Microglial inhibitory mechanism of coenzyme Q10 against Aβ (1-42) induced cognitive dysfunctions: Possible behavioral, biochemical, cellular, and histopathological alterations

Frontiers in Pharmacology

Volumn 6, Issue NOV, 2015, Pages

  Singh, Arti ^a   Kumar, Anil ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Alzheimer's disease; A (1 42); Coenzyme Q10; Minocycline; Mitochondrial dysfunction; Neuroinflammation; Oxidative stress

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN[1-42]; CATALASE; GLUTATHIONE; MINOCYCLINE; MITOCHONDRIAL ENZYME; MITOCHONDRIAL RESPIRATORY ENZYME COMPLEX I; MITOCHONDRIAL RESPIRATORY ENZYME COMPLEX II; MITOCHONDRIAL RESPIRATORY ENZYME COMPLEX III; MITOCHONDRIAL RESPIRATORY ENZYME COMPLEX IV; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA; UBIDECARENONE; UNCLASSIFIED DRUG;

ADULT; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; COGNITIVE DEFECT; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; HIPPOCAMPUS; HISTOPATHOLOGY; LATENT PERIOD; LIPID PEROXIDATION; MALE; MICROGLIAL INHIBITORY MECHANISM; MONOTHERAPY; MORRIS WATER MAZE TEST; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; TREATMENT DURATION;

EID: 84949752761     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00268     Document Type: Article

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