Neuroprotective effect of epigallocatechin-3-gallate against β-amyloid-induced oxidative and nitrosative cell death via augmentation of antioxidant defense capacity

Archives of Pharmacal Research

Volumn 32, Issue 6, 2009, Pages 869-881

  Kim, Chang Yul ^a   Lee, Chan ^a   Park, Gyu Hwan ^b   Jang, Jung Hee ^a  

^a Daegu Haany University   (South Korea)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Amyloid; Glutamylcysteine ligase; Alzheimer's disease; Apoptosis; Epigallocatechin 3 gallate; Glutathione; Oxidative and nitrosative stress

Indexed keywords

ACTIN; AMYLOID BETA PROTEIN; DNA FRAGMENT; EPIGALLOCATECHIN GALLATE; GAMMA GLUTAMYLCYSTEINE; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NEUROPROTECTIVE AGENT; NITRIC OXIDE; PEROXYNITRITE; PROTEIN BAX; PROTEIN BCL 2;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; GENE EXPRESSION; MALE; MICROGLIA; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL NECROSIS; NEUROPROTECTION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT; SENILE PLAQUE; SIGNAL TRANSDUCTION; TEA;

AMYLOID BETA-PROTEIN; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CATECHIN; CELL DEATH; CELL LINE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HIPPOCAMPUS; MALE; MICROGLIA; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

EID: 68149160164     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-1609-z     Document Type: Article

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