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Volumn 9, Issue 1, 2013, Pages 28-38

Nanomedicine applications towards the cure of HIV

Author keywords

Drug development; HIV eradication; HIV vaccine; Memory T cells

Indexed keywords

ANTIRETROVIRAL DRUGS; ANTIRETROVIRALS; CLINICAL TRIAL; DRUG DEVELOPMENT; HIV ERADICATION; INFECTED CELLS; LONG LASTING; MEMORY T CELLS; MICROBICIDES; T CELLS; T-CELL RESPONSE; VIRAL LOAD; VIRUS ELIMINATION;

EID: 84871416782     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.05.012     Document Type: Review
Times cited : (45)

References (80)
  • 1
    • 0020596551 scopus 로고
    • Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
    • Barré-Sinoussi F., Chermann J.C., Rey F., Nugeyre M.T., Chamaret S., et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 1993, 220:868-871.
    • (1993) Science , vol.220 , pp. 868-871
    • Barré-Sinoussi, F.1    Chermann, J.C.2    Rey, F.3    Nugeyre, M.T.4    Chamaret, S.5
  • 3
    • 0037195631 scopus 로고    scopus 로고
    • Historical essay. The early years of HIV/AIDS
    • Gallo R.C. Historical essay. The early years of HIV/AIDS. Science 2002, 298:1728-1730.
    • (2002) Science , vol.298 , pp. 1728-1730
    • Gallo, R.C.1
  • 4
    • 0345097633 scopus 로고    scopus 로고
    • The discovery of HIV as the cause of AIDS
    • Gallo R.C., Montagnier L. The discovery of HIV as the cause of AIDS. N Engl J Med 2003, 394:2283-2285.
    • (2003) N Engl J Med , vol.394 , pp. 2283-2285
    • Gallo, R.C.1    Montagnier, L.2
  • 5
    • 79451471817 scopus 로고    scopus 로고
    • UNAIDS Report on the Global AIDS Epidemic
    • UNAIDS Report on the Global AIDS Epidemic 2010. http://www.unaids.org/globalreport/Global_report.htm.
    • (2010)
  • 6
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced Human Immunodeficiency Virus infection
    • Palella F.J., Delaney K.M., Moorman A.C., Loveless M.O., Fuhrer J., et al. Declining morbidity and mortality among patients with advanced Human Immunodeficiency Virus infection. New Engl J Med 1998, 338:853-860.
    • (1998) New Engl J Med , vol.338 , pp. 853-860
    • Palella, F.J.1    Delaney, K.M.2    Moorman, A.C.3    Loveless, M.O.4    Fuhrer, J.5
  • 7
    • 30944440882 scopus 로고    scopus 로고
    • Causes of the decline in AIDS deaths, United States, 1995-2002: Prevention, treatment or both?
    • Holtgrave D.R. Causes of the decline in AIDS deaths, United States, 1995-2002: Prevention, treatment or both?. Int J STD AIDS 2005, 16:777-781.
    • (2005) Int J STD AIDS , vol.16 , pp. 777-781
    • Holtgrave, D.R.1
  • 8
    • 72849122861 scopus 로고    scopus 로고
    • Racial and sex disparities in life expectancy losses among HIV-infected persons in the United States: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy
    • Losina E., Schackman B.R., Sadownik S.N., Gebo K.A., Walensky R.P., et al. Racial and sex disparities in life expectancy losses among HIV-infected persons in the United States: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy. Clin Infect Dis 2009, 49:1570-1578.
    • (2009) Clin Infect Dis , vol.49 , pp. 1570-1578
    • Losina, E.1    Schackman, B.R.2    Sadownik, S.N.3    Gebo, K.A.4    Walensky, R.P.5
  • 9
    • 42449086328 scopus 로고    scopus 로고
    • CD4+ count and risk of NON-AIDS diseases following initial treatment for HIV infection
    • Baker J.V., Peng G., Rapkin J., Abrams D.I., Silverberg M.J., et al. CD4+ count and risk of NON-AIDS diseases following initial treatment for HIV infection. AIDS 2008, 22:841-848.
    • (2008) AIDS , vol.22 , pp. 841-848
    • Baker, J.V.1    Peng, G.2    Rapkin, J.3    Abrams, D.I.4    Silverberg, M.J.5
  • 10
    • 70449411747 scopus 로고    scopus 로고
    • HIV-1 residual viremia correlates with persisitent T-cell activation in poor immunological responders to combination antiretroviral therapy
    • Mavigner M., Delobel P., Cazabat M., Dubois M., L'faqihi-Olive F.E., et al. HIV-1 residual viremia correlates with persisitent T-cell activation in poor immunological responders to combination antiretroviral therapy. PLoS One 2009, 4:e7658.
    • (2009) PLoS One , vol.4
    • Mavigner, M.1    Delobel, P.2    Cazabat, M.3    Dubois, M.4    L'faqihi-Olive, F.E.5
  • 11
    • 0034979270 scopus 로고    scopus 로고
    • Picker LJ and Koup RA Decay kinetics of Human Immunodeficiency Virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy
    • Casazza J.P., Betts M.R. Picker LJ and Koup RA Decay kinetics of Human Immunodeficiency Virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy. J Virol 2001, 75:6508-6516.
    • (2001) J Virol , vol.75 , pp. 6508-6516
    • Casazza, J.P.1    Betts, M.R.2
  • 12
    • 79953117041 scopus 로고    scopus 로고
    • Evidence for the cure of HIV infection by CCR5D32/D32 stem cell transplantation
    • Allers K., Hütter G., Hofmann J., Loddenkemper C., Rieger K., et al. Evidence for the cure of HIV infection by CCR5D32/D32 stem cell transplantation. Blood 2011, 117:2791-2799.
    • (2011) Blood , vol.117 , pp. 2791-2799
    • Allers, K.1    Hütter, G.2    Hofmann, J.3    Loddenkemper, C.4    Rieger, K.5
  • 14
    • 34548689151 scopus 로고    scopus 로고
    • Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy
    • Deeks S.G., Walker B.D. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 2007, 27:406-416.
    • (2007) Immunity , vol.27 , pp. 406-416
    • Deeks, S.G.1    Walker, B.D.2
  • 15
    • 79953000877 scopus 로고    scopus 로고
    • A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response
    • Hatano H., Hayes T.L., Dahl V., Sinclair E., Lee T.H., et al. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. J Infect Dis 2011, 203:894-897.
    • (2011) J Infect Dis , vol.203 , pp. 894-897
    • Hatano, H.1    Hayes, T.L.2    Dahl, V.3    Sinclair, E.4    Lee, T.H.5
  • 16
    • 84863337769 scopus 로고    scopus 로고
    • Stimulation of HIV-1-Specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
    • Shan L., Dend K., Shroff N.S., Durand C.M., Alireza S., et al. Stimulation of HIV-1-Specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 2012, 36:1-11.
    • (2012) Immunity , vol.36 , pp. 1-11
    • Shan, L.1    Dend, K.2    Shroff, N.S.3    Durand, C.M.4    Alireza, S.5
  • 17
    • 33748669829 scopus 로고    scopus 로고
    • Nanoparticulate drug carriers for delivery of HIV/AIDS therapy to viral reservoir sites
    • Vyas T.K., Shah L., Amiji M.M. Nanoparticulate drug carriers for delivery of HIV/AIDS therapy to viral reservoir sites. Expert Opin Drug Deliv 2006, 3:613-628.
    • (2006) Expert Opin Drug Deliv , vol.3 , pp. 613-628
    • Vyas, T.K.1    Shah, L.2    Amiji, M.M.3
  • 18
    • 54049123870 scopus 로고    scopus 로고
    • Role of nanotechnology in HIV/AIDS treatment: potential to overcome the viral reservoir challenge
    • Amiji M.M., Vyas T.K., Shah L.K. Role of nanotechnology in HIV/AIDS treatment: potential to overcome the viral reservoir challenge. Discov Med 2006, 6:157-162.
    • (2006) Discov Med , vol.6 , pp. 157-162
    • Amiji, M.M.1    Vyas, T.K.2    Shah, L.K.3
  • 19
    • 68249144974 scopus 로고    scopus 로고
    • NanoART, neuroAIDS and CNS drug delivery
    • Nowacek A., Gendelman H.E. NanoART, neuroAIDS and CNS drug delivery. Nanomedicine 2009, 4:557-574.
    • (2009) Nanomedicine , vol.4 , pp. 557-574
    • Nowacek, A.1    Gendelman, H.E.2
  • 20
    • 79953689313 scopus 로고    scopus 로고
    • Activation of latent HIV using drug-loaded nanoparticles
    • Kovochich M., Marsden M.D., Zack J.A. Activation of latent HIV using drug-loaded nanoparticles. PLoS One 2011, 6:e18270.
    • (2011) PLoS One , vol.6
    • Kovochich, M.1    Marsden, M.D.2    Zack, J.A.3
  • 21
    • 39749120051 scopus 로고    scopus 로고
    • PH-dependent interactions of indinavir and lipids in nanoparticles and their ability to enatrap a solute
    • Choi S.U., Bui T., Ho R.J. pH-dependent interactions of indinavir and lipids in nanoparticles and their ability to enatrap a solute. J Pharm Sci 2008, 97:931-943.
    • (2008) J Pharm Sci , vol.97 , pp. 931-943
    • Choi, S.U.1    Bui, T.2    Ho, R.J.3
  • 22
    • 0345687957 scopus 로고    scopus 로고
    • Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: a proof of concept study i HIV-2287-infected macaques
    • Kinman L., Brodie S.J., Tsai C.C., Bui T., Larsen K., et al. Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: a proof of concept study i HIV-2287-infected macaques. J Acquir Immune Defic Syndr 2003, 34:387-397.
    • (2003) J Acquir Immune Defic Syndr , vol.34 , pp. 387-397
    • Kinman, L.1    Brodie, S.J.2    Tsai, C.C.3    Bui, T.4    Larsen, K.5
  • 23
    • 77955977615 scopus 로고    scopus 로고
    • AIDS treatment and novel anti-HIV compounds improved by nanotechnology
    • Ma X., Wang D., Wu Y., Ho R.J.Y., Jia L., et al. AIDS treatment and novel anti-HIV compounds improved by nanotechnology. AAPS J 2010, 12:272-278.
    • (2010) AAPS J , vol.12 , pp. 272-278
    • Ma, X.1    Wang, D.2    Wu, Y.3    Ho, R.J.Y.4    Jia, L.5
  • 24
    • 75949086100 scopus 로고    scopus 로고
    • Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailabilty
    • Chiappetta D.A., Hocht C., Taira C., Sosnik A. Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailabilty. Nanomedicine 2010, 5:11-23.
    • (2010) Nanomedicine , vol.5 , pp. 11-23
    • Chiappetta, D.A.1    Hocht, C.2    Taira, C.3    Sosnik, A.4
  • 25
    • 67449119172 scopus 로고    scopus 로고
    • Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment
    • Baert L., van't Klooster G., Dries W., François M., Wouters A., et al. Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment. Eur J Pharm Biopharm 2009, 72:502-508.
    • (2009) Eur J Pharm Biopharm , vol.72 , pp. 502-508
    • Baert, L.1    van't Klooster, G.2    Dries, W.3    François, M.4    Wouters, A.5
  • 26
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q., Abdool Karim S.S., Frohlich J.A., Grobler A.C., Baxter C., et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010, 329:1168-1174.
    • (2010) Science , vol.329 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2    Frohlich, J.A.3    Grobler, A.C.4    Baxter, C.5
  • 27
    • 84871464191 scopus 로고    scopus 로고
    • NIH Discontinues Tenofovir Vaginal Gel in 'VOICE' HIV Prevention Study.
    • NIH Discontinues Tenofovir Vaginal Gel in 'VOICE' HIV Prevention Study. http://www.nih.gov/news/health/nov2011/niaid-25.htm.
  • 28
    • 60149111908 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
    • Lai S.K., Wang Y.Y., Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv Drug Deliv Rev 2009, 61:158-171.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 158-171
    • Lai, S.K.1    Wang, Y.Y.2    Hanes, J.3
  • 29
    • 79958296573 scopus 로고    scopus 로고
    • Mucoadhesive nanosystems for vaginal microbicide development: friend or foe?
    • Das Neves J., Amiji M., Sarmento B. Mucoadhesive nanosystems for vaginal microbicide development: friend or foe?. John Wiley and Sons Inc 2011, 3:389-399.
    • (2011) John Wiley and Sons Inc , vol.3 , pp. 389-399
    • Das Neves, J.1    Amiji, M.2    Sarmento, B.3
  • 30
    • 34547172248 scopus 로고    scopus 로고
    • Development and in vitro evaluation of surface modified poly (lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine
    • Grabovac V., Bernkop-Schnurch A. Development and in vitro evaluation of surface modified poly (lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine. Drug Dev Ind Pharm 2007, 33:767-774.
    • (2007) Drug Dev Ind Pharm , vol.33 , pp. 767-774
    • Grabovac, V.1    Bernkop-Schnurch, A.2
  • 31
    • 79959641957 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure
    • Wang Y.Y., Lai S.K., So C., Schneider C., Cone R., Hanes J. Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure. PLoS One 2011, 6:e21547.
    • (2011) PLoS One , vol.6
    • Wang, Y.Y.1    Lai, S.K.2    So, C.3    Schneider, C.4    Cone, R.5    Hanes, J.6
  • 32
    • 33846807636 scopus 로고    scopus 로고
    • Evaluation of -2 RANTES vaginal microbicide formulations in a nonhuman primate simian/human immunodeficiency virus (SHIV) challenge model
    • Kish-Catalone T., Pal R., Parrish J., Rose N., Hocker L. Evaluation of -2 RANTES vaginal microbicide formulations in a nonhuman primate simian/human immunodeficiency virus (SHIV) challenge model. AIDS Res Hum Retroviruses 2007, 23:33-42.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 33-42
    • Kish-Catalone, T.1    Pal, R.2    Parrish, J.3    Rose, N.4    Hocker, L.5
  • 33
    • 77955510139 scopus 로고    scopus 로고
    • Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus macaques with RT-SHIV
    • Caron M., Besson G., Etenna S.L., Mintsa-Ndong A., Mourtas S. Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus macaques with RT-SHIV. Virology 2010, 405:225-233.
    • (2010) Virology , vol.405 , pp. 225-233
    • Caron, M.1    Besson, G.2    Etenna, S.L.3    Mintsa-Ndong, A.4    Mourtas, S.5
  • 34
    • 77951725527 scopus 로고    scopus 로고
    • Stimuli-responsive liposome fusion mediated by gold nanoparticles
    • Pornpattananangkul D., Olson S., Aryal S., Sartor M., Huang C.-M., et al. Stimuli-responsive liposome fusion mediated by gold nanoparticles. ACS Nano 2010, 4:1935-1942.
    • (2010) ACS Nano , vol.4 , pp. 1935-1942
    • Pornpattananangkul, D.1    Olson, S.2    Aryal, S.3    Sartor, M.4    Huang, C.-M.5
  • 35
    • 77954403578 scopus 로고    scopus 로고
    • PVP-coated silver nanoparticles block the transmission of cel.l-free and cell-associated HIV-1 in human cervical culture
    • Lara H.H., Ixtepan-Turrent L., Garza-Trevino E.N., Rodriguez-Padilla C. PVP-coated silver nanoparticles block the transmission of cel.l-free and cell-associated HIV-1 in human cervical culture. J Nanobiotechnol 2010, 8:1-11.
    • (2010) J Nanobiotechnol , vol.8 , pp. 1-11
    • Lara, H.H.1    Ixtepan-Turrent, L.2    Garza-Trevino, E.N.3    Rodriguez-Padilla, C.4
  • 36
    • 70349557913 scopus 로고    scopus 로고
    • Multivalent manno-glyconanoparticles inhibit DC-SIGN-mediated HIV-1 transinfection of human T cells
    • Martinez-Avila O., Bedoya L.M., Marradi M., Clavel C., Alcami J., et al. Multivalent manno-glyconanoparticles inhibit DC-SIGN-mediated HIV-1 transinfection of human T cells. Chem Biochem 2009, 10:1806-1809.
    • (2009) Chem Biochem , vol.10 , pp. 1806-1809
    • Martinez-Avila, O.1    Bedoya, L.M.2    Marradi, M.3    Clavel, C.4    Alcami, J.5
  • 37
  • 38
    • 38949198100 scopus 로고    scopus 로고
    • VivaGel (SPL 7013 Gel): a candidate dendrimer-microbicide for the prevention of HIV and HSV infection
    • Rupp R., Rosenthal S.L., Stanberry L.R. VivaGel (SPL 7013 Gel): a candidate dendrimer-microbicide for the prevention of HIV and HSV infection. Int J Nanomed 2007, 2:561-566.
    • (2007) Int J Nanomed , vol.2 , pp. 561-566
    • Rupp, R.1    Rosenthal, S.L.2    Stanberry, L.R.3
  • 39
    • 0034849493 scopus 로고    scopus 로고
    • Induction of potent immune responses by cationic microparticles with adsorbed Human Immunodeficiency Virus DNA vaccines
    • O'Hagan D., Singh M., Ugozzoli M., Wild C., Barnett S., et al. Induction of potent immune responses by cationic microparticles with adsorbed Human Immunodeficiency Virus DNA vaccines. J Virol 2001, 75:9037-9043.
    • (2001) J Virol , vol.75 , pp. 9037-9043
    • O'Hagan, D.1    Singh, M.2    Ugozzoli, M.3    Wild, C.4    Barnett, S.5
  • 40
    • 84871451104 scopus 로고    scopus 로고
    • Safety of and Immune Response to a Combination HIV Vaccine Regimen in HIV Uninfected Adults.
    • Safety of and Immune Response to a Combination HIV Vaccine Regimen in HIV Uninfected Adults. http://www.clinicaltrials.gov/ct2/show/NCT00073216?term=PLG+HIV&rank=1.
  • 41
    • 79953320203 scopus 로고    scopus 로고
    • A Trimeric, V2-DELETED HIV-1 envelope glycoprotein vaccine elicits potent neutralizing antibodies but limited breadth of neutralization in human volunteers
    • Spearman P., Lally M.A., Elizaga M., Montefiori D., Tomaras G.D., et al. A Trimeric, V2-DELETED HIV-1 envelope glycoprotein vaccine elicits potent neutralizing antibodies but limited breadth of neutralization in human volunteers. J Infect Dis 2011, 203:1165-1173.
    • (2011) J Infect Dis , vol.203 , pp. 1165-1173
    • Spearman, P.1    Lally, M.A.2    Elizaga, M.3    Montefiori, D.4    Tomaras, G.D.5
  • 42
    • 33748762545 scopus 로고    scopus 로고
    • Pathogen recognition and development of particulate vaccines: Does size matter?
    • Xiang S.D., Scholzen A., Minigo A., David C., Apostolopoulos V., et al. Pathogen recognition and development of particulate vaccines: Does size matter?. Methods 2006, 40:1-9.
    • (2006) Methods , vol.40 , pp. 1-9
    • Xiang, S.D.1    Scholzen, A.2    Minigo, A.3    David, C.4    Apostolopoulos, V.5
  • 43
    • 79954556479 scopus 로고    scopus 로고
    • The Janus face of immune stimulation by nanomedicines examples for the good and the bad
    • Lisziewicz J., Szebeni J. The Janus face of immune stimulation by nanomedicines examples for the good and the bad. Eur J Nanomed 2010, http://dx.doi.org/10.3884/0003.1.5.
    • (2010) Eur J Nanomed
    • Lisziewicz, J.1    Szebeni, J.2
  • 44
    • 0027930718 scopus 로고
    • Assembled baculovirus-expressed human papillomavirus type 11 L1 capsid protein virus-like particles are recognized by neutralizing monoclonal antibodies and induce high titres of neutralizing antibodies
    • Christensen N.D., Hopfl R., Diangelo S.L., Cladel N.M., Patrick S.D., et al. Assembled baculovirus-expressed human papillomavirus type 11 L1 capsid protein virus-like particles are recognized by neutralizing monoclonal antibodies and induce high titres of neutralizing antibodies. J Gen Virol 1994, 75:2271-2276.
    • (1994) J Gen Virol , vol.75 , pp. 2271-2276
    • Christensen, N.D.1    Hopfl, R.2    Diangelo, S.L.3    Cladel, N.M.4    Patrick, S.D.5
  • 45
    • 34547912100 scopus 로고    scopus 로고
    • Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection - A randomized trial
    • Hildesheim A., Herrero R., Wacholder S., Rodriguez A.C., Solomon D., et al. Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection - A randomized trial. JAMA 2007, 298:743-753.
    • (2007) JAMA , vol.298 , pp. 743-753
    • Hildesheim, A.1    Herrero, R.2    Wacholder, S.3    Rodriguez, A.C.4    Solomon, D.5
  • 46
    • 0027375070 scopus 로고
    • Immunization of human HIV-seronegative volunteers with recombinant p17/p24:Ty virus-like particles elicits HIV-1 p24-specific cellular and humoral immune responses
    • Martin S.J., Vyakarnam A., Cheingsong-Popov R., Callow D., Jones K.L., et al. Immunization of human HIV-seronegative volunteers with recombinant p17/p24:Ty virus-like particles elicits HIV-1 p24-specific cellular and humoral immune responses. AIDS 1993, 7:1315-1323.
    • (1993) AIDS , vol.7 , pp. 1315-1323
    • Martin, S.J.1    Vyakarnam, A.2    Cheingsong-Popov, R.3    Callow, D.4    Jones, K.L.5
  • 49
    • 67549149326 scopus 로고    scopus 로고
    • Enhanced in VIVO Immunogenicity of SIV Vaccine Candidates with cationic liposome-DNA Complexes In a Rhesus macaque Pilot Study
    • Fairman J., Moore J., Lemieux M., Van Rompay K., Geng Y., Warner J., Abel K. Enhanced in VIVO Immunogenicity of SIV Vaccine Candidates with cationic liposome-DNA Complexes In a Rhesus macaque Pilot Study. Hum Vaccin 2009, 5:141-150.
    • (2009) Hum Vaccin , vol.5 , pp. 141-150
    • Fairman, J.1    Moore, J.2    Lemieux, M.3    Van Rompay, K.4    Geng, Y.5    Warner, J.6    Abel, K.7
  • 50
    • 33646480406 scopus 로고    scopus 로고
    • In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles
    • Reddy S.T., Rehor A., Schmoekel H.G., Hubbell J.A., Swartz M.A. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. J Control Release 2006, 112:26-34.
    • (2006) J Control Release , vol.112 , pp. 26-34
    • Reddy, S.T.1    Rehor, A.2    Schmoekel, H.G.3    Hubbell, J.A.4    Swartz, M.A.5
  • 51
    • 0033516472 scopus 로고    scopus 로고
    • Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cell
    • Diebold S.S., Kursa M., Wagner E., Cotton M., Zenke M. Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cell. J Biol Chem 1999, 274:19087-19094.
    • (1999) J Biol Chem , vol.274 , pp. 19087-19094
    • Diebold, S.S.1    Kursa, M.2    Wagner, E.3    Cotton, M.4    Zenke, M.5
  • 53
    • 68149173128 scopus 로고    scopus 로고
    • In quest of a systematic framework for unifying and defining nanoscience
    • Tomalia D.A. In quest of a systematic framework for unifying and defining nanoscience. J Nanopart Res 2009, 11:1251-1310.
    • (2009) J Nanopart Res , vol.11 , pp. 1251-1310
    • Tomalia, D.A.1
  • 54
    • 78650541311 scopus 로고    scopus 로고
    • A plasmid DNA immunogen expressing fifteen protein antigens and complex virus-like particles (VLP+) mimicking naturally occurring HIV
    • Somogyi E., Xu J., Gudics A., Tóth J., Kovács A., et al. A plasmid DNA immunogen expressing fifteen protein antigens and complex virus-like particles (VLP+) mimicking naturally occurring HIV. Vaccine 2011, 29:744-753.
    • (2011) Vaccine , vol.29 , pp. 744-753
    • Somogyi, E.1    Xu, J.2    Gudics, A.3    Tóth, J.4    Kovács, A.5
  • 55
    • 77952745141 scopus 로고    scopus 로고
    • Rational development of a stable liquid formulation for nanomedicine products
    • Toke E.R., Lorincz O., Somogyi E., Lisziewicz J. Rational development of a stable liquid formulation for nanomedicine products. Int J Pharm 2010, 392:261-267.
    • (2010) Int J Pharm , vol.392 , pp. 261-267
    • Toke, E.R.1    Lorincz, O.2    Somogyi, E.3    Lisziewicz, J.4
  • 57
    • 77957355961 scopus 로고    scopus 로고
    • Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
    • Mouquet H., Scheid J.F., Zoller M.J., Krogsgaard M., Ott R.G., et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature 2010, 467:591-595.
    • (2010) Nature , vol.467 , pp. 591-595
    • Mouquet, H.1    Scheid, J.F.2    Zoller, M.J.3    Krogsgaard, M.4    Ott, R.G.5
  • 58
    • 33750728433 scopus 로고    scopus 로고
    • Targeting dendritic cells with biomaterials: developing the next generation of vaccines
    • Reddy S.T., Swartz M.A., Hubbell J.A. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends Immunol 2006, 27:573-579.
    • (2006) Trends Immunol , vol.27 , pp. 573-579
    • Reddy, S.T.1    Swartz, M.A.2    Hubbell, J.A.3
  • 59
    • 0034607160 scopus 로고    scopus 로고
    • Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery
    • Schaffer D.V., Fidelman N.A., Dan N., Lauffenburger D.A. Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery. Biotech Bioeng 2000, 67:598-606.
    • (2000) Biotech Bioeng , vol.67 , pp. 598-606
    • Schaffer, D.V.1    Fidelman, N.A.2    Dan, N.3    Lauffenburger, D.A.4
  • 60
    • 71349083803 scopus 로고    scopus 로고
    • The heterogeneous nature of polyethylenimine-DNA complex formation affects transient gene expression
    • Han X., Fang Q., Yao F., Wang X., Wang J. The heterogeneous nature of polyethylenimine-DNA complex formation affects transient gene expression. Cytotechnology 2009, 60:63-75.
    • (2009) Cytotechnology , vol.60 , pp. 63-75
    • Han, X.1    Fang, Q.2    Yao, F.3    Wang, X.4    Wang, J.5
  • 61
    • 0037386523 scopus 로고    scopus 로고
    • Efficient active transport of gene nanocarriers to the nucleus
    • Suh J., Wirtz D., Hanes J. Efficient active transport of gene nanocarriers to the nucleus. Proc Natl Acad Sci 2003, 100:3878-3882.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 3878-3882
    • Suh, J.1    Wirtz, D.2    Hanes, J.3
  • 62
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: a renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 2002, 296:301-305.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 63
    • 53849147254 scopus 로고    scopus 로고
    • Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice
    • Nicolas J.F., Guy B. Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice. Expert Rev Vaccines 2008, 7:1201-1214.
    • (2008) Expert Rev Vaccines , vol.7 , pp. 1201-1214
    • Nicolas, J.F.1    Guy, B.2
  • 64
    • 0035112905 scopus 로고    scopus 로고
    • A strikingly constant ratio exists between Langerhans cells and other epidermal cells in human skin. A stereologic study using the optical disector method and the confocal laser scanning microscope
    • Bauer J., Bahmer F.A., Worl J., Neuhuber W., Schuler G., et al. A strikingly constant ratio exists between Langerhans cells and other epidermal cells in human skin. A stereologic study using the optical disector method and the confocal laser scanning microscope. J Invest Dermatol 2001, 116:313-318.
    • (2001) J Invest Dermatol , vol.116 , pp. 313-318
    • Bauer, J.1    Bahmer, F.A.2    Worl, J.3    Neuhuber, W.4    Schuler, G.5
  • 65
    • 0034909893 scopus 로고    scopus 로고
    • Induction of potent human immunodeficiency virus type 1-specific T-cell-restricted immunity by genetically modified dendritic cells
    • Lisziewicz J., Gabrilovich D.I., Varga G., Xu J., Greenberg P.D., et al. Induction of potent human immunodeficiency virus type 1-specific T-cell-restricted immunity by genetically modified dendritic cells. J Virol 2001, 75:7621-7628.
    • (2001) J Virol , vol.75 , pp. 7621-7628
    • Lisziewicz, J.1    Gabrilovich, D.I.2    Varga, G.3    Xu, J.4    Greenberg, P.D.5
  • 67
    • 19944427625 scopus 로고    scopus 로고
    • Control of viral rebound through therapeutic immunization with DermaVir
    • Lisziewicz J., Trocio J., Xu J., Whitman L., Ryder A., et al. Control of viral rebound through therapeutic immunization with DermaVir. AIDS 2005, 19:35-43.
    • (2005) AIDS , vol.19 , pp. 35-43
    • Lisziewicz, J.1    Trocio, J.2    Xu, J.3    Whitman, L.4    Ryder, A.5
  • 68
    • 84860745751 scopus 로고    scopus 로고
    • Single DermaVir immunization: dose-dependent expansion of precursor/memory T cells against all HIV antigens in HIV-1 infected individuals
    • Lisziewicz J., Bakare N., Calarota S.A., Bánhegyi D., Szlávik J. Single DermaVir immunization: dose-dependent expansion of precursor/memory T cells against all HIV antigens in HIV-1 infected individuals. PLoS One 2012, 7:e35416.
    • (2012) PLoS One , vol.7
    • Lisziewicz, J.1    Bakare, N.2    Calarota, S.A.3    Bánhegyi, D.4    Szlávik, J.5
  • 69
    • 44449118581 scopus 로고    scopus 로고
    • HIV-1-Specific T cell precursors with high proliferative capacity correlate with low viremia and high CD4 counts in untreated individuals
    • Calarota S.A., Foli A., Maserati R., Baldanti F., Paolucci S., et al. HIV-1-Specific T cell precursors with high proliferative capacity correlate with low viremia and high CD4 counts in untreated individuals. J Immunol 2008, 180:5907-5915.
    • (2008) J Immunol , vol.180 , pp. 5907-5915
    • Calarota, S.A.1    Foli, A.2    Maserati, R.3    Baldanti, F.4    Paolucci, S.5
  • 70
    • 84871412654 scopus 로고    scopus 로고
    • Repeated-dose transdermal administration of DermaVir, a candidate plasmid DNA-based therapeutic HIV vaccine, is safe and well-tolerated
    • a 61-week analysis of ACTG Study 5176, paper presented at XVIIIth International AIDS Conference, 2010, Vienna, Austria, Abstract # A-240-0111-10145.
    • Rodriguez B, Asmuth D, Matining R, Spritzler J, Li X, et al. Repeated-dose transdermal administration of DermaVir, a candidate plasmid DNA-based therapeutic HIV vaccine, is safe and well-tolerated: a 61-week analysis of ACTG Study 5176, paper presented at XVIIIth International AIDS Conference, 2010, Vienna, Austria, Abstract # A-240-0111-10145.
    • Rodriguez, B.1    Asmuth, D.2    Matining, R.3    Spritzler, J.4    Li, X.5
  • 72
    • 25844482131 scopus 로고    scopus 로고
    • Perils at mucosal front lines for HIV and SIV and their hosts
    • Haase A.T. Perils at mucosal front lines for HIV and SIV and their hosts. Nat Rev Immunol 2005, 5:783-792.
    • (2005) Nat Rev Immunol , vol.5 , pp. 783-792
    • Haase, A.T.1
  • 73
    • 46049096099 scopus 로고    scopus 로고
    • Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection
    • Shen L., Siliciano R.F. Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection. J Allergy Clin Immun 2008, 122:22-28.
    • (2008) J Allergy Clin Immun , vol.122 , pp. 22-28
    • Shen, L.1    Siliciano, R.F.2
  • 74
    • 67249121143 scopus 로고    scopus 로고
    • Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
    • Dinosoa J.B., Kima S.Y., Wiegandc A.M., Palmerc S.E., Ganged S.J., et al. Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A 2009, 106:9403-9408.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9403-9408
    • Dinosoa, J.B.1    Kima, S.Y.2    Wiegandc, A.M.3    Palmerc, S.E.4    Ganged, S.J.5
  • 75
    • 77956856393 scopus 로고    scopus 로고
    • The effect of Raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial
    • Gandhi R.T., Zheng L., Bosch R.Z., Chan E.S., Margolis D.M., et al. The effect of Raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med 2011, 7:1-11.
    • (2011) PLoS Med , vol.7 , pp. 1-11
    • Gandhi, R.T.1    Zheng, L.2    Bosch, R.Z.3    Chan, E.S.4    Margolis, D.M.5
  • 76
    • 77749277080 scopus 로고    scopus 로고
    • Short-course Raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy
    • McMahon D., Jones J., Wiegand A., Gange S.J., Kearney M., et al. Short-course Raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy. Clin Infect Dis 2010, 50:912-919.
    • (2010) Clin Infect Dis , vol.50 , pp. 912-919
    • McMahon, D.1    Jones, J.2    Wiegand, A.3    Gange, S.J.4    Kearney, M.5
  • 77
    • 84871439353 scopus 로고    scopus 로고
    • DermaVir Search Results
    • Accessed 12 January 2012.
    • DermaVir Search Results. Accessed 12 January 2012. http://www.clinicaltrials.gov/ct2/results?term=dermavir.
  • 78
    • 33748856603 scopus 로고    scopus 로고
    • Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases
    • Fuller D.H., Loudon P., Schmaljohn P. Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases. Methods 2006, 40:86-97.
    • (2006) Methods , vol.40 , pp. 86-97
    • Fuller, D.H.1    Loudon, P.2    Schmaljohn, P.3
  • 79
    • 67749142116 scopus 로고    scopus 로고
    • Dendritic cells loaded with HIV-1 p24 proteins adsorbed on surfactant-free anionic PLA nanoparticles induce enhanced cellular immune responses against HIV-1 after vaccination
    • Aline F., Brand D., Pierre J., Roingeard P., Séverine M., et al. Dendritic cells loaded with HIV-1 p24 proteins adsorbed on surfactant-free anionic PLA nanoparticles induce enhanced cellular immune responses against HIV-1 after vaccination. Vaccine 2009, 27:5284-5291.
    • (2009) Vaccine , vol.27 , pp. 5284-5291
    • Aline, F.1    Brand, D.2    Pierre, J.3    Roingeard, P.4    Séverine, M.5
  • 80
    • 84855361060 scopus 로고    scopus 로고
    • Safety and immunogenicity of AN HIV-1 GAG DNA vaccine with or without il-12 and/or il-15 plasmid cytokine adjuvant in healthy, hiv-1 uninfected adults
    • Kalams S.A., Parker S., Jin X., Elizaga M., Metch B. Safety and immunogenicity of AN HIV-1 GAG DNA vaccine with or without il-12 and/or il-15 plasmid cytokine adjuvant in healthy, hiv-1 uninfected adults. PLoS One 2012, 7:E29231.
    • (2012) PLoS One , vol.7
    • Kalams, S.A.1    Parker, S.2    Jin, X.3    Elizaga, M.4    Metch, B.5


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