-
2
-
-
33645513821
-
Metal complexes in medicinal chemistry: New vistas and challenge in drug design
-
K.H. Thompson, C. Orvig. Metal complexes in medicinal chemistry: New vistas and challenge in drug design. Dalton Trans. (2006) 761e764.
-
(2006)
Dalton Trans.
, pp. 761-764
-
-
Thompson, K.H.1
Orvig, C.2
-
3
-
-
35548943504
-
Developing new metal-based therapeutics: Challenges and opportunities
-
T.W. Hambley. Developing new metal-based therapeutics: Challenges and opportunities. Dalton Trans. (2007) 4929e4937.
-
(2007)
Dalton Trans.
, pp. 4929-4937
-
-
Hambley, T.W.1
-
5
-
-
0014691619
-
Platinum compounds: A new class of potent antitumour agents
-
B. Rosenberg, L. Van Camp, J.E. Trosko, V.H. Mansour. Platinum compounds: A new class of potent antitumour agents. Nature 222 (1969) 385e386.
-
(1969)
Nature
, vol.222
, pp. 385-386
-
-
Rosenberg, B.1
Van Camp, L.2
Trosko, J.E.3
Mansour, V.H.4
-
6
-
-
0041629528
-
Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma
-
N.J. Vogelzang, J.J. Rusthoven, J. Symanowski, C. Denham, E. Kaukel, P. Ruffie, U. Gatzemeier, M. Boyer, S. Emri, C. Manegold, C. Niyikiza, P. Paoletti. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J. Clin. Oncol. 21 (2003) 2636e2644.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2636-2644
-
-
Vogelzang, N.J.1
Rusthoven, J.J.2
Symanowski, J.3
Denham, C.4
Kaukel, E.5
Ruffie, P.6
Gatzemeier, U.7
Boyer, M.8
Emri, S.9
Manegold, C.10
Niyikiza, C.11
Paoletti, P.12
-
7
-
-
0141869677
-
Cisplatin nephrotoxicity
-
I.S. Arany, L. Robert. Cisplatin nephrotoxicity. Semin. Nephrol. 23 (2003) 460e464.
-
(2003)
Semin. Nephrol.
, vol.23
, pp. 460-464
-
-
Arany, I.S.1
Robert, L.2
-
8
-
-
0028815902
-
Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: A randomized double-blind placebo-controlled trial J
-
S.C. Cascinu, L.D. Ferro, E. Fronzoni, M. Catalano. Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: A randomized double-blind placebo-controlled trial, J. Clin. Oncol. 13 (1995) 26e32.
-
(1995)
Clin. Oncol.
, vol.13
, pp. 26-32
-
-
Cascinu, S.C.1
Ferro, L.D.2
Fronzoni, E.3
Catalano, M.4
-
10
-
-
0025816320
-
The relationships between glutathione, glutathione-S-Transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines
-
P. Mistry, L.R. Kelland, G. Abel, S. Sidhar, K.R. Harrap. The relationships between glutathione, glutathione-S-Transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines. Briti. J. Cancer 64 (1991) 215e220.
-
(1991)
Briti. J. Cancer
, vol.64
, pp. 215-220
-
-
Mistry, P.1
Kelland, L.R.2
Abel, G.3
Sidhar, S.4
Harrap, K.R.5
-
11
-
-
0026512446
-
A chronopharmacologic phase II clinical trial with 5-fluorouracil folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump High antitumor effectiveness against metastatic colorectal cancer
-
F. L-evi, J.L. Misset, S. Brienza, R. Adam, G. Metzger, M. Itzakhi, J.P. Caussanel, F. Kunstlinger, S. Lecouturier, A. Descorps-Decl-ere, A chronopharmacologic phase II clinical trial with 5-fluorouracil. folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. High antitumor effectiveness against metastatic colorectal cancer. Cancer 69 (1992) 893e900.
-
(1992)
Cancer
, vol.69
, pp. 893-900
-
-
L-Evi, F.1
Misset, J.L.2
Brienza, S.3
Adam, R.4
Metzger, G.5
Itzakhi, M.6
Caussanel, J.P.7
Kunstlinger, F.8
Lecouturier, S.9
Descorps-Decl-Ere, A.10
-
12
-
-
43049147578
-
New trends for metal complexes with anticancer activity
-
P.C.A. Bruijnincx, P.J. Sadler. New trends for metal complexes with anticancer activity. Curr. Opin. Chem. Biol. 12 (2008) 197e206.
-
(2008)
Curr. Opin. Chem. Biol.
, vol.12
, pp. 197-206
-
-
Bruijnincx, P.C.A.1
Sadler, P.J.2
-
13
-
-
79953313413
-
Targeting G-quadruplexes in gene promoters: A novel anticancer strategy
-
S. Balasubramanian, L.H. Hurlry, S. Neidle. Targeting G-quadruplexes in gene promoters: A novel anticancer strategy. Nat. Rev. Drug Discov. 10 (2011) 261e275.
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 261-275
-
-
Balasubramanian, S.1
Hurlry, L.H.2
Neidle, S.3
-
14
-
-
36949000648
-
Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes
-
S. Ray, R. Mohan, J.K. Singh, M.K. Samantaray, M.M. Shaikh, D. Panda, P. Ghosh. Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes. J. Am. Chem. Soc. 129 (2007) 15042e15053.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 15042-15053
-
-
Ray, S.1
Mohan, R.2
Singh, J.K.3
Samantaray, M.K.4
Shaikh, M.M.5
Panda, D.6
Ghosh, P.7
-
15
-
-
49649092606
-
New palladium(II) and platinum(II) complexes with 9-Aminoacridine: Structures, luminiscence, theoretical calculations, and antitumor activity
-
J. Ruiz, J. Lorenzo, C. Vicente, G. L-opez, J. María L-opez-de-Luzuriaga, M. Monge, F.X. Avil-es, D. Bautista, V. Moreno, A. Laguna. New palladium(II) and platinum( II) complexes with 9-Aminoacridine: Structures, luminiscence, theoretical calculations, and antitumor activity. Inorg. Chem. 47 (2008) 6990e7001.
-
(2008)
Inorg. Chem.
, vol.47
, pp. 6990-7001
-
-
Ruiz, J.1
Lorenzo, J.2
Vicente, C.3
L-Opez, G.4
María Lopez-De-Luzuriaga, J.5
Monge, M.6
Avil-Es, F.X.7
Bautista, D.8
Moreno, V.9
Laguna, A.10
-
16
-
-
75849129605
-
New pHdependent complexes, from mononuclear Pd(II) monomer to heteronuclear [Pd(II),K(I)] polymer: DNA cleavage and cytotoxicity in vitro
-
E.J. Gao, M.C. Zhu, Y. Huang, L. Liu, H.Y. Liu, F.C. Liu, S. Ma, C.Y. Shi. New pHdependent complexes, from mononuclear Pd(II) monomer to heteronuclear [Pd(II),K(I)] polymer: DNA cleavage and cytotoxicity in vitro. Eur. J. Med.Chem. 45 (2010) 1034e1041.
-
(2010)
Eur. J. Med.Chem.
, vol.45
, pp. 1034-1041
-
-
Gao, E.J.1
Zhu, M.C.2
Huang, Y.3
Liu, L.4
Liu, H.Y.5
Liu, F.C.6
Ma, S.7
Shi, C.Y.8
-
17
-
-
0028169195
-
Nicl-os-Guti-errez. Cis-Dichloro-palladium(II) complexes with diaminosuccinic acid and its diethyl ester: Syn thesis, molecular structure, and preliminary DNA-binding and antitumor studies
-
A. Matilla, J.M. Tercero, J. Nicl-os-Guti-errez. cis-Dichloro-palladium(II) complexes with diaminosuccinic acid and its diethyl ester: Synthesis, molecular structure, and preliminary DNA-binding and antitumor studies. J. Inorg. Biochem. 55 (1994) 235e247.
-
(1994)
J. Inorg. Biochem.
, vol.55
, pp. 235-247
-
-
Matilla, A.1
Tercero J, J.M.2
-
18
-
-
84655162025
-
Imidazo [4,5f] [1,10] phenanthroline derivatives as inhibitor of c-myc gene expression in A549 cells via NF-kappaB pathway
-
D.D. Sun, W.Z. Wang, J.V.V. Mao, W.J. Mei, J. Liu. Imidazo [4,5f] [1,10] phenanthroline derivatives as inhibitor of c-myc gene expression in A549 cells via NF-kappaB pathway. Bioorg. Med. Chem. Lett. 22 (2012) 102e105.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 102-105
-
-
Sun, D.D.1
Wang, W.Z.2
Mao, J.V.V.3
Mei, W.J.4
Liu, J.5
-
19
-
-
33845344313
-
Studies on the activity of three palladium( II) compounds of the form: Trans-PdL2Cl2 where L2-hydroxypyridine, 3-hydroxypyridine, and 4-hydroxy-pyridine
-
F. Huq, H. Tayyem, P. Beale, J.Q. Yu. Studies on the activity of three palladium( II) compounds of the form: Trans-PdL2Cl2 where L2-hydroxypyridine, 3-hydroxypyridine, and 4-hydroxy-pyridine. J. Inorg. Biochem. 101 (2007) 30e35.
-
(2007)
J. Inorg. Biochem.
, vol.101
, pp. 30-35
-
-
Huq, F.1
Tayyem, H.2
Beale, P.3
Yu, J.Q.4
-
20
-
-
34250213644
-
The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators
-
S. Kemp, N.J. Wheate, D.P. Buck, M. Nikac, J.G. Collins, J.R. Aldrich-Wright. The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators. J. Inorg. Biochem. 101 (2007) 1049e1058.
-
(2007)
J. Inorg. Biochem.
, vol.101
, pp. 1049-1058
-
-
Kemp, S.1
Wheate, N.J.2
Buck, D.P.3
Nikac, M.4
Collins, J.G.5
Aldrich-Wright, J.R.6
-
21
-
-
0022630529
-
Some potential anticancer palladium(II) complexes of 2,20-bipyridine and amino acids
-
K.H. Puthraya, T.S. Srivastava, A.J. Amonkar, M.K. Adwankar, M.P. Chitnis. Some potential anticancer palladium(II) complexes of 2,20-bipyridine and amino acids. J. Inorg. Biochem. 26 (1986) 45e54.
-
(1986)
J. Inorg. Biochem.
, vol.26
, pp. 45-54
-
-
Puthraya, K.H.1
Srivastava, T.S.2
Amonkar, A.J.3
Adwankar, M.K.4
Chitnis, M.P.5
-
22
-
-
0026028535
-
Syn thesis characterization DNA binding, and cytotoxic studies of some mixed-ligand palladium(II) and platinum(II) complexes of a-diimine and amino acids
-
R.S. Mital, T.S. Parekh, H.K. Chitnis. Synthesis, characterization, DNA binding, and cytotoxic studies of some mixed-ligand palladium(II) and platinum(II) complexes of a-diimine and amino acids. J. Inorg. Biochem. 41 (1991) 93e103.
-
(1991)
J. Inorg. Biochem.
, vol.41
, pp. 93-103
-
-
Mital, R.S.1
Parekh, T.S.2
Chitnis, H.K.3
-
23
-
-
79958739189
-
Synthesis and characterization of some potential antitumor palladium(II) complexes of 2-Aminomethylbenzimidazole and amino acids
-
A.A. El-Sherif. Synthesis and characterization of some potential antitumor palladium(II) complexes of 2-Aminomethylbenzimidazole and amino acids. J. Coord. Chem. 64 (2011) 2035e2055.
-
(2011)
J. Coord. Chem.
, vol.64
, pp. 2035-2055
-
-
El-Sherif, A.A.1
-
24
-
-
77957840485
-
Syn thesis, characterization and cytotoxicity of mixed-ligand complexes of palladium(II) with aromatic diimine and 4-Toluenesulfonyl-l-Amino acid dianion, Eur
-
J.C. Zhang, L.W. Li, L.W. Wang, F.F. Zhang, X.L. Li. Synthesis, characterization and cytotoxicity of mixed-ligand complexes of palladium(II) with aromatic diimine and 4-Toluenesulfonyl-l-Amino acid dianion, Eur. J. Med.Chem. 4 (2010) 5337e5344.
-
(2010)
J. Med.Chem.
, vol.4
, pp. 5337-5344
-
-
Zhang, J.C.1
Li, L.W.2
Wang, L.W.3
Zhang, F.F.4
Li, X.L.5
-
25
-
-
80054878534
-
Syn thesis characterization and cytotoxicity of mixed-ligand complexes of palladium(II) with 2, 20-biquinoline/1, 4-diaminobutane and 4-Toluenesulfonyl-L-Amino acid dianion
-
J.C. Zhang, L.W. Li, L.L. Ma, F.F. Zhang, Z.L. Zhang, S.X. Wang. Synthesis, characterization and cytotoxicity of mixed-ligand complexes of palladium(II) with 2, 20-biquinoline/1, 4-diaminobutane and 4-Toluenesulfonyl-L-Amino acid dianion. Eur. J. Med. Chem. 46 (2011) 5711e5716.
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 5711-5716
-
-
Zhang, J.C.1
Li, L.W.2
Ma, L.L.3
Zhang, F.F.4
Zhang, Z.L.5
Wang, S.X.6
-
26
-
-
84868235337
-
Syn thesis characterization and cytotoxicity of platinum(II)/palladium(II) complexes with 1,3-diaminopropane and 4-Toluensulfonyl-L-Amino acid dianion
-
J.C. Zhang, L.L. Ma, H.R. Lu, Y.C. Wang, S.H. Li, S.X. Wang, G.Q. Zhou. Synthesis, characterization and cytotoxicity of platinum(II)/palladium(II) complexes with 1,3-diaminopropane and 4-Toluensulfonyl-L-Amino acid dianion. Eur. J. Med.Chem. 58 (2012) 281e286.
-
(2012)
Eur. J. Med.Chem.
, vol.58
, pp. 281-286
-
-
Zhang, J.C.1
Ma, L.L.2
Lu, H.R.3
Wang, Y.C.4
Li, S.H.5
Wang, S.X.6
Zhou, G.Q.7
-
27
-
-
84863068271
-
Syn thesis characterization, and biological activity of five new mixed-ligand palladium( II) complexes with ethylenediamine and 4-Toluenesulfonyl-L-Amino acid dianion
-
J.C. Zhang, L.L. Ma, F.F. Zhang, Z.L. Zhang, L.W. Li, S.X. Wang. Synthesis, characterization, and biological activity of five new mixed-ligand palladium( II) complexes with ethylenediamine and 4-Toluenesulfonyl-L-Amino acid dianion. J. Coord. Chem. 65 (2012) 239e250.
-
(2012)
J. Coord. Chem.
, vol.65
, pp. 239-250
-
-
Zhang, J.C.1
Ma, L.L.2
Zhang, F.F.3
Zhang, Z.L.4
Li, L.W.5
Wang, S.X.6
-
28
-
-
84865005129
-
Syn thesis characterization, and cytotoxicity of complexes of palladium(II) with 1,4-diaminobutane/1,3-diaminopropane and 4-Toluenesulfonyl-L-Amino acid dianion
-
J.C. Zhang, L.L. Ma, F.F. Zhang, C. Chen, L.W. Li, S.X. Wang, S.H. Li. Synthesis, characterization, and cytotoxicity of complexes of palladium(II) with 1,4-diaminobutane/1,3-diaminopropane and 4-Toluenesulfonyl-L-Amino acid dianion. J. Coord. Chem. 65 (2012) 3160e3173.
-
(2012)
J. Coord. Chem.
, vol.65
, pp. 3160-3173
-
-
Zhang, J.C.1
Ma, L.L.2
Zhang, F.F.3
Chen, C.4
Li, L.W.5
Wang, S.X.6
Li, S.H.7
-
29
-
-
84861870940
-
Syn thesis characterization, and cytotoxicity of complexes of platinum(II) with 2,20-bipyridine and N-benzoyl-L-Amino acid dianion
-
J.C. Zhang, F.F. Zhang, L.W. Wang, J.L. Du, S.X. Wang, S.H. Li. Synthesis, characterization, and cytotoxicity of complexes of platinum(II) with 2,20-bipyridine and N-benzoyl-L-Amino acid dianion. J. Coord. Chem. 65 (2012) 2159e2169.
-
(2012)
J. Coord. Chem.
, vol.65
, pp. 2159-2169
-
-
Zhang, J.C.1
Zhang, F.F.2
Wang, L.W.3
Du, J.L.4
Wang, S.X.5
Li, S.H.6
-
30
-
-
79960510738
-
Rational design of zinceorganic coordination polymers directed by n-donor co-ligands
-
S.J. Wang, S.S. Wang, Z.Y. Wang, J.F. Du. Rational design of zinceorganic coordination polymers directed by n-donor co-ligands. Chem. Eur. J. 17 (2012) 8630e8642.
-
(2012)
Chem. Eur. J.
, vol.17
, pp. 8630-8642
-
-
Wang, S.J.1
Wang, S.S.2
Wang, Z.Y.3
Du, J.F.4
-
31
-
-
51849142264
-
Palladium polypyridyl complexes: Syn thesis characterization DNA interaction and biological activity on Leishmania L) mexicana
-
M.B. Navarro, H. Adelmo, M. Clara. Palladium polypyridyl complexes: Synthesis, characterization, DNA interaction and biological activity on Leishmania (L.) mexicana. J. Braz. Chem. Soc. 19 (2008) 1355e1360.
-
(2008)
J. Braz. Chem. Soc.
, vol.19
, pp. 1355-1360
-
-
Navarro, M.B.1
Adelmo, H.2
Clara, M.3
-
32
-
-
0000528608
-
A 1H NMR study of the DNA binding of Ruthenium(II) polypyridyl complexes
-
J.G. Collins, R. Janice, W. Aldrich, G. Ivan, T.W. Hambley, A 1H NMR study of the DNA binding of Ruthenium(II) polypyridyl complexes. Inorg. Chem. 37 (1998) 3133e3141.
-
(1998)
Inorg. Chem.
, vol.37
, pp. 3133-3141
-
-
Collins, J.G.1
Janice, R.2
Aldrich, W.3
Ivan, G.4
Hambley, T.W.5
-
33
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
T. Mosmann. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55e63.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
|