Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene

Neuropathology and Applied Neurobiology

Volumn 41, Issue 5, 2015, Pages 601-612

  Baborie, Atik ^a   Griffiths, Timothy D ^b   Jaros, Evelyn ^b,c   Perry, Robert ^b,c   McKeith, Ian G ^b   Burn, David J ^b   Masuda Suzukake, Masami ^e   Hasegawa, Masato ^e   Rollinson, Sara ^d   Pickering Brown, Stuart ^d   Robinson, Andrew C ^d   Davidson, Yvonne S ^d   Mann, David M A ^d  

^a WALTON CENTRE FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c ROYAL VICTORIA INFIRMARY   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

C9ORF72; Dipeptide repeat proteins; Frontotemporal lobar degeneration; Hexanucleotide repeat expansion

Indexed keywords

DIPEPTIDE REPEAT PROTEIN; PROTEIN; PROTEIN P62; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; C9ORF72 PROTEIN, HUMAN; DIPEPTIDE; DNA BINDING PROTEIN; REPETITIVE DNA; TDP-43 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BRAIN REGION; BRONCHOPNEUMONIA; C9ORF72 GENE; CEREBELLUM; CLINICAL ARTICLE; CLINICAL FEATURE; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE STRUCTURE; GENETIC ANALYSIS; HEART INFARCTION; HEXANUCLEOTIDE REPEAT; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MEDICAL HISTORY; MIDDLE AGED; MOLECULAR PATHOLOGY; NERVE CELL; NUCLEOTIDE REPEAT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING; BRAIN; CASE REPORT; CELL INCLUSION; GENETICS; METABOLISM; PATHOLOGY;

AGED; BRAIN; DIPEPTIDES; DNA REPEAT EXPANSION; DNA-BINDING PROTEINS; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; INCLUSION BODIES; MALE; MIDDLE AGED; NEURONS; PROTEINS;

EID: 84949104989     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/nan.12178     Document Type: Article

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