메뉴 건너뛰기




Volumn 9, Issue 11, 2014, Pages 1595-1612

Comparative biophysical properties of tenofovir-loaded, thiolated and nonthiolated chitosan nanoparticles intended for HIV prevention

Author keywords

HIV prevention; mucoadhesion; nanoparticle; tenofovir; thiolated chitosan; vaginal drug delivery

Indexed keywords

CAVEOLIN; CHITOSAN; NANOPARTICLE; TENOFOVIR; THIOGLYCOLIC ACID; 2-MERCAPTOACETATE; ADENINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; PHOSPHONIC ACID DERIVATIVE; THIOGLYCOLIC ACID DERIVATIVE; THIOL DERIVATIVE;

EID: 84908879621     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.13.136     Document Type: Article
Times cited : (46)

References (75)
  • 4
    • 84908893890 scopus 로고    scopus 로고
    • Eliminate gender inequalities and gender-based abuse and violence and increase thecapacity of women and girls to protect themselves from HIV
    • UNAIDS UNAIDS, Geneva, Switzerland
    • UNAIDS. Eliminate gender inequalities and gender-based abuse and violence and increase thecapacity of women and girls to protect themselves from HIV. In: Global Report UNAIDS Report on the Global AIDS Epidemic 2013. UNAIDS, Geneva, Switzerland, 78-83 (2013).
    • (2013) Global Report UNAIDS Report on the Global AIDS Epidemic 2013 , pp. 78-83
  • 5
    • 0345305700 scopus 로고    scopus 로고
    • The contribution of sexual and reproductive health services to the fight against HIV/AIDS: A review
    • Askew I, Berer M. The contribution of sexual and reproductive health services to the fight against HIV/AIDS: a review. Reprod. Health Matt. 11 (22), 51-73 (2003).
    • (2003) Reprod. Health Matt. , vol.11 , Issue.22 , pp. 51-73
    • Askew, I.1    Berer, M.2
  • 6
    • 22144454301 scopus 로고    scopus 로고
    • The development of vaginal microbicides for the prevention of HIV transmission
    • Weber J, Desai K, Darbyshire J. The development of vaginal microbicides for the prevention of HIV transmission. PLoS Med. 2 (5), e142 (2005).
    • (2005) PLoS Med. , vol.2 , Issue.5 , pp. e142
    • Weber, J.1    Desai, K.2    Darbyshire, J.3
  • 7
    • 51449112802 scopus 로고    scopus 로고
    • A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections
    • Ndesendo VM, Pillay V, Choonara YE, Buchmann E, Bayever DN, Meyer LC. A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections. AAPS PharmSciTech 9 (2), 505-520 (2008).
    • (2008) AAPS PharmSciTech , vol.9 , Issue.2 , pp. 505-520
    • Ndesendo, V.M.1    Pillay, V.2    Choonara, Y.E.3    Buchmann, E.4    Bayever, D.N.5    Meyer, L.C.6
  • 8
    • 77952488307 scopus 로고    scopus 로고
    • Emerging nanotechnology approaches for HIV/AIDS treatment and prevention
    • Mamo T, Moseman EA, Kolishetti N et al. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomedicine (Lond.) 5 (2), 269-285 (2010).
    • (2010) Nanomedicine (Lond.) , vol.5 , Issue.2 , pp. 269-285
    • Mamo, T.1    Moseman, E.A.2    Kolishetti, N.3
  • 9
    • 80053960975 scopus 로고    scopus 로고
    • PH-responsive nanoparticles releasing tenofovir intended for the prevention of HIV transmission
    • Zhang T, Sturgis TF, Youan BB. pH-responsive nanoparticles releasing tenofovir intended for the prevention of HIV transmission. Eur. J. Pharm. Biopharm. 79 (3), 526-536 (2011).
    • (2011) Eur. J. Pharm. Biopharm. , vol.79 , Issue.3 , pp. 526-536
    • Zhang, T.1    Sturgis, T.F.2    Youan, B.B.3
  • 10
    • 79958792602 scopus 로고    scopus 로고
    • Formulation of tenofovir-loaded functionalized solid lipid nanoparticles intended for HIV prevention
    • Alukda D, Sturgis T, Youan BB. Formulation of tenofovir-loaded functionalized solid lipid nanoparticles intended for HIV prevention. J. Pharm. Sci. 100 (8), 3345-3356 (2011).
    • (2011) J. Pharm. Sci. , vol.100 , Issue.8 , pp. 3345-3356
    • Alukda, D.1    Sturgis, T.2    Youan, B.B.3
  • 11
    • 77956078374 scopus 로고    scopus 로고
    • Nanotechnology contributions to the pharmacotherapy of pediatric HIV: A dual scientific and ethical challenge and a still pending agenda
    • Sosnik A. Nanotechnology contributions to the pharmacotherapy of pediatric HIV: a dual scientific and ethical challenge and a still pending agenda. Nanomedicine (Lond.) 5 (6), 833-837 (2010).
    • (2010) Nanomedicine (Lond.) , vol.5 , Issue.6 , pp. 833-837
    • Sosnik, A.1
  • 12
    • 81255195831 scopus 로고    scopus 로고
    • Chitosan/PLGA particles for controlled release of alpha-tocopherol in the GI tract via oral administration
    • Murugeshu A, Astete C, Leonardi C, Morgan T, Sabliov CM. Chitosan/PLGA particles for controlled release of alpha-tocopherol in the GI tract via oral administration. Nanomedicine (Lond.) 6 (9), 1513-1528 (2011).
    • (2011) Nanomedicine (Lond.) , vol.6 , Issue.9 , pp. 1513-1528
    • Murugeshu, A.1    Astete, C.2    Leonardi, C.3    Morgan, T.4    Sabliov, C.M.5
  • 13
    • 0347985635 scopus 로고    scopus 로고
    • Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: Synthesis and in vitro evaluation
    • Roldo M, Hornof M, Caliceti P, Bernkop-Schnurch A. Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation. Eur. J. Pharm. Biopharm. 57 (1), 115-121 (2004).
    • (2004) Eur. J. Pharm. Biopharm. , vol.57 , Issue.1 , pp. 115-121
    • Roldo, M.1    Hornof, M.2    Caliceti, P.3    Bernkop-Schnurch, A.4
  • 14
    • 26644452975 scopus 로고    scopus 로고
    • Thiomers: A new generation of mucoadhesive polymers
    • Bernkop-Schnurch A. Thiomers: a new generation of mucoadhesive polymers. Adv. Drug Deliv. Rev. 57 (11), 1569-1582 (2005).
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , Issue.11 , pp. 1569-1582
    • Bernkop-Schnurch, A.1
  • 15
    • 0042140521 scopus 로고    scopus 로고
    • Thiolated polymers: Evidence for the formation of disulphide bonds with mucus glycoproteins
    • Leitner VM, Walker GF, Bernkop-Schnurch A. Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins. Eur. J. Pharm. Biopharm. 56 (2), 207-214 (2003).
    • (2003) Eur. J. Pharm. Biopharm. , vol.56 , Issue.2 , pp. 207-214
    • Leitner, V.M.1    Walker, G.F.2    Bernkop-Schnurch, A.3
  • 16
    • 80052029739 scopus 로고    scopus 로고
    • Engineering tenofovir loaded chitosan nanoparticles to maximize microbicide mucoadhesion
    • Meng J, Sturgis TF, Youan BB. Engineering tenofovir loaded chitosan nanoparticles to maximize microbicide mucoadhesion. Eur. J. Pharm. Sci. 44 (1-2), 57-67 (2011).
    • (2011) Eur. J. Pharm. Sci. , vol.44 , Issue.1-2 , pp. 57-67
    • Meng, J.1    Sturgis, T.F.2    Youan, B.B.3
  • 17
    • 0038751836 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate
    • Grim SA, Romanelli F. Tenofovir disoproxil fumarate. Ann. Pharmacother. 37 (6), 849-859 (2003).
    • (2003) Ann. Pharmacother. , vol.37 , Issue.6 , pp. 849-859
    • Grim, S.A.1    Romanelli, F.2
  • 18
    • 41849098142 scopus 로고    scopus 로고
    • Stability of chitosan nanoparticles for l-ascorbic acid during heat treatment in aqueous solution
    • Jang KI, Lee HG. Stability of chitosan nanoparticles for l-ascorbic acid during heat treatment in aqueous solution. J. Agric. Food Chem. 56 (6), 1936-1941 (2008).
    • (2008) J. Agric. Food Chem. , vol.56 , Issue.6 , pp. 1936-1941
    • Jang, K.I.1    Lee, H.G.2
  • 20
    • 33744992490 scopus 로고    scopus 로고
    • Visualization of the penetrative and mucoadhesive properties of chitosan and chitosan-coated liposomes through the rat intestine
    • Thongborisute J, Takeuchi H, Yamamoto H, Kawashima Y. Visualization of the penetrative and mucoadhesive properties of chitosan and chitosan-coated liposomes through the rat intestine. J. Liposome Res. 16 (2), 127-141 (2006).
    • (2006) J. Liposome Res. , vol.16 , Issue.2 , pp. 127-141
    • Thongborisute, J.1    Takeuchi, H.2    Yamamoto, H.3    Kawashima, Y.4
  • 21
    • 0344946091 scopus 로고    scopus 로고
    • Uptake of chitosan and associated insulin in Caco-2 cell monolayers: A comparison between chitosan molecules and chitosan nanoparticles
    • Ma Z, Lim LY. Uptake of chitosan and associated insulin in Caco-2 cell monolayers: a comparison between chitosan molecules and chitosan nanoparticles. Pharm. Res. 20 (11), 1812-1819 (2003).
    • (2003) Pharm. Res. , vol.20 , Issue.11 , pp. 1812-1819
    • Ma, Z.1    Lim, L.Y.2
  • 22
    • 42949093768 scopus 로고    scopus 로고
    • Dynamic light scattering for the characterization of polydisperse fractal systems: II.Relation between structure and DLS results
    • Kätzel U, Vorbau M, Stintz M, Gottschalk-Gaudig T, Barthel H. Dynamic light scattering for the characterization of polydisperse fractal systems: II. Relation between structure and DLS results. Part. Syst. Charact. 25, 19-30 (2008).
    • (2008) Part. Syst. Charact. , vol.25 , pp. 19-30
    • Kätzel, U.1    Vorbau, M.2    Stintz, M.3    Gottschalk-Gaudig, T.4    Barthel, H.5
  • 23
    • 52449109917 scopus 로고    scopus 로고
    • Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products
    • Sassi AB, Isaacs CE, Moncla BJ, Gupta P, Hillier SL, Rohan LC. Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products. J. Pharm. Sci. 97 (8), 3123-3139 (2008).
    • (2008) J. Pharm. Sci. , vol.97 , Issue.8 , pp. 3123-3139
    • Sassi, A.B.1    Isaacs, C.E.2    Moncla, B.J.3    Gupta, P.4    Hillier, S.L.5    Rohan, L.C.6
  • 24
    • 0035837392 scopus 로고    scopus 로고
    • Structures and thermal properties of chitosan-modified poly(methyl methacrylate)
    • Don TM, Hsu SH, Chiu WY. Structures and thermal properties of chitosan-modified poly(methyl methacrylate). J. Polym. Sci. 39, 1646-1655 (2001).
    • (2001) J. Polym. Sci. , vol.39 , pp. 1646-1655
    • Don, T.M.1    Hsu, S.H.2    Chiu, W.Y.3
  • 25
    • 79952794432 scopus 로고    scopus 로고
    • Development of hydroxyapatite-ciprofloxacin bone-implants using "quality by design"
    • Nayak AK, Laha B, Sen KK. Development of hydroxyapatite-ciprofloxacin bone-implants using "quality by design". Acta Pharm. 61 (1), 25-36 (2011).
    • (2011) Acta Pharm. , vol.61 , Issue.1 , pp. 25-36
    • Nayak, A.K.1    Laha, B.2    Sen, K.K.3
  • 26
    • 42949112963 scopus 로고    scopus 로고
    • Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides
    • Lackman-Smith C, Osterling C, Luckenbaugh K et al. Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides. Antimicrob. Agents Chemother. 52 (5), 1768-1781 (2008).
    • (2008) Antimicrob. Agents Chemother. , vol.52 , Issue.5 , pp. 1768-1781
    • Lackman-Smith, C.1    Osterling, C.2    Luckenbaugh, K.3
  • 27
    • 0001877280 scopus 로고    scopus 로고
    • Antibacterial susceptibility tests: Dilution and disk diffusion methods
    • Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (Eds) ASM Press, Washington DC, USA
    • Jorgenson JH, Turnidge JD, Washington JA et al. Antibacterial susceptibility tests: dilution and disk diffusion methods. In: Manual of Clinical Microbiology (Seventh Edition). Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (Eds). ASM Press, Washington DC, USA, 1327-1341 (1999).
    • (1999) Manual of Clinical Microbiology (Seventh Edition) , pp. 1327-1341
    • Jorgenson, J.H.1    Turnidge, J.D.2    Washington, J.A.3
  • 28
    • 29244491101 scopus 로고    scopus 로고
    • Self-assembled biodegradable nanoparticles developed by direct dialysis for the delivery of paclitaxel
    • Xie J, Wang CH. Self-assembled biodegradable nanoparticles developed by direct dialysis for the delivery of paclitaxel. Pharm. Res. 22 (12), 2079-2090 (2005).
    • (2005) Pharm. Res. , vol.22 , Issue.12 , pp. 2079-2090
    • Xie, J.1    Wang, C.H.2
  • 29
    • 84855668642 scopus 로고    scopus 로고
    • In vitro response of human chondrocytes to a combination of growth factors and a proteinase inhibitor
    • Pifer MA, Kibuule LK, Maerz T, Studzinski DM, Baker KC, Herkowitz HN. In vitro response of human chondrocytes to a combination of growth factors and a proteinase inhibitor. Orthopedics 35 (1), 35-42 (2012).
    • (2012) Orthopedics , vol.35 , Issue.1 , pp. 35-42
    • Pifer, M.A.1    Kibuule, L.K.2    Maerz, T.3    Studzinski, D.M.4    Baker, K.C.5    Herkowitz, H.N.6
  • 30
    • 39849086966 scopus 로고    scopus 로고
    • Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors
    • Douglas KL, Piccirillo CA, Tabrizian M. Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors. Eur. J. Pharm. Biopharm. 68 (3), 676-687 (2008).
    • (2008) Eur. J. Pharm. Biopharm. , vol.68 , Issue.3 , pp. 676-687
    • Douglas, K.L.1    Piccirillo, C.A.2    Tabrizian, M.3
  • 31
    • 0024352077 scopus 로고
    • A novel in situ method to test polymers and coated microparticles for bioadhesion
    • Ranga Rao KV, Buri P. A novel in situ method to test polymers and coated microparticles for bioadhesion. Endocr. Rev. 52 15 (13), 265-270 (1989).
    • (1989) Endocr. Rev. , vol.5215 , Issue.13 , pp. 265-270
    • Ranga Rao, K.V.1    Buri, P.2
  • 32
    • 33750891059 scopus 로고    scopus 로고
    • Preparation of thiomer microparticles and in vitro evaluation of parameters influencing their mucoadhesive properties
    • Albrecht K, Zirm EJ, Palmberger TF, Schlocker W, Bernkop-Schnurch A. Preparation of thiomer microparticles and in vitro evaluation of parameters influencing their mucoadhesive properties. Drug. Dev. Ind. Pharm. 32 (10), 1149-1157 (2006).
    • (2006) Drug. Dev. Ind. Pharm. , vol.32 , Issue.10 , pp. 1149-1157
    • Albrecht, K.1    Zirm, E.J.2    Palmberger, T.F.3    Schlocker, W.4    Bernkop-Schnurch, A.5
  • 33
    • 26644434123 scopus 로고    scopus 로고
    • Comparison of the mucoadhesive properties of various polymers
    • Grabovac V, Guggi D, Bernkop-Schnurch A. Comparison of the mucoadhesive properties of various polymers. Adv. Drug Deliv. Rev. 57 (11), 1713-1723 (2005).
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , Issue.11 , pp. 1713-1723
    • Grabovac, V.1    Guggi, D.2    Bernkop-Schnurch, A.3
  • 34
    • 77953127556 scopus 로고    scopus 로고
    • Bioadhesive chitosan nanoparticles: Preparation and characterization
    • Dudhania A, Kosaraju S. Bioadhesive chitosan nanoparticles: preparation and characterization. Carbohyd. Polym. 81, 243-251 (2010).
    • (2010) Carbohyd. Polym. , vol.81 , pp. 243-251
    • Dudhania, A.1    Kosaraju, S.2
  • 35
    • 33745339074 scopus 로고    scopus 로고
    • Reverse hexagonal phase nanodispersion of monoolein and oleic acid for topical delivery of peptides: In vitro and in vivo skin penetration of cyclosporin A
    • Lopes LB, Ferreira DA, De Paula D et al. Reverse hexagonal phase nanodispersion of monoolein and oleic acid for topical delivery of peptides: in vitro and in vivo skin penetration of cyclosporin A. Pharm. Res. 23 (6), 1332-1342 (2006).
    • (2006) Pharm. Res. , vol.23 , Issue.6 , pp. 1332-1342
    • Lopes, L.B.1    Ferreira, D.A.2    De Paula, D.3
  • 36
    • 33748353667 scopus 로고
    • Response surface methods and design
    • John Wiley and Sons Inc., NY, USA
    • Montgomery D. Response surface methods and design. In: Design and Analysis of Experiments. John Wiley and Sons Inc., NY, USA, 405-458 (1995).
    • (1995) Design and Analysis of Experiments , pp. 405-458
    • Montgomery, D.1
  • 37
    • 34347373866 scopus 로고    scopus 로고
    • Statistical designs and response surface techniques for the optimization of chromatographic systems
    • Ferreira SL, Bruns RE, Da Silva EG et al. Statistical designs and response surface techniques for the optimization of chromatographic systems. J. Chromatogr. A 1158 (1-2), 2-14 (2007).
    • (2007) J. Chromatogr. A , vol.1158 , Issue.1-2 , pp. 2-14
    • Ferreira, S.L.1    Bruns, R.E.2    Da Silva, E.G.3
  • 40
    • 70449522055 scopus 로고    scopus 로고
    • Formulation of dacarbazine-loaded cubosomes-part II: Influence of process parameters
    • Bei D, Marszalek J, Youan BB. Formulation of dacarbazine-loaded cubosomes-part II: influence of process parameters. AAPS Pharm Sci Tech 10 (3), 1040-1047 (2009).
    • (2009) AAPS Pharm Sci Tech , vol.10 , Issue.3 , pp. 1040-1047
    • Bei, D.1    Marszalek, J.2    Youan, B.B.3
  • 41
    • 79551479125 scopus 로고    scopus 로고
    • Chitosan nanoparticles of 5-fluorouracil for ophthalmic delivery: Characterization, in-vitro and in-vivo study
    • Nagarwal RC, Singh PN, Kant S, Maiti P, Pandit JK. Chitosan nanoparticles of 5-fluorouracil for ophthalmic delivery: characterization, in-vitro and in-vivo study. Chem. Pharm. Bull. (Tokyo) 59 (2), 272-278 (2011).
    • (2011) Chem. Pharm. Bull. (Tokyo) , vol.59 , Issue.2 , pp. 272-278
    • Nagarwal, R.C.1    Singh, P.N.2    Kant, S.3    Maiti, P.4    Pandit, J.K.5
  • 42
    • 39749120051 scopus 로고    scopus 로고
    • PH-dependent interactions of indinavir and lipids in nanoparticles and their ability to entrap a solute
    • Choi SU, Bui T, Ho RJ. pH-dependent interactions of indinavir and lipids in nanoparticles and their ability to entrap a solute. J. Pharm. Sci. 97 (2), 931-943 (2008).
    • (2008) J. Pharm. Sci. , vol.97 , Issue.2 , pp. 931-943
    • Choi, S.U.1    Bui, T.2    Ho, R.J.3
  • 43
    • 0032886954 scopus 로고    scopus 로고
    • Evaluation of the potential of ion pair formation to improve the oral absorption of two potent antiviral compounds AMD3100 and PMPA
    • Van Gelder J, Witvrouw M, Pannecouque C et al. Evaluation of the potential of ion pair formation to improve the oral absorption of two potent antiviral compounds, AMD3100 and PMPA. Int. J. Pharm. 186 (2), 127-136 (1999).
    • (1999) Int. J. Pharm. , vol.186 , Issue.2 , pp. 127-136
    • Van Gelder, J.1    Witvrouw, M.2    Pannecouque, C.3
  • 44
    • 33947482089 scopus 로고
    • Dithiothreitol, a new protective reagent for Sh groups
    • Cleland WW. Dithiothreitol, a new protective reagent for Sh groups. Biochemistry 3, 480-482 (1964).
    • (1964) Biochemistry , vol.3 , pp. 480-482
    • Cleland, W.W.1
  • 45
    • 51649130771 scopus 로고    scopus 로고
    • Optimization of fabrication parameters to produce chitosan-tripolyphosphate nanoparticles for delivery of tea catechins
    • Hu B, Pan C, Sun Y, Hou Z, Ye H, Zeng X. Optimization of fabrication parameters to produce chitosan-tripolyphosphate nanoparticles for delivery of tea catechins. J. Agric. Food. Chem. 56 (16), 7451-7458 (2008).
    • (2008) J. Agric. Food. Chem. , vol.56 , Issue.16 , pp. 7451-7458
    • Hu, B.1    Pan, C.2    Sun, Y.3    Hou, Z.4    Ye, H.5    Zeng, X.6
  • 46
    • 67650065139 scopus 로고    scopus 로고
    • Chitosan/TPP and chitosan/TPP-hyaluronic acid nanoparticles: Systematic optimisation of the preparative process and preliminary biological evaluation
    • Nasti A, Zaki NM, De Leonardis P et al. Chitosan/TPP and chitosan/TPP-hyaluronic acid nanoparticles: systematic optimisation of the preparative process and preliminary biological evaluation. Pharm. Res. 26 (8), 1918-1930 (2009).
    • (2009) Pharm. Res. , vol.26 , Issue.8 , pp. 1918-1930
    • Nasti, A.1    Zaki, N.M.2    De Leonardis, P.3
  • 47
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim SS, Frohlich JA et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 329 (5996), 1168-1174 (2010).
    • (2010) Science , vol.329 , Issue.5996 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2    Frohlich, J.A.3
  • 48
    • 0035073301 scopus 로고    scopus 로고
    • Modeling and comparison of dissolution profiles
    • Costa P, Sousa Lobo JM. Modeling and comparison of dissolution profiles. Eur. J. Pharm. Sci. 13 (2), 123-133 (2001).
    • (2001) Eur. J. Pharm. Sci. , vol.13 , Issue.2 , pp. 123-133
    • Costa, P.1    Sousa Lobo, J.M.2
  • 49
    • 33749666655 scopus 로고    scopus 로고
    • Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: A technical note
    • Merchant HA, Shoaib HM, Tazeen J, Yousuf R. Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: a technical note. AAPS Pharm Sci Tech 7 (3), 78 (2006).
    • (2006) AAPS Pharm Sci Tech , vol.7 , Issue.3 , pp. 78
    • Merchant, H.A.1    Shoaib, H.M.2    Tazeen, J.3    Yousuf, R.4
  • 50
    • 77950361652 scopus 로고    scopus 로고
    • Strategies to prolong the intravaginal residence time of drug delivery systems
    • Baloglu E, Senyigit ZA, Karavana SY, Bernkop-Schnurch A. Strategies to prolong the intravaginal residence time of drug delivery systems. J. Pharm. Sci. 12 (3), 312-336 (2009).
    • (2009) J. Pharm. Sci. , vol.12 , Issue.3 , pp. 312-336
    • Baloglu, E.1    Senyigit, Z.A.2    Karavana, S.Y.3    Bernkop-Schnurch, A.4
  • 51
    • 18244398917 scopus 로고    scopus 로고
    • Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue
    • Lee WA, He GX, Eisenberg E et al. Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue. Antimicrob. Agents Chemother. 49 (5), 1898-1906 (2005).
    • (2005) Antimicrob. Agents Chemother. , vol.49 , Issue.5 , pp. 1898-1906
    • Lee, W.A.1    He, G.X.2    Eisenberg, E.3
  • 52
    • 67650349138 scopus 로고    scopus 로고
    • Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441
    • Uboldi C, Bonacchi D, Lorenzi G et al. Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441. Part Fibre Toxicol. 6, 18 (2009).
    • (2009) Part Fibre Toxicol. , vol.6 , pp. 18
    • Uboldi, C.1    Bonacchi, D.2    Lorenzi, G.3
  • 53
    • 36048937333 scopus 로고    scopus 로고
    • Effects of nanoparticles on the adhesion and cell viability on astrocytes
    • Au C, Mutkus L, Dobson A, Riffle J, Lalli J, Aschner M. Effects of nanoparticles on the adhesion and cell viability on astrocytes. Biol. Trace Elem. Res. 120 (1-3), 248-256 (2007).
    • (2007) Biol. Trace Elem. Res. , vol.120 , Issue.1-3 , pp. 248-256
    • Au, C.1    Mutkus, L.2    Dobson, A.3    Riffle, J.4    Lalli, J.5    Aschner, M.6
  • 54
    • 1242336856 scopus 로고    scopus 로고
    • Identification and H2O2 production of vaginal lactobacilli from pregnant women at high risk of preterm birth and relation with outcome
    • Wilks M, Wiggins R, Whiley A et al. Identification and H2O2 production of vaginal lactobacilli from pregnant women at high risk of preterm birth and relation with outcome. J. Clin. Microbiol. 42 (2), 713-717 (2004).
    • (2004) J. Clin. Microbiol. , vol.42 , Issue.2 , pp. 713-717
    • Wilks, M.1    Wiggins, R.2    Whiley, A.3
  • 55
    • 27744555553 scopus 로고    scopus 로고
    • Comparison between Gram stain and culture for the characterization of vaginal microflora: Definition of a distinct grade that resembles grade i microflora and revised categorization of grade i microflora
    • Verhelst R, Verstraelen H, Claeys G et al. Comparison between Gram stain and culture for the characterization of vaginal microflora: definition of a distinct grade that resembles grade I microflora and revised categorization of grade I microflora. BMC Microbiol. 5, 61 (2005).
    • (2005) BMC Microbiol. , vol.5 , pp. 61
    • Verhelst, R.1    Verstraelen, H.2    Claeys, G.3
  • 56
    • 0019829488 scopus 로고
    • Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change
    • Casella JF, Flanagan MD, Lin S. Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change. Nature 293 (5830), 302-305 (1981).
    • (1981) Nature , vol.293 , Issue.5830 , pp. 302-305
    • Casella, J.F.1    Flanagan, M.D.2    Lin, S.3
  • 57
    • 0027716492 scopus 로고
    • Cytoskeletal control of the apical surface transformation of rat uterine epithelium
    • Luxford KA, Murphy CR. Cytoskeletal control of the apical surface transformation of rat uterine epithelium. Biol. Cell 79 (2), 111-116 (1993).
    • (1993) Biol. Cell , vol.79 , Issue.2 , pp. 111-116
    • Luxford, K.A.1    Murphy, C.R.2
  • 58
    • 79959811662 scopus 로고    scopus 로고
    • Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism
    • Meng H, Yang S, Li Z et al. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. ACS Nano 5 (6), 4434-4447 (2011).
    • (2011) ACS Nano , vol.5 , Issue.6 , pp. 4434-4447
    • Meng, H.1    Yang, S.2    Li, Z.3
  • 59
    • 65449120034 scopus 로고    scopus 로고
    • Virus entry by macropinocytosis
    • Mercer J, Helenius A. Virus entry by macropinocytosis. Nat. Cell Biol. 11 (5), 510-520 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , Issue.5 , pp. 510-520
    • Mercer, J.1    Helenius, A.2
  • 60
    • 46549084447 scopus 로고    scopus 로고
    • The effect of surface functionality on cellular trafficking of dendrimers
    • Perumal OP, Inapagolla R, Kannan S, Kannan RM. The effect of surface functionality on cellular trafficking of dendrimers. Biomaterials 29 (24-25), 3469-3476 (2008).
    • (2008) Biomaterials , vol.29 , Issue.24-25 , pp. 3469-3476
    • Perumal, O.P.1    Inapagolla, R.2    Kannan, S.3    Kannan, R.M.4
  • 61
    • 0033968050 scopus 로고    scopus 로고
    • JC virus enters human glial cells by clathrin-dependent receptor-mediated endocytosis
    • Pho MT, Ashok A, Atwood WJ. JC virus enters human glial cells by clathrin-dependent receptor-mediated endocytosis. J. Virol. 74 (5), 2288-2292 (2000).
    • (2000) J. Virol. , vol.74 , Issue.5 , pp. 2288-2292
    • Pho, M.T.1    Ashok, A.2    Atwood, W.J.3
  • 62
    • 34447524004 scopus 로고    scopus 로고
    • Clathrin-coated pits: Vive la difference?
    • Benmerah A, Lamaze C. Clathrin-coated pits: vive la difference? Traffic 8 (8), 970-982 (2007).
    • (2007) Traffic , vol.8 , Issue.8 , pp. 970-982
    • Benmerah, A.1    Lamaze, C.2
  • 64
    • 0038677077 scopus 로고    scopus 로고
    • Caveolae-associated proteins in cardiomyocytes: Caveolin-2 expression and interactions with caveolin-3
    • Rybin VO, Grabham PW, Elouardighi H, Steinberg SF. Caveolae-associated proteins in cardiomyocytes: caveolin-2 expression and interactions with caveolin-3. Am. J. Physiol. Heart Circ. Physiol. 285 (1), H325-H332 (2003).
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285 , Issue.1 , pp. H325-H332
    • Rybin, V.O.1    Grabham, P.W.2    Elouardighi, H.3    Steinberg, S.F.4
  • 65
    • 79551648929 scopus 로고    scopus 로고
    • Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro
    • Georgieva JV, Kalicharan D, Couraud PO et al. Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro. Mol. Ther. 19 (2), 318-325 (2011).
    • (2011) Mol. Ther. , vol.19 , Issue.2 , pp. 318-325
    • Georgieva, J.V.1    Kalicharan, D.2    Couraud, P.O.3
  • 66
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis
    • Rejman J, Oberle V, Zuhorn IS, Hoekstra D. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem. J. 377 (Pt 1), 159-169 (2004).
    • (2004) Biochem. J. , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3    Hoekstra, D.4
  • 67
    • 3042696831 scopus 로고    scopus 로고
    • Caveolae-an alternative endocytotic pathway for targeted drug delivery
    • Bathori G, Cervenak L, Karadi I. Caveolae-an alternative endocytotic pathway for targeted drug delivery. Crit. Rev. Ther. Drug Carrier Syst. 21 (2), 67-95 (2004).
    • (2004) Crit. Rev. Ther. Drug Carrier Syst. , vol.21 , Issue.2 , pp. 67-95
    • Bathori, G.1    Cervenak, L.2    Karadi, I.3
  • 68
    • 78349309344 scopus 로고    scopus 로고
    • Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(gamma-glutamic acid) complexes as a gene delivery vector
    • Peng SF, Tseng MT, Ho YC, Wei MC, Liao ZX, Sung HW. Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(gamma-glutamic acid) complexes as a gene delivery vector. Biomaterials 32 (1), 239-248 (2011).
    • (2011) Biomaterials , vol.32 , Issue.1 , pp. 239-248
    • Peng, S.F.1    Tseng, M.T.2    Ho, Y.C.3    Wei, M.C.4    Liao, Z.X.5    Sung, H.W.6
  • 69
    • 24144439116 scopus 로고    scopus 로고
    • Role of endocytosis in cellular uptake of sex steroids
    • Hammes A, Andreassen TK, Spoelgen R et al. Role of endocytosis in cellular uptake of sex steroids. Cell 122 (5), 751-762 (2005).
    • (2005) Cell , vol.122 , Issue.5 , pp. 751-762
    • Hammes, A.1    Andreassen, T.K.2    Spoelgen, R.3
  • 71
    • 0033020555 scopus 로고    scopus 로고
    • Polymers with thiol groups: A new generation of mucoadhesive polymers?
    • Bernkop-Schnurch A, Schwarz V, Steininger S. Polymers with thiol groups: a new generation of mucoadhesive polymers? Pharm. Res. 16 (6), 876-881 (1999).
    • (1999) Pharm. Res. , vol.16 , Issue.6 , pp. 876-881
    • Bernkop-Schnurch, A.1    Schwarz, V.2    Steininger, S.3
  • 72
    • 38349132357 scopus 로고    scopus 로고
    • Porcine vagina ex vivo as a model for studying permeability and pathogenesis in mucosa
    • Squier CA, Mantz MJ, Schlievert PM, Davis CC. Porcine vagina ex vivo as a model for studying permeability and pathogenesis in mucosa. J. Pharm. Sci. 97 (1), 9-21 (2008).
    • (2008) J. Pharm. Sci. , vol.97 , Issue.1 , pp. 9-21
    • Squier, C.A.1    Mantz, M.J.2    Schlievert, P.M.3    Davis, C.C.4
  • 73
    • 0344443713 scopus 로고    scopus 로고
    • The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa
    • Nicolazzo JA, Reed BL, Finnin BC. The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa. J. Pharm. Sci. 92 (12), 2399-2410 (2003).
    • (2003) J. Pharm. Sci. , vol.92 , Issue.12 , pp. 2399-2410
    • Nicolazzo, J.A.1    Reed, B.L.2    Finnin, B.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.