Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

Diabetologia

Volumn 59, Issue 1, 2016, Pages 161-169

  Tugay, Ksenia ^a   Guay, Claudiane ^a   Marques, Ana C ^a   Allagnat, Florent ^a   Locke, Jonathan M ^b   Harries, Lorna W ^b   Rutter, Guy A ^c   Regazzi, Romano ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Ageing; Apoptosis; Beta cell; Diabetes; Insulin secretion; MicroRNA; Pancreatic islet; Proliferation

Indexed keywords

INSULIN; MESSENGER RNA; MICRORNA; MICRORNA 124A; MICRORNA 130B; MICRORNA 181A; MICRORNA 34A; MICRORNA 383; PLATELET DERIVED GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG; MIRN124 MICRORNA, RAT; MIRN130 MICRORNA, RAT; MIRN181 MICRORNA, RAT; MIRN34 MICRORNA, RAT; MIRN383 MICRORNA, RAT; TRANSCRIPTOME;

AGE; AGING; ANIMAL CELL; ARTICLE; CELL EXPANSION; CELL FUNCTION; CELL PROLIFERATION; COMPUTER ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA MODIFICATION; DOWN REGULATION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN RESISTANCE; LONG TERM EXPOSURE; MICROARRAY ANALYSIS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; TRANSCRIPTOMICS; UPREGULATION; ANIMAL; APOPTOSIS; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; MALE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

AGING; ANIMALS; APOPTOSIS; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICRORNAS; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSCRIPTOME; TRANSFECTION;

EID: 84949321371     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3783-5     Document Type: Article

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