Microrna and wound healing

Advances in Experimental Medicine and Biology

Volumn 888, Issue , 2015, Pages 291-305

  Banerjee, Jaideep ^a   Sen, Chandan K ^b  

^a US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Angiogenesis; HypoxymiRs; Inflammation; Re epithelialization; Wound healing

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FIBROBLAST GROWTH FACTOR 2; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR; INTERCELLULAR ADHESION MOLECULE 1; LIPOSOME; LOCKED NUCLEIC ACID; MEMBRANE PROTEIN; MICRORNA; MICRORNA 17 3P; MICRORNA 31; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 4 RECEPTOR; SILICA NANOPARTICLE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

3' UNTRANSLATED REGION; ANGIOGENESIS; ANTIBODY SPECIFICITY; BIODEGRADABILITY; BIOGENESIS; CELL SURVIVAL; COST EFFECTIVENESS ANALYSIS; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG CONJUGATION; ECONOMIC ASPECT; ENDOCYTOSIS; EPITHELIZATION; GENE EXPRESSION PROFILING; GENE REPRESSION; GENE SILENCING; HUMAN; HYDROLYSIS; IMMUNE RESPONSE; IMMUNOGENICITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OXYGENATION; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STABILITY; RENAL CLEARANCE; RNA DEGRADATION; TISSUE OXYGENATION; TRANSCRIPTION REGULATION; WOUND CLOSURE; WOUND HEALING; ANIMAL; ANOXIA; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN; SKIN DISEASE; VASCULARIZATION;

ANIMALS; ANOXIA; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICRORNAS; MODELS, GENETIC; NEOVASCULARIZATION, PHYSIOLOGIC; RE-EPITHELIALIZATION; SKIN; SKIN DISEASES; WOUND HEALING;

EID: 84949680846     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-22671-2_15     Document Type: Chapter

References (68)

1. Gottrup F. A specialized wound-healing center concept: importance of a multidisciplinary department structure and surgical treatment facilities in the treatment of chronic wounds. Am J Surg. 2004;187(5A):38S-43
2. Sen CK, et al. Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen. 2009;17(6):763-71
3. Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2): 215-33
4. Tay Y, et al. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature. 2008;455(7216):1124-8
5. Orom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell. 2008;30(4):460-71
6. Ravishankar D. Global analysis of microRNA tools and services market: evolving microRNA market provides an opportunity for vendors of qRT-PCR and functional tools. Frost & Sullivan Research Service. Sep 2003
7. Analysis of microRNA tools and services market in Europe: microRNA research triggers tremendous growth in tools market. Frost & Sullivan Research Service. Feb 2012
8. Sen CK, Roy S. OxymiRs in cutaneous development, wound repair and regeneration. Semin Cell Dev Biol. 2012;23(9):971-80
9. Loscalzo J. The cellular response to hypoxia: tuning the system with microRNAs. J Clin Invest. 2010;120(11):3815-7
10. Cascio S, et al. miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells. J Cell Physiol. 2010;224(1):242-9
11. Rane S, et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res. 2009;104(7):879-86
12. Kulshreshtha R, et al. A microRNA component of the hypoxic response. Cell Death Differ. 2008;15(4):667-71
13. Taganov KD, et al. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A. 2006; 103(33):12481-6
14. Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol. 2004;4(7):499-511
15. Martinez-Nunez RT, et al. MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). J Biol Chem. 2009;284(24):16334-42
16. O’Connell RM, et al. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci U S A. 2009;106(17):7113-8
17. Tili E, Croce CM, Michaille JJ. miR-155: on the crosstalk between inflammation and cancer. Int Rev Immunol. 2009;28(5):264-84
18. Tili E, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol. 2007;179(8):5082-9
19. Suarez Y, et al. Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol. 2010;184(1):21-5
20. Roy S, et al. Characterization of the acute temporal changes in excisional murine cutaneous wound inflammation by screening of the wound-edge transcriptome. Physiol Genomics. 2008;34(2):162-84
21. Nakamachi Y, et al. MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 2009;60(5):1294-304
22. Recchiuti A, et al. MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits. FASEB J. 2011;25(2):544-60
23. Das A, et al. Engulfment of apoptotic cells by macrophages: a role of microRNA-21 in the resolution of wound inflammation. J Immunol. 2014;192(3):1120-9
24. Aragones J, et al. Oxygen sensors at the crossroad of metabolism. Cell Metab. 2009;9(1): 11-22
25. Boutilier RG, St-Pierre J. Surviving hypoxia without really dying. Comp Biochem Physiol A Mol Integr Physiol. 2000;126(4):481-90
26. Ho JJ, et al. Functional importance of Dicer protein in the adaptive cellular response to hypoxia. J Biol Chem. 2012;287(34):29003-20
27. Ghatak S, Chan YC, Khanna S, Banerjee J, Weist J, Roy S, Sen CK. Barrier function of the repaired skin is disrupted following arrest of Dicer in keratinocytes. Mol Ther. 2015;23(7): 1201-10
28. Wu C, et al. Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2. Mol Cell Biol. 2011;31(23):4760-74
29. Sen CK. Wound healing essentials: let there be oxygen. Wound Repair Regen. 2009;17(1): 1-18
30. Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev. 1979;59(3):527-605
31. Shigenaga MK, Hagen TM, Ames BN. Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci U S A. 1994;91(23):10771-8
32. Clark IA, Cowden WB, Hunt NH. Free radical-induced pathology. Med Res Rev. 1985;5(3):297-332
33. Dormandy TL. Free-radical pathology and medicine. A review. J R Coll Physicians Lond. 1989;23(4):221-7
34. Slater TF. Free-radical mechanisms in tissue injury. Biochem J. 1984;222(1):1-15
35. Sen CK, Packer L. Antioxidant and redox regulation of gene transcription. FASEB J. 1996; 10(7):709-20
36. Sen CK. Redox signaling and the emerging therapeutic potential of thiol antioxidants. Biochem Pharmacol. 1998;55(11):1747-58
37. Sen CK. Cellular thiols and redox-regulated signal transduction. Curr Top Cell Regul. 2000;36:1-30
38. Chen L, Endler A, Shibasaki F. Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors. Exp Mol Med. 2009;41(12):849-57
39. Sarkar K, et al. Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells. Cardiovasc Res. 2012;93(1):162-9
40. Giannakakis A, et al. miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer. Cancer Biol Ther. 2008;7(2):255-64
41. Huang X, et al. Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Mol Cell. 2009;35(6):856-67
42. Chan SY, et al. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab. 2009;10(4):273-84
43. Hunt TK, et al. Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms. Antioxid Redox Signal. 2007;9(8):1115-24
44. Loffler M, et al. Wound fluid lactate concentration: a helpful marker for diagnosing soft-tissue infection in diabetic foot ulcers? Preliminary findings. Diabet Med. 2011;28(2):175-8
45. Hashimoto T, et al. Lactate sensitive transcription factor network in L6 cells: activation of MCT1 and mitochondrial biogenesis. FASEB J. 2007;21(10):2602-12
46. Lu H, Forbes RA, Verma A. Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J Biol Chem. 2002;277(26):23111-5
47. Sen CK, et al. Oxidant-induced vascular endothelial growth factor expression in human keratinocytes and cutaneous wound healing. J Biol Chem. 2002;277(36):33284-90
48. Wang J, et al. c-Met upregulates aquaporin 3 expression in human gastric carcinoma cells via the ERK signalling pathway. Cancer Lett. 2012;319(1):109-17
49. Levin MH, Verkman AS. Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization. Invest Ophthalmol Vis Sci. 2006;47(10):4365-72
50. Elia L, et al. Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation. 2009;120(23):2377-85
51. Haase I, et al. Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. J Cell Sci. 2003;116(Pt 15):3227-38
52. Shilo S, et al. Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells. Arterioscler Thromb Vasc Biol. 2008;28(3):471-7
53. Kuehbacher A, et al. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res. 2007;101(1):59-68
54. Suarez Y, et al. Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ Res. 2007;100(8):1164-73
55. Caporali A, Emanueli C. MicroRNA regulation in angiogenesis. Vascul Pharmacol. 2011;55(4):79-86
56. Sen CK, et al. Oxygen, oxidants, and antioxidants in wound healing: an emerging paradigm. Ann N Y Acad Sci. 2002;957:239-49
57. Chan YC, et al. miR-200b targets Ets-1 and is down-regulated by hypoxia to induce angiogenic response of endothelial cells. J Biol Chem. 2011;286(3):2047-56
58. Suarez Y, et al. Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci U S A. 2008;105(37):14082-7
59. Chen Y, Gorski DH. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood. 2008;111(3):1217-26
60. Anand S, et al. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med. 2010;16(8):909-14
61. Poliseno L, et al. MicroRNAs modulate the angiogenic properties of HUVECs. Blood. 2006;108(9):3068-71
62. Litz J, Krystal GW. Imatinib inhibits c-Kit-induced hypoxia-inducible factor-1alpha activity and vascular endothelial growth factor expression in small cell lung cancer cells. Mol Cancer Ther. 2006;5(6):1415-22
63. Levin AA. A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim Biophys Acta. 1999;1489(1):69-84
64. Geary RS, Yu RZ, Levin AA. Pharmacokinetics of phosphorothioate antisense oligodeoxynucleotides. Curr Opin Investig Drugs. 2001;2(4):562-73
65. Ben-Shushan D, et al. Overcoming obstacles in microRNA delivery towards improved cancer therapy. Drug Deliv Transl Res. 2014;4(1):38-49
66. Gilleron J, et al. Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape. Nat Biotechnol. 2013;31(7):638-46
67. Henry JC, Azevedo-Pouly AC, Schmittgen TD. MicroRNA replacement therapy for cancer. Pharm Res. 2011;28(12):3030-42
68. Weiler J, Hunziker J, Hall J. Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? Gene Ther. 2006;13(6):496-502