Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells

BMC Immunology

Volumn 15, Issue 1, 2014, Pages

  Lin, Lin ^a,b,c   Couturier, Jacob ^a   Yu, Xiaoying ^d   Medina, Miguel A ^a   Kozinetz, Claudia A ^d   Lewis, Dorothy E ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b Shandong Center for Disease Control and Prevention   (China)

^c SHANDONG UNIVERSITY   (China)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

ELISA; ELISpot; Flow cytometry; Granzyme B; Memory T cells; Perforin

Indexed keywords

GRANZYME B; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PERFORIN; BIOLOGICAL MARKER; CYTOKINE; GRANZYME;

ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR SECRETION; COMPARATIVE STUDY; CULTURE MEDIUM; DEGRANULATION; DONOR; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; ENZYME RELEASE; ENZYME SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LYMPHOCYTE COUNT; MEMORY T LYMPHOCYTE; NATURAL KILLER CELL; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; PROTEIN SECRETION; PURIFICATION; T LYMPHOCYTE ACTIVATION; BLOOD DONOR; ENZYME ASSAY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; REGULATORY T LYMPHOCYTE; SECRETION (PROCESS); TH1 CELL;

BIOMARKERS; BLOOD DONORS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; ENZYME ASSAYS; GRANZYMES; HUMANS; IMMUNOLOGIC MEMORY; KILLER CELLS, NATURAL; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; PERFORIN; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 84949118360     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/s12865-014-0036-1     Document Type: Article

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