Flow cytometric measurements of TB-specific T cells comparing with quantiFERON-TB gold

Cytometry Part B - Clinical Cytometry

Volumn 78, Issue 2, 2010, Pages 71-80

  Won, Dong Il ^a   Park, Jung Ran ^a  

^a Kyungpook National University School of Medicine   (South Korea)

Author keywords

Flow cytometry; Interferon release assay; Tuberculosis

Indexed keywords

BACTERIAL ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIAGNOSTIC ACCURACY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; INTERMETHOD COMPARISON; INTRACELLULAR CYTOKINE FLOW CYTOMETRY; LIGHT SCATTERING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; T LYMPHOCYTE SUBPOPULATION; TUBERCULOSIS;

ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; INTERFERON-GAMMA; SENSITIVITY AND SPECIFICITY; TUBERCULOSIS;

EID: 77749292788     PISSN: 15524949     EISSN: 15524957     Source Type: Journal    
DOI: 10.1002/cyto.b.20503     Document Type: Article

References (28)

1. Rook GA, Dheda K, Zumla A. Immune responses to tuberculosis in developing countries: Implications for new vaccines. Nat Rev Immunol 2005;5:661-667.
2. Hughes AJ, Hutchinson P, Gooding T, Freezer NJ, Holdsworth SR, Johnson PD. Diagnosis of Mycobacterium tuberculosis infection using ESAT-6 and intracellular cytokine cytometry. Clin Exp Immunol 2005;142:132-139.
3. Keeler E, Perkins MD, Small P, Hanson C, Reed S, Cunningham J, Aledort JE, Hillborne L, Rafael ME, Girosi F, Dye C. Reducing the global burden of tuberculosis: The contribution of improved diagnostics. Nature 2006;444(Suppl 1):49-57.
4. Palme IB, Gudetta B, Bruchfeld J, Muhe L, Giesecke J. Impact of human immunodeficiency virus 1 infection on clinical presentation, treatment outcome and survival in a cohort of Ethiopian children with tuberculosis. Pediatr Infect Dis J 2002;21:1053-1061.
5. Mazurek GH, Jereb J, Lobue P, Iademarco MF, Metchock B, Vernon A. Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep 2005;54:49-55.
6. Cardoso FL, Antas PR, Milagres AS, Geluk A, Franken KL, Oliveira EB, Teixeira HC, Nogueira SA, Sarno EN, Klatser P, Ottenhoff TH, Sampaio EP. T-cell responses to the Mycobacterium tuberculosis-specific antigen ESAT-6 in Brazilian tuberculosis patients. Infect Immun 2002;70:6707-6714.
7. Fuhrmann S, Streitz M, Kern F. How flow cytometry is changing the study of TB immunology and clinical diagnosis. Cytometry A 2008;73A:1100-1106.
8. Janossy G, Barry SM, Breen RA, Hardy GA, Lipman M, Kern F. The role of flow cytometry in the interferon-gamma-based diagnosis of active tuberculosis and its coinfection with HIV-1-A technically oriented review. Cytometry B Clin Cytom 2008;74B(Suppl 1):S141-S151.
9. Barry SM, Lipman MC, Bannister B, Johnson MA, Janossy G. Purified protein derivative-activated type 1 cytokine-producing CD4+ T lymphocytes in the lung: A characteristic feature of active pulmonary and nonpulmonary tuberculosis. J Infect Dis 2003;187:243-250.
10. Tesfa L, Koch FW, Pankow W, Volk HD, Kern F. Confirmation of Mycobacterium tuberculosis infection by flow cytometry after ex vivo incubation of peripheral blood T cells with an ESAT-6-derived peptide pool. Cytometry B Clin Cytom 2004;60B:47-53.
11. Streitz M, Tesfa L, Yildirim V, Yahyazadeh A, Ulrichs T, Lenkei R, Quassem A, Liebetrau G, Nomura L, Maecker H, Volk HD, Kern F. Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis. PLoS One 2007;2:e735.
12. Cosmi L, Maggi L, Santarlasci V, Liotta F, Frosali F, Angeli R, Mazzetti M, Vultaggio A, Matucci A, Maggi E, Romagnani S, Annunziato F. Detection by flow cytometry of ESAT-6- and PPD-specific circulating CD4+ T lymphocytes as a diagnostic tool for tuberculosis. Int Arch Allergy Immunol 2007;143:1-9.
13. Dinser R, Fousse M, Sester U, Albrecht K, Singh M, Köhler H, Müller-Ladner U. Sester evaluation of latent tuberculosis infection in patients with inflammatory arthropathies before treatment with TNF-alpha blocking drugs using a novel flow-cytometric interferon-gamma release assay. Rheumatology (Oxford) 2008;47:212-218.
14. Leung WL, Law KL, Leung VS, Yip CW, Leung CC, Tam CM, Kam KM. Comparison of intracellular cytokine flow cytometry and an enzyme immunoassay for evaluation of cellular immune response to active tuberculosis. Clin Vaccine Immunol 2009;16:344-351.
15. Breen RA, Barry SM, Smith CJ, Shorten RJ, Dilworth JP, Cropley I, McHugh TD, Gillespie SH, Janossy G, Lipman MC. Clinical application of a rapid lung-orientated immunoassay in individuals with possible tuberculosis. Thorax 2008;63:67-71.
16. Breen RA, Hardy GA, Perrin FM, Lear S, Kinloch S, Smith CJ, Cropley I, Janossy G, Lipman MC. Rapid diagnosis of smear-negative tuberculosis using immunology and microbiology with induced sputum in HIV-infected and uninfected individuals. PLoS One 2007;2:e1335.
17. Arend SM, Ottenhoff TH, Andersen P, van Dissel JT. Uncommon presentations of tuberculosis: The potential value of a novel diagnostic assay based on the Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10. Int J Tuberc Lung Dis 2001;5:680-686.
18. Maecker HT, Moon J, Bhatia S, Ghanekar SA, Maino VC, Payne JK, Kuus-Reichel K, Chang JC, Summers A, Clay TM, Morse MA, Lyerly HK, DeLaRosa C, Ankerst DP, Disis ML. Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT. BMC Immunol 2005;6:17.
19. Vekemans J, Lienhardt C, Sillah JS, Wheeler JG, Lahai GP, Doherty MT, Corrah T, Andersen P, McAdam KP, Marchant A. Tuberculosis contacts but not patients have higher gamma interferon responses to ESAT-6 than do community controls in The Gambia. Infect Immun 2001;69:6554-6557.
20. Antas PR, Cardoso FL, Pereira KC, Franken KL, Cunha KS, Klatser P, Sarno EN, Ottenhoff TH, Sampaio EP. T cell immune responses to mycobacterial antigens in Brazilian tuberculosis patients and controls. Trans R Soc Trop Med Hyg 2005;99:699-707.
21. Roederer M. How many events is enough? Are you positive? Cytometry A 2008;73A:384-385.
22. Nomura L, Maino VC, Maecker HT. Standardization and optimization of multiparameter intracellular cytokine staining. Cytometry A 2008;73A:984-991.
23. Islam N, Kanost AR, Teixeira L, Johnson J, Hejal R, Aung H, Wilkinson RJ, Hirsch CS, Toossi Z. Role of cellular activation and tumor necrosis factor in the early expression of Mycobacterium tuberculosis 85B mRNA in human alveolar macrophages. J Infect Dis 2004;190:341-351.
24. Surcel HM, Troye-Blomberg M, Paulie S, Andersson G, Moreno C, Pasvol G, Ivanyi J. Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens. Immunology 1994;81:171-176.
25. Waters WR, Palmer MV, Pesch BA, Olsen SC, Wannemuehler MJ, Whipple DL. Lymphocyte subset proliferative responses of Mycobacterium bovis-infected cattle to purified protein derivative. Vet Immunol Immunopathol 2000;77:257-273.
26. Kern F, Faulhaber N, Frommel C, Khatamzas E, Prosch S, Schonemann C, Kretzschmar I, Volkmer-Engert R, Volk HD, Reinke P. Analysis of CD8 T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides. Eur J Immunol 2000;30:1676-1682.
27. Murray RA, Mansoor N, Harbacheuski R, Soler J, Davids V, Soares A, Hawkridge A, Hussey GD, Maecker H, Kaplan G, Hanekom WA. Bacillus Calmette Guerin vaccination of human newborns induces a specific, functional CD8+ T cell response. J Immunol 2006;177: 5647-5651.
28. Kaufmann SH. How can immunology contribute to the control of tuberculosis? Nat Rev Immunol 2001;1:20-30.