Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells

Molecular and Cellular Endocrinology

Volumn 419, Issue , 2016, Pages 60-71

  Pratt, Evan P S ^a,b   Salyer, Amy E ^a   Guerra, Marcy L ^a   Hockerman, Gregory H ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Cav1.2; Ca2+ induced Ca2+ release; CAMP; Exchange protein directly activated by cAMP; Extracellular signal regulated kinase 1 2; L type Ca2+ channel; Pancreatic beta cell

Indexed keywords

ANTIPORTER; CALCIUM CHANNEL CAV1.2; CALCIUM CHANNEL L TYPE; CYCLIC AMP; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG; 6-FLUORO-5,7-DIBROMO-2-METHYL-1-FORMYL-1,2,3,4-TETRAHYDROQUINOLINE; BENZENE DERIVATIVE; CALCIUM; EPAC-1 PROTEIN, RAT; ESI-05; GLUCOSE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; NICARDIPINE; QUINOLINE DERIVATIVE; RYANODINE; SULFONE;

ARTICLE; CALCIUM INDUCED CALCIUM RELEASE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INS 1 CELL LINE; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BENZENE DERIVATIVES; CALCIUM; CALCIUM CHANNELS, L-TYPE; CYCLIC AMP; GLUCOSE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MAP KINASE SIGNALING SYSTEM; NICARDIPINE; PHOSPHORYLATION; QUINOLINES; RATS; RYANODINE; SULFONES;

EID: 84949591074     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.09.034     Document Type: Article

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