-
1
-
-
0029051439
-
Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang, G. L., Jiang, B. H., Rue, E. A., and Semenza, G. L. (1995) Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. U.S.A. 92, 5510-5514
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
2
-
-
80051625243
-
Oxygen sensing, homeostasis, and disease
-
Semenza, G. L. (2011) Oxygen sensing, homeostasis, and disease. N. Engl. J. Med. 365, 537-547
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 537-547
-
-
Semenza, G.L.1
-
3
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza, G. L. (2012) Hypoxia-inducible factors in physiology and medicine. Cell 148, 399-408
-
(2012)
Cell
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
4
-
-
84862530396
-
Nitric oxide signaling in hypoxia
-
Ho, J. J., Man, H. S., and Marsden, P. A. (2012) Nitric oxide signaling in hypoxia. J. Mol. Med. 90, 217-231
-
(2012)
J. Mol. Med.
, vol.90
, pp. 217-231
-
-
Ho, J.J.1
Man, H.S.2
Marsden, P.A.3
-
5
-
-
0027938194
-
Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
-
McQuillan, L. P., Leung, G. K., Marsden, P. A., Kostyk, S. K., and Kourembanas, S. (1994) Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. Heart Circ. Physiol. 267, H1921-H1927
-
(1994)
Am. J. Physiol. Heart Circ. Physiol.
, vol.267
-
-
McQuillan, L.P.1
Leung, G.K.2
Marsden, P.A.3
Kostyk, S.K.4
Kourembanas, S.5
-
6
-
-
0032891180
-
Endothelial cell responses to hypoxic stress
-
Faller, D. V. (1999) Endothelial cell responses to hypoxic stress. Clin. Exp. Pharmacol. Physiol. 26, 74-84
-
(1999)
Clin. Exp. Pharmacol. Physiol.
, vol.26
, pp. 74-84
-
-
Faller, D.V.1
-
7
-
-
34447543034
-
Hypoxia-inducible expression of a natural cis-antisense transcript inhibits endothelial nitric-oxide synthase
-
DOI 10.1074/jbc.M608318200
-
Fish, J. E., Matouk, C. C., Yeboah, E., Bevan, S. C., Khan, M., Patil, K., Ohh, M., and Marsden, P. A. (2007) Hypoxia-inducible expression of a natural cis-antisense transcript inhibits endothelial nitric-oxide synthase. J. Biol. Chem. 282, 15652-15666 (Pubitemid 47093264)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.21
, pp. 15652-15666
-
-
Fish, J.E.1
Matouk, C.C.2
Yeboah, E.3
Bevan, S.C.4
Khan, M.5
Patil, K.6
Ohh, M.7
Marsden, P.A.8
-
8
-
-
47049119934
-
MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3
-
Fasanaro, P., D'Alessandra, Y., Di Stefano, V., Melchionna, R., Romani, S., Pompilio, G., Capogrossi, M. C., and Martelli, F. (2008) MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J. Biol. Chem. 283, 15878-15883
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15878-15883
-
-
Fasanaro, P.1
D'Alessandra, Y.2
Di Stefano, V.3
Melchionna, R.4
Romani, S.5
Pompilio, G.6
Capogrossi, M.C.7
Martelli, F.8
-
9
-
-
58849112575
-
Biogenesis of small RNAs in animals
-
Kim, V. N., Han, J., and Siomi, M. C. (2009) Biogenesis of small RNAs in animals. Nat. Rev. Mol. Cell Biol. 10, 126-139
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 126-139
-
-
Kim, V.N.1
Han, J.2
Siomi, M.C.3
-
10
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
DOI 10.1038/nature03868
-
Chendrimada, T. P., Gregory, R. I., Kumaraswamy, E., Norman, J., Cooch, N., Nishikura, K., and Shiekhattar, R. (2005) TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436, 740-744 (Pubitemid 41117280)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
Norman, J.4
Cooch, N.5
Nishikura, K.6
Shiekhattar, R.7
-
11
-
-
77950843538
-
The dicey role of Dicer: Implications for RNAi therapy
-
Merritt, W. M., Bar-Eli, M., and Sood, A. K. (2010) The dicey role of Dicer: implications for RNAi therapy. Cancer Res. 70, 2571-2574
-
(2010)
Cancer Res.
, vol.70
, pp. 2571-2574
-
-
Merritt, W.M.1
Bar-Eli, M.2
Sood, A.K.3
-
12
-
-
39749116239
-
Hypoxia and regulation of messenger RNA translation
-
Koritzinsky, M., and Wouters, B. G. (2007) Hypoxia and regulation of messenger RNA translation. Methods Enzymol. 435, 247-273
-
(2007)
Methods Enzymol.
, vol.435
, pp. 247-273
-
-
Koritzinsky, M.1
Wouters, B.G.2
-
13
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek, D., Villén, J., Shin, C., Camargo, F. D., Gygi, S. P., and Bartel, D. P. (2008) The impact of microRNAs on protein output. Nature 455, 64-71
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villén, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
14
-
-
2342597973
-
Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth
-
Kondo, K., Kim, W. Y., Lechpammer, M., and Kaelin, W. G., Jr. (2003) Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth. PLoS Biol. 1, E83
-
(2003)
PLoS Biol.
, vol.1
-
-
Kondo, K.1
Kim, W.Y.2
Lechpammer, M.3
Kaelin Jr., W.G.4
-
15
-
-
34247554263
-
Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells
-
Suárez, Y., Fernández-Hernando, C., Pober, J. S., and Sessa, W. C. (2007) Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ. Res. 100, 1164-1173
-
(2007)
Circ. Res.
, vol.100
, pp. 1164-1173
-
-
Suárez, Y.1
Fernández-Hernando, C.2
Pober, J.S.3
Sessa, W.C.4
-
16
-
-
1542305649
-
Role of the 3′-untranslated region of human endothelin-1 in vascular endothelial cells: Contribution to transcript lability and the cellular heat shock response
-
DOI 10.1074/jbc.M312190200
-
Mawji, I. A., Robb, G. B., Tai, S. C., and Marsden, P. A. (2004) Role of the 3′-untranslated region of human endothelin-1 in vascular endothelial cells. Contribution to transcript lability and the cellular heat shock response. J. Biol. Chem. 279, 8655-8667 (Pubitemid 38295921)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.10
, pp. 8655-8667
-
-
Mawji, I.A.1
Robb, G.B.2
Tai, S.C.3
Marsden, P.A.4
-
17
-
-
15544363403
-
Specific and potent RNAi in the nucleus of human cells
-
Robb, G. B., Brown, K. M., Khurana, J., and Rana, T. M. (2005) Specific and potent RNAi in the nucleus of human cells. Nat. Struct. Mol. Biol. 12, 133-137
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 133-137
-
-
Robb, G.B.1
Brown, K.M.2
Khurana, J.3
Rana, T.M.4
-
18
-
-
77951232952
-
Enhanced translation of heme oxygenase-2 preserves human endothelial cell viability during hypoxia
-
He, J. Z., Ho, J. J., Gingerich, S., Courtman, D. W., Marsden, P. A., and Ward, M. E. (2010) Enhanced translation of heme oxygenase-2 preserves human endothelial cell viability during hypoxia. J. Biol. Chem. 285, 9452-9461
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9452-9461
-
-
He, J.Z.1
Ho, J.J.2
Gingerich, S.3
Courtman, D.W.4
Marsden, P.A.5
Ward, M.E.6
-
19
-
-
52949143124
-
Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response
-
Koeman, J. M., Russell, R. C., Tan, M. H., Petillo, D., Westphal, M., Koelzer, K., Metcalf, J. L., Zhang, Z., Matsuda, D., Dykema, K. J., Houseman, H. L., Kort, E. J., Furge, L. L., Kahnoski, R. J., Richard, S., Vieillefond, A., Swiatek, P. J., Teh, B. T., Ohh, M., and Furge, K. A. (2008) Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response. PLoS Genet. 4, e1000176
-
(2008)
PLoS Genet.
, vol.4
-
-
Koeman, J.M.1
Russell, R.C.2
Tan, M.H.3
Petillo, D.4
Westphal, M.5
Koelzer, K.6
Metcalf, J.L.7
Zhang, Z.8
Matsuda, D.9
Dykema, K.J.10
Houseman, H.L.11
Kort, E.J.12
Furge, L.L.13
Kahnoski, R.J.14
Richard, S.15
Vieillefond, A.16
Swiatek, P.J.17
Teh, B.T.18
Ohh, M.19
Furge, K.A.20
more..
-
20
-
-
71749100911
-
An integrated approach for experimental target identification of hypoxia-induced miR-210
-
Fasanaro, P., Greco, S., Lorenzi, M., Pescatori, M., Brioschi, M., Kulshreshtha, R., Banfi, C., Stubbs, A., Calin, G. A., Ivan, M., Capogrossi, M. C., and Martelli, F. (2009) An integrated approach for experimental target identification of hypoxia-induced miR-210. J. Biol. Chem. 284, 35134-35143
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35134-35143
-
-
Fasanaro, P.1
Greco, S.2
Lorenzi, M.3
Pescatori, M.4
Brioschi, M.5
Kulshreshtha, R.6
Banfi, C.7
Stubbs, A.8
Calin, G.A.9
Ivan, M.10
Capogrossi, M.C.11
Martelli, F.12
-
21
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
DOI 10.1038/nature04791, PII NATURE04791
-
Grimm, D., Streetz, K. L., Jopling, C. L., Storm, T. A., Pandey, K., Davis, C. R., Marion, P., Salazar, F., and Kay, M. A. (2006) Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441, 537-541 (Pubitemid 44050158)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
22
-
-
0029758798
-
Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia
-
Waltenberger, J., Mayr, U., Pentz, S., and Hombach, V. (1996) Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia. Circulation 94, 1647-1654 (Pubitemid 26320271)
-
(1996)
Circulation
, vol.94
, Issue.7
, pp. 1647-1654
-
-
Waltenberger, J.1
Mayr, U.2
Pentz, S.3
Hombach, V.4
-
23
-
-
0030751493
-
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
-
DOI 10.1074/jbc.272.38.23659
-
Gerber, H. P., Condorelli, F., Park, J., and Ferrara, N. (1997) Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J. Biol. Chem. 272, 23659-23667 (Pubitemid 27410939)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.38
, pp. 23659-23667
-
-
Gerber, H.-P.1
Condorelli, F.2
Park, J.3
Ferrara, N.4
-
24
-
-
3343013829
-
Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1
-
DOI 10.1161/01.RES.0000134920.10128.b4
-
Takeda, N., Maemura, K., Imai, Y., Harada, T., Kawanami, D., Nojiri, T., Manabe, I., and Nagai, R. (2004) Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1. Circ. Res. 95, 146-153 (Pubitemid 38988680)
-
(2004)
Circulation Research
, vol.95
, Issue.2
, pp. 146-153
-
-
Takeda, N.1
Maemura, K.2
Imai, Y.3
Harada, T.4
Kawanami, D.5
Nojiri, T.6
Manabe, I.7
Nagai, R.8
-
25
-
-
77952616432
-
Adaptation to oxygen deprivation in cultures of human pluripotent stem cells, endothelial progenitor cells, and umbilical vein endothelial cells
-
Abaci, H. E., Truitt, R., Luong, E., Drazer, G., and Gerecht, S. (2010) Adaptation to oxygen deprivation in cultures of human pluripotent stem cells, endothelial progenitor cells, and umbilical vein endothelial cells. Am. J. Physiol. Cell Physiol. 298, C1527-C1537
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
-
-
Abaci, H.E.1
Truitt, R.2
Luong, E.3
Drazer, G.4
Gerecht, S.5
-
26
-
-
27644499187
-
Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant
-
DOI 10.1172/JCI20806
-
Ward, M. E., Toporsian, M., Scott, J. A., Teoh, H., Govindaraju, V., Quan, A., Wener, A. D., Wang, G., Bevan, S. C., Newton, D. C., and Marsden, P. A. (2005) Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant. J. Clin. Investig. 115, 3128-3139 (Pubitemid 41567577)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.11
, pp. 3128-3139
-
-
Ward, M.E.1
Toporsian, M.2
Scott, J.A.3
Teoh, H.4
Govindaraju, V.5
Quan, A.6
Wener, A.D.7
Wang, G.8
Bevan, S.C.9
Newton, D.C.10
Marsden, P.A.11
-
27
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman, R. C., Farh, K. K., Burge, C. B., and Bartel, D. P. (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19, 92-105
-
(2009)
Genome Res.
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
28
-
-
53049103702
-
Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner
-
Purpura, K. A., George, S. H., Dang, S. M., Choi, K., Nagy, A., and Zandstra, P. W. (2008) Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells 26, 2832-2842
-
(2008)
Stem Cells
, vol.26
, pp. 2832-2842
-
-
Purpura, K.A.1
George, S.H.2
Dang, S.M.3
Choi, K.4
Nagy, A.5
Zandstra, P.W.6
-
29
-
-
80052838800
-
Hypoxia-inducible factor-1α mRNA: A new target for destabilization by tristetraprolin in endothelial cells
-
Chamboredon, S., Ciais, D., Desroches-Castan, A., Savi, P., Bono, F., Feige, J. J., and Cherradi, N. (2011) Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells. Mol. Biol. Cell 22, 3366-3378
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 3366-3378
-
-
Chamboredon, S.1
Ciais, D.2
Desroches-Castan, A.3
Savi, P.4
Bono, F.5
Feige, J.J.6
Cherradi, N.7
-
30
-
-
10744219598
-
Regulation of the Chemokine Receptor CXCR4 by Hypoxia
-
DOI 10.1084/jem.20030267
-
Schioppa, T., Uranchimeg, B., Saccani, A., Biswas, S. K., Doni, A., Rapisarda, A., Bernasconi, S., Saccani, S., Nebuloni, M., Vago, L., Mantovani, A., Melillo, G., and Sica, A. (2003) Regulation of the chemokine receptor CXCR4 by hypoxia. J. Exp. Med. 198, 1391-1402 (Pubitemid 37392484)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.9
, pp. 1391-1402
-
-
Schioppa, T.1
Uranchimeg, B.2
Saccani, A.3
Biswas, S.K.4
Doni, A.5
Rapisarda, A.6
Bernasconi, S.7
Saccani, S.8
Nebuloni, M.9
Vago, L.10
Mantovani, A.11
Melillo, G.12
Sica, A.13
-
31
-
-
84862778053
-
Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish
-
Bazzini, A. A., Lee, M. T., and Giraldez, A. J. (2012) Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish. Science 336, 233-237
-
(2012)
Science
, vol.336
, pp. 233-237
-
-
Bazzini, A.A.1
Lee, M.T.2
Giraldez, A.J.3
-
32
-
-
84859632747
-
MiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay
-
Djuranovic, S., Nahvi, A., and Green, R. (2012) miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science 336, 237-240
-
(2012)
Science
, vol.336
, pp. 237-240
-
-
Djuranovic, S.1
Nahvi, A.2
Green, R.3
-
33
-
-
80055061481
-
MicroRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4
-
Tano, N., Kim, H. W., and Ashraf, M. (2011) microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4. PLoS One 6, e23114
-
(2011)
PLoS One
, vol.6
-
-
Tano, N.1
Kim, H.W.2
Ashraf, M.3
-
34
-
-
37849026049
-
Double-stranded RNA-binding protein regulates vascular endothelial growth factor mRNA stability, translation, and breast cancer angiogenesis
-
Vumbaca, F., Phoenix, K. N., Rodriguez-Pinto, D., Han, D. K., and Claffey, K. P. (2008) Double-stranded RNA-binding protein regulates vascular endothelial growth factor mRNA stability, translation, and breast cancer angiogenesis. Mol. Cell. Biol. 28, 772-783
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 772-783
-
-
Vumbaca, F.1
Phoenix, K.N.2
Rodriguez-Pinto, D.3
Han, D.K.4
Claffey, K.P.5
-
35
-
-
54949154476
-
MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
-
Hua, Z., Lv, Q., Ye, W., Wong, C. K., Cai, G., Gu, D., Ji, Y., Zhao, C., Wang, J., Yang, B. B., and Zhang, Y. (2006) MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One 1, e116
-
(2006)
PLoS One
, vol.1
-
-
Hua, Z.1
Lv, Q.2
Ye, W.3
Wong, C.K.4
Cai, G.5
Gu, D.6
Ji, Y.7
Zhao, C.8
Wang, J.9
Yang, B.B.10
Zhang, Y.11
-
36
-
-
77950799838
-
MicroRNA-519c suppresses hypoxia-inducible factor-1α expression and tumor angiogenesis
-
Cha, S. T., Chen, P. S., Johansson, G., Chu, C. Y., Wang, M. Y., Jeng, Y. M., Yu, S. L., Chen, J. S., Chang, K. J., Jee, S. H., Tan, C. T., Lin, M. T., and Kuo, M. L. (2010) MicroRNA-519c suppresses hypoxia-inducible factor-1α expression and tumor angiogenesis. Cancer Res. 70, 2675-2685
-
(2010)
Cancer Res.
, vol.70
, pp. 2675-2685
-
-
Cha, S.T.1
Chen, P.S.2
Johansson, G.3
Chu, C.Y.4
Wang, M.Y.5
Jeng, Y.M.6
Yu, S.L.7
Chen, J.S.8
Chang, K.J.9
Jee, S.H.10
Tan, C.T.11
Lin, M.T.12
Kuo, M.L.13
-
37
-
-
78049424494
-
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
-
Ghosh, G., Subramanian, I. V., Adhikari, N., Zhang, X., Joshi, H. P., Basi, D., Chandrashekhar, Y. S., Hall, J. L., Roy, S., Zeng, Y., and Ramakrishnan, S. (2010) Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J. Clin. Investig. 120, 4141-4154
-
(2010)
J. Clin. Investig.
, vol.120
, pp. 4141-4154
-
-
Ghosh, G.1
Subramanian, I.V.2
Adhikari, N.3
Zhang, X.4
Joshi, H.P.5
Basi, D.6
Chandrashekhar, Y.S.7
Hall, J.L.8
Roy, S.9
Zeng, Y.10
Ramakrishnan, S.11
-
38
-
-
77950905821
-
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
-
Yamakuchi, M., Lotterman, C. D., Bao, C., Hruban, R. H., Karim, B., Mendell, J. T., Huso, D., and Lowenstein, C. J. (2010) p53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 107, 6334-6339
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 6334-6339
-
-
Yamakuchi, M.1
Lotterman, C.D.2
Bao, C.3
Hruban, R.H.4
Karim, B.5
Mendell, J.T.6
Huso, D.7
Lowenstein, C.J.8
-
39
-
-
2442544693
-
Prolonged hypoxia differentially regulates hypox-ia- inducible factor (HIF)-1α and HIF-2α expression in lung epithelial cells: Implication of natural antisense HIF-1α
-
Uchida, T., Rossignol, F., Matthay, M. A., Mounier, R., Couette, S., Clottes, E., and Clerici, C. (2004) Prolonged hypoxia differentially regulates hypox-ia- inducible factor (HIF)-1α and HIF-2α expression in lung epithelial cells: implication of natural antisense HIF-1α. J. Biol. Chem. 279, 14871-14878
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14871-14878
-
-
Uchida, T.1
Rossignol, F.2
Matthay, M.A.3
Mounier, R.4
Couette, S.5
Clottes, E.6
Clerici, C.7
-
40
-
-
70350217762
-
HIF-1α versus HIF-2α in endothelial cells and vascular functions: Is there a master in angiogenesis regulation?
-
Skuli, N., and Simon, M. C. (2009) HIF-1α versus HIF-2α in endothelial cells and vascular functions: is there a master in angiogenesis regulation? Cell Cycle 8, 3252-3253
-
(2009)
Cell Cycle
, vol.8
, pp. 3252-3253
-
-
Skuli, N.1
Simon, M.C.2
-
41
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
DOI 10.1128/MCB.25.13.5675-5686.2005
-
Raval, R. R., Lau, K. W., Tran, M. G., Sowter, H. M., Mandriota, S. J., Li, J. L., Pugh, C. W., Maxwell, P. H., Harris, A. L., and Ratcliffe, P. J. (2005) Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol. Cell. Biol. 25, 5675-5686 (Pubitemid 40853601)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.B.3
Sowter, H.M.4
Mandriota, S.J.5
Li, J.-L.6
Pugh, C.W.7
Maxwell, P.H.8
Harris, A.L.9
Ratcliffe, P.J.10
-
42
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
DOI 10.1038/nbt1051
-
Kim, D. H., Behlke, M. A., Rose, S. D., Chang, M. S., Choi, S., and Rossi, J. J. (2005) Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat. Biotechnol. 23, 222-226 (Pubitemid 40255333)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.2
, pp. 222-226
-
-
Kim, D.-H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.-S.4
Choi, S.5
Rossi, J.J.6
-
43
-
-
83255192187
-
Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2
-
Wu, C., So, J., Davis-Dusenbery, B. N., Qi, H. H., Bloch, D. B., Shi, Y., Lagna, G., and Hata, A. (2011) Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2. Mol. Cell. Biol. 31, 4760-4774
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 4760-4774
-
-
Wu, C.1
So, J.2
Davis-Dusenbery, B.N.3
Qi, H.H.4
Bloch, D.B.5
Shi, Y.6
Lagna, G.7
Hata, A.8
-
44
-
-
52149102253
-
Prolyl 4-hydroxylation regulates Argonaute 2 stability
-
Qi, H. H., Ongusaha, P. P., Myllyharju, J., Cheng, D., Pakkanen, O., Shi, Y., Lee, S. W., Peng, J., and Shi, Y. (2008) Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature 455, 421-424
-
(2008)
Nature
, vol.455
, pp. 421-424
-
-
Qi, H.H.1
Ongusaha, P.P.2
Myllyharju, J.3
Cheng, D.4
Pakkanen, O.5
Shi, Y.6
Lee, S.W.7
Peng, J.8
Shi, Y.9
-
45
-
-
79952361320
-
Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels
-
Bennasser, Y., Chable-Bessia, C., Triboulet, R., Gibbings, D., Gwizdek, C., Dargemont, C., Kremer, E. J., Voinnet, O., and Benkirane, M. (2011) Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels. Nat. Struct. Mol. Biol. 18, 323-327
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 323-327
-
-
Bennasser, Y.1
Chable-Bessia, C.2
Triboulet, R.3
Gibbings, D.4
Gwizdek, C.5
Dargemont, C.6
Kremer, E.J.7
Voinnet, O.8
Benkirane, M.9
-
46
-
-
23944477867
-
Extensive variation in the 5′-UTR of Dicer mRNAs influences translational efficiency
-
DOI 10.1016/j.bbrc.2005.07.138, PII S0006291X05016293
-
Singh, S., Bevan, S. C., Patil, K., Newton, D. C., and Marsden, P. A. (2005) Extensive variation in the 5′-UTR of Dicer mRNAs influences translational efficiency. Biochem. Biophys. Res. Commun. 335, 643-650 (Pubitemid 41188249)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.335
, Issue.3
, pp. 643-650
-
-
Singh, S.1
Bevan, S.C.2
Patil, K.3
Newton, D.C.4
Marsden, P.A.5
-
47
-
-
45349107435
-
Stimuli-dependent cleavage of Dicer during apoptosis
-
DOI 10.1042/BJ20071461
-
Matskevich, A. A., and Moelling, K. (2008) Stimuli-dependent cleavage of Dicer during apoptosis. Biochem. J. 412, 527-534 (Pubitemid 351846418)
-
(2008)
Biochemical Journal
, vol.412
, Issue.3
, pp. 527-534
-
-
Matskevich, A.A.1
Moelung, K.2
-
48
-
-
0242266620
-
Dicer is essential for mouse development
-
DOI 10.1038/ng1253
-
Bernstein, E., Kim, S. Y., Carmell, M. A., Murchison, E. P., Alcorn, H., Li, M. Z., Mills, A. A., Elledge, S. J., Anderson, K. V., and Hannon, G. J. (2003) Dicer is essential for mouse development. Nat. Genet. 35, 215-217 (Pubitemid 37363172)
-
(2003)
Nature Genetics
, vol.35
, Issue.3
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
Murchison, E.P.4
Alcorn, H.5
Li, M.Z.6
Mills, A.A.7
Elledge, S.J.8
Anderson, K.V.9
Hannon, G.J.10
-
49
-
-
35748958766
-
Essential role for Dicer during skeletal muscle development
-
DOI 10.1016/j.ydbio.2007.08.032, PII S0012160607012948
-
O'Rourke, J. R., Georges, S. A., Seay, H. R., Tapscott, S. J., McManus, M. T., Goldhamer, D. J., Swanson, M. S., and Harfe, B. D. (2007) Essential role for Dicer during skeletal muscle development. Dev. Biol. 311, 359-368 (Pubitemid 350046531)
-
(2007)
Developmental Biology
, vol.311
, Issue.2
, pp. 359-368
-
-
O'Rourke, J.R.1
Georges, S.A.2
Seay, H.R.3
Tapscott, S.J.4
McManus, M.T.5
Goldhamer, D.J.6
Swanson, M.S.7
Harfe, B.D.8
-
50
-
-
34447261382
-
Cerebellar neurodegeneration in the absence of microRNAs
-
DOI 10.1084/jem.20070823
-
Schaefer, A., O'Carroll, D., Tan, C. L., Hillman, D., Sugimori, M., Llinas, R., and Greengard, P. (2007) Cerebellar neurodegeneration in the absence of microRNAs. J. Exp. Med. 204, 1553-1558 (Pubitemid 47048023)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.7
, pp. 1553-1558
-
-
Schaefer, A.1
O'Carroll, D.2
Chan, L.T.3
Hillman, D.4
Sugimori, M.5
Llinas, R.6
Greengard, P.7
-
51
-
-
41149147013
-
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
-
DOI 10.1073/pnas.0710228105
-
Chen, J. F., Murchison, E. P., Tang, R., Callis, T. E., Tatsuguchi, M., Deng, Z., Rojas, M., Hammond, S. M., Schneider, M. D., Selzman, C. H., Meissner, G., Patterson, C., Hannon, G. J., and Wang, D. Z. (2008) Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl. Acad. Sci. U.S.A. 105, 2111-2116 (Pubitemid 351439473)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 2111-2116
-
-
Chen, J.-F.1
Murchison, E.P.2
Tang, R.3
Callis, T.E.4
Tatsuguchi, M.5
Deng, Z.6
Rojas, M.7
Hammond, S.M.8
Schneider, M.D.9
Selzman, C.H.10
Meissner, G.11
Patterson, C.12
Hannon, G.J.13
Wang, D.-Z.14
-
52
-
-
55749103053
-
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease
-
Harvey, S. J., Jarad, G., Cunningham, J., Goldberg, S., Schermer, B., Harfe, B. D., McManus, M. T., Benzing, T., and Miner, J. H. (2008) Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J. Am. Soc. Nephrol. 19, 2150-2158
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 2150-2158
-
-
Harvey, S.J.1
Jarad, G.2
Cunningham, J.3
Goldberg, S.4
Schermer, B.5
Harfe, B.D.6
McManus, M.T.7
Benzing, T.8
Miner, J.H.9
-
54
-
-
81755189071
-
MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development
-
Singh, M. K., Lu, M. M., Massera, D., and Epstein, J. A. (2011) MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development. J. Biol. Chem. 286, 41036-41045
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 41036-41045
-
-
Singh, M.K.1
Lu, M.M.2
Massera, D.3
Epstein, J.A.4
-
55
-
-
54549113030
-
The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
-
Kaelin, W. G., Jr. (2008) The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat. Rev. Cancer 8, 865-873
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 865-873
-
-
Kaelin Jr., W.G.1
-
56
-
-
0036174191
-
Repression of α-fetoprotein gene expression under hypoxic conditions in human hepatoma cells: Characterization of a negative hypoxia response element that mediates opposite effects of hypoxia inducible factor-1 and c-Myc
-
Mazure, N. M., Chauvet, C., Bois-Joyeux, B., Bernard, M. A., Nacer-Chérif, H., and Danan, J. L. (2002) Repression of α-fetoprotein gene expression under hypoxic conditions in human hepatoma cells: characterization of a negative hypoxia response element that mediates opposite effects of hypoxia inducible factor-1 and c-Myc. Cancer Res. 62, 1158-1165 (Pubitemid 34160303)
-
(2002)
Cancer Research
, vol.62
, Issue.4
, pp. 1158-1165
-
-
Mazure, N.M.1
Chauvet, C.2
Bois-Joyeux, B.3
Bernard, M.-A.4
Nacer-Cherif, H.5
Danan, J.-L.6
-
57
-
-
25144457125
-
Transcriptional repression of human cad gene by hypoxia inducible factor-1α
-
DOI 10.1093/nar/gki839
-
Chen, K. F., Lai, Y. Y., Sun, H. S., and Tsai, S. J. (2005) Transcriptional repression of human cad gene by hypoxia inducible factor-1α. Nucleic Acids Res. 33, 5190-5198 (Pubitemid 41487827)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.16
, pp. 5190-5198
-
-
Chen, K.-F.1
Lai, Y.-Y.2
Sun, H.S.3
Tsai, S.-J.4
-
58
-
-
28544446113
-
HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia
-
DOI 10.1084/jem.20050177
-
Eltzschig, H. K., Abdulla, P., Hoffman, E., Hamilton, K. E., Daniels, D., Schönfeld, C., Löffler, M., Reyes, G., Duszenko, M., Karhausen, J., Robinson, A., Westerman, K. A., Coe, I. R., and Colgan, S. P. (2005) HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia. J. Exp. Med. 202, 1493-1505 (Pubitemid 41746596)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.11
, pp. 1493-1505
-
-
Eltzschig, H.K.1
Abdulla, P.2
Hoffman, E.3
Hamilton, K.E.4
Daniels, D.5
Schonfeld, C.6
Loffler, M.7
Reyes, G.8
Duszenko, M.9
Karhausen, J.10
Robinson, A.11
Westerman, K.A.12
Coe, I.R.13
Colgan, S.P.14
-
59
-
-
33845724527
-
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
-
DOI 10.1128/MCB.00892-06
-
Evans, A. J., Russell, R. C., Roche, O., Burry, T. N., Fish, J. E., Chow, V. W., Kim, W. Y., Saravanan, A., Maynard, M. A., Gervais, M. L., Sufan, R. I., Roberts, A. M., Wilson, L. A., Betten, M., Vandewalle, C., Berx, G., Marsden, P. A., Irwin, M. S., Teh, B. T., Jewett, M. A., and Ohh, M. (2007) VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail. Mol. Cell. Biol. 27, 157-169 (Pubitemid 46013241)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.1
, pp. 157-169
-
-
Evans, A.J.1
Russell, R.C.2
Roche, O.3
Burry, T.N.4
Fish, J.E.5
Chow, V.W.K.6
Kim, W.Y.7
Saravanan, A.8
Maynard, M.A.9
Gervais, M.L.10
Sufan, R.I.11
Roberts, A.M.12
Wilson, L.A.13
Betten, M.14
Vandewalle, C.15
Berx, G.16
Marsden, P.A.17
Irwin, M.S.18
Teh, B.T.19
Jewett, M.A.S.20
Ohh, M.21
more..
-
60
-
-
61949090107
-
Regulation of endocytosis via the oxygen-sensing pathway
-
Wang, Y., Roche, O., Yan, M. S., Finak, G., Evans, A. J., Metcalf, J. L., Hast, B. E., Hanna, S. C., Wondergem, B., Furge, K. A., Irwin, M. S., Kim, W. Y., Teh, B. T., Grinstein, S., Park, M., Marsden, P. A., and Ohh, M. (2009) Regulation of endocytosis via the oxygen-sensing pathway. Nat. Med. 15, 319-324
-
(2009)
Nat. Med.
, vol.15
, pp. 319-324
-
-
Wang, Y.1
Roche, O.2
Yan, M.S.3
Finak, G.4
Evans, A.J.5
Metcalf, J.L.6
Hast, B.E.7
Hanna, S.C.8
Wondergem, B.9
Furge, K.A.10
Irwin, M.S.11
Kim, W.Y.12
Teh, B.T.13
Grinstein, S.14
Park, M.15
Marsden, P.A.16
Ohh, M.17
-
61
-
-
13444305306
-
TRED: A Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies
-
DOI 10.1093/nar/gki004
-
Zhao, F., Xuan, Z., Liu, L., and Zhang, M. Q. (2005) TRED: a transcriptional regulatory element database and a platform for in silico gene regulation studies. Nucleic Acids Res. 33, D103-D107 (Pubitemid 40207839)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.DATABASE ISS.
-
-
Zhao, F.1
Xuan, Z.2
Liu, L.3
Zhang, M.Q.4
-
62
-
-
33846107777
-
TRED: A transcriptional regulatory element database, new entries and other development
-
DOI 10.1093/nar/gkl1041
-
Jiang, C., Xuan, Z., Zhao, F., and Zhang, M. Q. (2007) TRED: a transcriptional regulatory element database, new entries and other development. Nucleic Acids Res. 35, D137-D140 (Pubitemid 46056185)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.SUPPL. 1
-
-
Jiang, C.1
Xuan, Z.2
Zhao, F.3
Zhang, M.Q.4
-
63
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza, G. L., and Wang, G. L. (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol. 12, 5447-5454
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
64
-
-
28344435137
-
Role of elongin-binding domain of von hippel lindau gene product on HuR-mediated VPF/VEGF mRNA stability in renal cell carcinoma
-
DOI 10.1038/sj.onc.1208912, PII 1208912
-
Datta, K., Mondal, S., Sinha, S., Li, J., Wang, E., Knebelmann, B., Karumanchi, S. A., and Mukhopadhyay, D. (2005) Role of elongin-binding domain of von Hippel Lindau gene product on HuR-mediated VPF/VEGF mRNA stability in renal cell carcinoma. Oncogene 24, 7850-7858 (Pubitemid 41715191)
-
(2005)
Oncogene
, vol.24
, Issue.53
, pp. 7850-7858
-
-
Datta, K.1
Mondal, S.2
Sinha, S.3
Li, J.4
Wang, E.5
Knebelmann, B.6
Karumanchi, S.A.7
Mukhopadhyay, D.8
-
65
-
-
0035955745
-
The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression
-
Pioli, P. A., and Rigby, W. F. (2001) The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression. J. Biol. Chem. 276, 40346-40352
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40346-40352
-
-
Pioli, P.A.1
Rigby, W.F.2
-
66
-
-
84861845402
-
The updated biology of hypoxia-inducible factor
-
Greer, S. N., Metcalf, J. L., Wang, Y., and Ohh, M. (2012) The updated biology of hypoxia-inducible factor. EMBO J. 31, 2448-2460
-
(2012)
EMBO J.
, vol.31
, pp. 2448-2460
-
-
Greer, S.N.1
Metcalf, J.L.2
Wang, Y.3
Ohh, M.4
-
67
-
-
80052277906
-
Control of TH17/Treg balance by hypoxia-inducible factor 1
-
Dang, E. V., Barbi, J., Yang, H. Y., Jinasena, D., Yu, H., Zheng, Y., Bordman, Z., Fu, J., Kim, Y., Yen, H. R., Luo, W., Zeller, K., Shimoda, L., Topalian, S. L., Semenza, G. L., Dang, C. V., Pardoll, D. M., and Pan, F. (2011) Control of TH17/Treg balance by hypoxia-inducible factor 1. Cell 146, 772-784
-
(2011)
Cell
, vol.146
, pp. 772-784
-
-
Dang, E.V.1
Barbi, J.2
Yang, H.Y.3
Jinasena, D.4
Yu, H.5
Zheng, Y.6
Bordman, Z.7
Fu, J.8
Kim, Y.9
Yen, H.R.10
Luo, W.11
Zeller, K.12
Shimoda, L.13
Topalian, S.L.14
Semenza, G.L.15
Dang, C.V.16
Pardoll, D.M.17
Pan, F.18
-
68
-
-
77950878463
-
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline
-
Caruso, P., MacLean, M. R., Khanin, R., McClure, J., Soon, E., Southgate, M., MacDonald, R. A., Greig, J. A., Robertson, K. E., Masson, R., Denby, L., Dempsie, Y., Long, L., Morrell, N. W., and Baker, A. H. (2010) Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline. Arterioscler. Thromb. Vasc. Biol. 30, 716-723
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 716-723
-
-
Caruso, P.1
MacLean, M.R.2
Khanin, R.3
McClure, J.4
Soon, E.5
Southgate, M.6
MacDonald, R.A.7
Greig, J.A.8
Robertson, K.E.9
Masson, R.10
Denby, L.11
Dempsie, Y.12
Long, L.13
Morrell, N.W.14
Baker, A.H.15
-
69
-
-
77953183812
-
A Dicer-independent miRNA biogenesis pathway that requires Ago catalysis
-
Cheloufi, S., Dos Santos, C. O., Chong, M. M., and Hannon, G. J. (2010) A Dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 465, 584-589
-
(2010)
Nature
, vol.465
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.O.2
Chong, M.M.3
Hannon, G.J.4
-
70
-
-
77956995245
-
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis
-
Yang, J. S., Maurin, T., Robine, N., Rasmussen, K. D., Jeffrey, K. L., Chandwani, R., Papapetrou, E. P., Sadelain, M., O'Carroll, D., and Lai, E. C. (2010) Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc. Natl. Acad. Sci. U.S.A. 107, 15163-15168
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 15163-15168
-
-
Yang, J.S.1
Maurin, T.2
Robine, N.3
Rasmussen, K.D.4
Jeffrey, K.L.5
Chandwani, R.6
Papapetrou, E.P.7
Sadelain, M.8
O'Carroll, D.9
Lai, E.C.10
-
71
-
-
84859963228
-
Biogenesis of mammalian microRNAs by a non-canonical processing pathway
-
Havens, M. A., Reich, A. A., Duelli, D. M., and Hastings, M. L. (2012) Biogenesis of mammalian microRNAs by a non-canonical processing pathway. Nucleic Acids Res. 40, 4626-4640
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 4626-4640
-
-
Havens, M.A.1
Reich, A.A.2
Duelli, D.M.3
Hastings, M.L.4
-
72
-
-
79952364512
-
Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells
-
Baccarini, A., Chauhan, H., Gardner, T. J., Jayaprakash, A. D., Sachidanandam, R., and Brown, B. D. (2011) Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells. Curr. Biol. 21, 369-376
-
(2011)
Curr. Biol.
, vol.21
, pp. 369-376
-
-
Baccarini, A.1
Chauhan, H.2
Gardner, T.J.3
Jayaprakash, A.D.4
Sachidanandam, R.5
Brown, B.D.6
-
73
-
-
70349453924
-
Active turnover modulates mature microRNA activity in Caenorhabditis elegans
-
Chatterjee, S., and Grosshans, H. (2009) Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461, 546 -549
-
(2009)
Nature
, vol.461
, pp. 546-549
-
-
Chatterjee, S.1
Grosshans, H.2
-
74
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
DOI 10.1038/nature03702
-
Lu, J., Getz, G., Miska, E. A., Alvarez-Saavedra, E., Lamb, J., Peck, D., Sweet-Cordero, A., Ebert, B. L., Mak, R. H., Ferrando, A. A., Downing, J. R., Jacks, T., Horvitz, H. R., and Golub, T. R. (2005) MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (Pubitemid 40839735)
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
75
-
-
34447504549
-
Oxygen, a source of life and stress
-
Brahimi-Horn, M. C., and Pouysségur, J. (2007) Oxygen, a source of life and stress. FEBS Lett. 581, 3582-3591
-
(2007)
FEBS Lett.
, vol.581
, pp. 3582-3591
-
-
Brahimi-Horn, M.C.1
Pouysségur, J.2
-
76
-
-
0346094457
-
Prediction of Mammalian MicroRNA Targets
-
DOI 10.1016/S0092-8674(03)01018-3
-
Lewis, B. P., Shih, I. H., Jones-Rhoades, M. W., Bartel, D. P., and Burge, C. B. (2003) Prediction of mammalian microRNA targets. Cell 115, 787-798 (Pubitemid 38058492)
-
(2003)
Cell
, vol.115
, Issue.7
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.-H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
77
-
-
60949102130
-
Dicer is regulated by cellular stresses and interferons
-
Wiesen, J. L., and Tomasi, T. B. (2009) Dicer is regulated by cellular stresses and interferons. Mol. Immunol. 46, 1222-1228
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1222-1228
-
-
Wiesen, J.L.1
Tomasi, T.B.2
-
78
-
-
58049213696
-
Dicer, Drosha, and outcomes in patients with ovarian cancer
-
Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R., Urbauer, D., Pennacchio, L. A., Cheng, J. F., Nick, A. M., Deavers, M. T., Mourad-Zeidan, A., Wang, H., Mueller, P., Lenburg, M. E., Gray, J. W., Mok, S., Birrer, M. J., Lopez-Berestein, G., Coleman, R. L., Bar-Eli, M., and Sood, A. K. (2008) Dicer, Drosha, and outcomes in patients with ovarian cancer. N. Engl. J. Med. 359, 2641-2650
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 2641-2650
-
-
Merritt, W.M.1
Lin, Y.G.2
Han, L.Y.3
Kamat, A.A.4
Spannuth, W.A.5
Schmandt, R.6
Urbauer, D.7
Pennacchio, L.A.8
Cheng, J.F.9
Nick, A.M.10
Deavers, M.T.11
Mourad-Zeidan, A.12
Wang, H.13
Mueller, P.14
Lenburg, M.E.15
Gray, J.W.16
Mok, S.17
Birrer, M.J.18
Lopez-Berestein, G.19
Coleman, R.L.20
Bar-Eli, M.21
Sood, A.K.22
more..
-
79
-
-
72549115018
-
Dicer1 functions as a haploinsufficient tumor suppressor
-
Kumar, M. S., Pester, R. E., Chen, C. Y., Lane, K., Chin, C., Lu, J., Kirsch, D. G., Golub, T. R., and Jacks, T. (2009) Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev. 23, 2700-2704
-
(2009)
Genes Dev.
, vol.23
, pp. 2700-2704
-
-
Kumar, M.S.1
Pester, R.E.2
Chen, C.Y.3
Lane, K.4
Chin, C.5
Lu, J.6
Kirsch, D.G.7
Golub, T.R.8
Jacks, T.9
-
80
-
-
77952019174
-
Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells
-
Jakymiw, A., Patel, R. S., Deming, N., Bhattacharyya, I., Shah, P., Lamont, R. J., Stewart, C. M., Cohen, D. M., and Chan, E. K. (2010) Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosomes Cancer 49, 549-559
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 549-559
-
-
Jakymiw, A.1
Patel, R.S.2
Deming, N.3
Bhattacharyya, I.4
Shah, P.5
Lamont, R.J.6
Stewart, C.M.7
Cohen, D.M.8
Chan, E.K.9
-
81
-
-
77953898940
-
A microRNA targeting dicer for metastasis control
-
Martello, G., Rosato, A., Ferrari, F., Manfrin, A., Cordenonsi, M., Dupont, S., Enzo, E., Guzzardo, V., Rondina, M., Spruce, T., Parenti, A. R., Daidone, M. G., Bicciato, S., and Piccolo, S. (2010) A microRNA targeting dicer for metastasis control. Cell 141, 1195-1207
-
(2010)
Cell
, vol.141
, pp. 1195-1207
-
-
Martello, G.1
Rosato, A.2
Ferrari, F.3
Manfrin, A.4
Cordenonsi, M.5
Dupont, S.6
Enzo, E.7
Guzzardo, V.8
Rondina, M.9
Spruce, T.10
Parenti, A.R.11
Daidone, M.G.12
Bicciato, S.13
Piccolo, S.14
-
82
-
-
57549098807
-
The catalogue of somatic mutations in cancer (COSMIC)
-
Chapter 10, Unit 10.11
-
Forbes, S. A., Bhamra, G., Bamford, S., Dawson, E., Kok, C., Clements, J., Menzies, A., Teague, J. W., Futreal, P. A., and Stratton, M. R. (2008) The catalogue of somatic mutations in cancer (COSMIC). Curr. Protoc. Hum. Genet. Chapter 10, Unit 10.11
-
(2008)
Curr. Protoc. Hum. Genet.
-
-
Forbes, S.A.1
Bhamra, G.2
Bamford, S.3
Dawson, E.4
Kok, C.5
Clements, J.6
Menzies, A.7
Teague, J.W.8
Futreal, P.A.9
Stratton, M.R.10
|