL CYCLE PROGRESSION; CHEMOSENSITIVITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; PROTEIN SECRETION; SENSITIVITY ANALYSIS; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; LEUKEMIA, PROMYELOCYTIC, ACUTE; TIME; WESTERN BLOTTING;

ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; TIME FACTORS; UMBELLIFERONES;

EID: 84904323230     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.06.021     Document Type: Article

References (43)

1. J.D. Rowley, H.M. Golomb, J. Vardiman, S. Fukuhara, C. Dougherty, and D. Potter Further evidence for a non-random chromosomal abnormality in acute promyelocytic leukaemia Int. J. Cancer 20 1977 869 872 (Pubitemid 8235944)
2. A. Melnick, and J.D. Licht Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukaemia Blood 93 1999 3167 3215 (Pubitemid 29220886)
3. H.G. Drexler, H. Quentmeier, R.A.F. MacLeod, C.C. Uphoff, and Z.B. Hu Leukemia cell lines: in vitro models for the study of acute promyelocytic leukaemia Leuk. Res. 19 1995 681 691
4. M. Lanotte, V. Martin-Thouvenin, S. Najman, P. Balerini, F. Valensi, and R. Berger NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3) Blood 77 1991 1080 1086
5. L. Maksumova, K. Ohnishi, F. Muratkhodjaev, W. Zhang, L. Pan, A. Takeshita, and R. Ohno Increased sensitivity of multidrug-resistant myeloid leukemia cell lines to lovastatin Leukemia 14 2000 1444 1450 (Pubitemid 30599325)
6. J.G. Jurcic, S.L. Soignet, and A.P. Maslak Diagnosis and treatment of acute promyelocytic leukaemia Curr. Oncol. Rep. 9 2007 337 344 (Pubitemid 47377064)
7. F. Lo-Coco, E. Ammatuna, P. Montesinos, and M.A. Sanz Acute promyelocytic leukemia: recent advances in diagnosis and management Semin. Oncol. 35 2008 401 409
8. J.L. Slack, S. Waxman, G. Tricot, M.S. Tallman, and C.D. Bloomfield Advances in the management of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide Oncologist 7 2002 1 13 (Pubitemid 34293055)
9. P. Sancho, E. Galeano, E. Nieto, M.D. Delgado, and A.I. García-Pérez Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production Leuk. Res. 7 2007 969 978 (Pubitemid 46856728)
10. A.I. García-Pérez, E. Galeano, E. Nieto, and P. Sancho Dequalinium induces human leukemia cell death by affecting the redox balance Leuk. Res. 35 2011 1395 1401
11. E. Calviño, J.L. Manjón, P. Sancho, M.C. Tejedor, A. Herráez, and J.C. Diez Ganoderma lucidum induced apoptosis in NB4 human leukaemia cells: involvement of Akt and Erk J. Ethnopharmacol. 178 2010 71 78
12. E. Calviño, L. Pajuelo, J.A. Ochoa de Eribe Casas, J.L. Manjon, M.C. Tejedor, A. Herraez, M. Díez Alonso, and J.C. Diez Cytotoxic action of Ganoderma lucidum on interleukin-3 dependent lymphoma DA-1 cells: involvement of apoptosis proteins Phytother. Res. 25 2011 25 32
13. D. Morales-Cano, E. Calviño, V. Rubio, A. Herráez, P. Sancho, M.C. Tejedor, and J.C. Diez Apoptosis induced by paclitaxel via Bcl-2, Bax and caspases 3 and 9 activation in NB4 human leukaemia cells is not modulated by ERK inhibition Exp. Toxicol. Pathol. 65 2013 1101 1108
14. F. Borges, F. Roleira, N. Milhazes, L. Santana, and E. Uriarte Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity Curr. Med. Chem. 12 2005 887 916 (Pubitemid 40443846)
15. K. Sekiya, H. Okuda, and S. Arich Selective inhibition of platelet lipoxygenase by esculetin Biochim. Biophys. Acta 713 1982 68 72 (Pubitemid 13206455)
16. Y. Masamoto, H. Ando, Y. Murata, Y. Shimoishi, M. Tada, and K. Takahata Mushroom tyrosinase inhibitory activity of esculetin isolated from seeds of Euphorbia lathyris L Biosci. Biotechnol. Biochem. 67 2003 631 634 (Pubitemid 39251963)
17. S.H. Kim, K.A. Kang, R. Zhang, M.J. Piao, D.O. Ko, Z.H. Wang, S.W. Chae, S.S. Kang, K.H. Lee, H.K. Kang, H.W. Kang, and W. Hyun Protective effect of esculetin against oxidative stress-induced cell damage via scavenging reactive oxygen species Acta Pharmacol. Sin. 29 2008 1319 1326
18. T. Kaneko, S. Tahara, and F. Takabayashi Suppression of lipid hydroperoxide-induced oxidative damage to cellular DNA by esculetin Biol. Pharm. Bull. 26 2003 840 844 (Pubitemid 39655305)
19. T. Kaneko, S. Tahara, and F. Takabayashi Inhibitory effect of natural coumarin compounds, esculetin and esculin, on oxidative DNA damage and formation of aberrant crypt foci and tumors induced by 1,2-dimethylhydrazine in rat colons Biol. Pharm. Bull. 30 2007 2052 2057 (Pubitemid 350097038)
20. K.C. Fylaktakidou, D.J. Hadjipavlou-Litina, K.E. Litinas, and D.N. Nicolaides Natural and synthetic coumarin derivatives with anti-inflammatory/ antioxidant activities Curr. Pharm. Des. 10 2004 3813 3833 (Pubitemid 39409872)
21. J.Y. Yang, M.A. Della-Fera, D.L. Hartzell, C. Nelson-Dooley, D.B. Hausman, and C.A. Baile Esculetin induces apoptosis and inhibits adipogenesis in 3T3-L1 cells Obesity 14 2006 1691 1699 (Pubitemid 46214790)
22. C. Park, C.Y. Jin, G.Y. Kim, I.W. Choi, T.K. Kwon, B.T. Choi, S.J. Lee, W.H. Lee, and Y.H. Choi Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK Toxicol. Appl. Pharmacol. 227 2008 219 228 (Pubitemid 351231936)
23. C. Park, C.Y. Jin, H.J. Kwon, H.J. Hwang, G.Y. Kim, I.W. Choi, T.K. Know, B.W. Kim, W.J. Kim, and Y.H. Choi Induction of apoptosis by esculetin in human leukaemia U937 cells: roles of Bcl-2 and extracellular-regulated kinase signalling Toxicol. in Vitro 24 2010 486 494
24. C.Y. Chu, Y.Y. Tsai, C.J. Wang, W.L. Lin, and T.H. Tseng Induction of apoptosis by esculetin in human leukemia cells Eur. J. Pharmacol. 416 2001 25 32
25. S.H. Kok, C.C. Yeh, M.L. Chen, and M.Y. Kuo Esculetin enhances TRAIL-induced apoptosis through DR5 upregulation in human oral cancer SAS cells Oral Oncol. 45 2009 1067 1072
26. J.T. Lee, and J.A. McCubrey The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukaemia Leukemia 16 2002 486 507 (Pubitemid 34449728)
27. G.L. Johnson, and R. Lapadat Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 298 2002 1911 1912 (Pubitemid 35425238)
28. G. Kroemer, L. Galluzi, and C. Brenner Mitochondrial membrane permeabilization in cell death Physiol. Rev. 87 2007 99 163 (Pubitemid 46209992)
29. S. Elmore Apoptosis: a review of programmed cell death Toxicol. Pathol. 35 2007 495 516 (Pubitemid 46911891)
30. A.D. Schimmer Apoptosis in leukaemia: from molecular pathways to targeted therapies Best Pract. Res. 1 2008 5 11 (Pubitemid 351377507)
31. S. Fulda Cell death in hematological tumors Apoptosis 14 2009 409 423
32. H.C. Kuo, H.J. Lee, C.C. Hu, and H.I. Tseng Enhancement of esculetin on Taxol-induced apoptosis in human hepatoma HepG2 cells Toxicol. Appl. Pharmacol. 210 2006 55 62
33. H. Pelicano, D. Carney, and P. Huang ROS stress in cancer cells and therapeutic implications Drug Resist. Updat. 7 2004 97 110 (Pubitemid 38736063)
34. J. Yang, Y.L. Xiao, X.R. He, G.F. Qiu, and X.M. Hu Aesculetin-induced apoptosis though a ROS-mediated mitochondrial dysfunction pathway in human cervical cancer cells J. Asian Nat. Prod. Res. 12 2010 185 193
35. C.J. Wang, Y.J. Hsieh, C.Y. Chu, Y.L. Lin, and T.H. Tseng Inhibition of cell cycle progression in human leukemia HL-60 cells by esculetin Cancer Lett. 183 2002 163 168
36. S.H. Lee, C. Park, C.Y. Jin, G.Y. Kim, S.K. Moon, J.W. Hyun, W.H. Lee, B.T. Choi, T.K. Kwon, Y.H. Yoo, and Y.H. Choi Involvement of extracellular signal-related kinase signaling in esculetin induced G1 arrest of human leukemia U937 cells Biomed. Pharmacother. 62 2008 723 729
37. J.Y. Yang, M.A. Della-Fera, and C.A. Baile Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes Apoptosis 11 2006 1371 1378 (Pubitemid 44035948)
38. T.H. Lin, F.J. Lu, Y.F. Yin, and T.H. Tseng Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells Chem. Biol. Interact. 180 2009 61 68
39. S. Cagnol, and J.-C. Chambard ERK and cell death: mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence FEBS J. 277 2010 2 21
40. J. Wu, W.W. Wong, F. Khosravi, M.D. Minden, and L.Z. Penn Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis Cancer Res. 64 2004 6461 6468 (Pubitemid 39297901)
41. J. Chiu, and I.W. Dawes Redox control of cell proliferation Trends Cell Biol. 22 2012 592 601
42. P. Ramyaa, R. Krishnaswamy, and V.V. Padma Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - up regulation of Nrf2 expression and down regulation of NF-κB and COX-2 Biochim. Biophys. Acta 2013 1840 681 692
43. B. Han, Y. Ren, L. Guan, W. Wei, F. Hua, and Y. Yang Sodium selenite induces apoptosis in acute promyelocytic leukaemia-derived NB4 cells through mitochondria-dependent pathway Oncol. Res. 17 2009 373 381