Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice

Hepatology

Volumn 63, Issue 3, 2016, Pages 914-929

  Zhou, Mei ^a   Learned, R Marc ^a   Rossi, Stephen J ^a   Depaoli, Alex M ^a   Tian, Hui ^a   Ling, Lei ^a  

^a NGM Biopharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL 7ALPHA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR 19; HORMONE ANALOG; M70; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15, MOUSE;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BILE ACID BLOOD LEVEL; BILE ACID SYNTHESIS; BILE DUCT DISEASE; BILIARY TRACT FIBROSIS; CHOLELITHIASIS; FEMALE; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC VARIABILITY; HEPATITIS; HEPATOSPLENOMEGALY; LIVER CELL CARCINOMA; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCLEROSING CHOLANGITIS; VIRAL GENE THERAPY; AMINO ACID SEQUENCE; ANIMAL; CARCINOMA, HEPATOCELLULAR; CHOLANGITIS, SCLEROSING; CHOLECYSTOLITHIASIS; DISEASE MODEL; EVALUATION STUDY; GENE THERAPY; GENETICS; HOMEOSTASIS; LIPID METABOLISM; LIVER NEOPLASMS; METABOLISM; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANIMALS; BILE ACIDS AND SALTS; CARCINOMA, HEPATOCELLULAR; CHOLANGITIS, SCLEROSING; CHOLECYSTOLITHIASIS; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLAST GROWTH FACTORS; GENETIC THERAPY; HOMEOSTASIS; LIPID METABOLISM; LIVER NEOPLASMS; MALE; MICE; MOLECULAR SEQUENCE DATA;

EID: 84949884025     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28257     Document Type: Article

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